Basal Cell Carcinoma News and Research

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Basal cell cancer begins in the lowest layer of the epidermis, the basal cell layer. About 8 out of 10 skin cancers are basal cell carcinomas. They usually begin on areas exposed to the sun, such as the head and neck. Basal cell carcinoma was once found mostly in middle-aged or older people. But now it is also being seen in younger people. This may be because people are spending more time in the sun without protecting their skin.

Basal cell carcinoma tends to grow slowly. It is very rare for a basal cell cancer to spread to distant parts of the body (metastasize). But if it is not treated, it can grow into nearby areas and spread into the bone or other tissues beneath the skin.

After treatment, basal cell carcinoma can come back (recur) in the same place on the skin. New basal cell cancers can also start in other places on the skin. As many as half of the people who have one basal cell cancer will get a new skin cancer within 5 years.

Childhood obesity not linked to adult skin cancer risk, study says

Study leverages a Mendelian randomization approach to explore if childhood obesity genetically predisposes individuals to adult skin cancer, finding no significant correlation.

7 Apr 2024

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

7 Mar 2024

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Study links specific inflammatory markers to increased cancer risk

The causal relevance of circulating inflammatory markers in cancer risk.

5 Feb 2024

Study reveals mechanisms restricting oncogene-driven skin cancer formation

To form a cancer, cells need to accumulate oncogenic mutations that confer tumor-initiating properties.

15 Nov 2023

New AI software achieves 100% detection rate for melanoma

Skin cancer detection using artificial intelligence (AI) software has rapidly improved, new research has shown, with the latest software reaching a 100% detection rate for melanoma.

11 Oct 2023

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Non-melanoma skin cancer (NMSC) is causing a greater number of global deaths than melanoma, the more serious form of skin cancer, a new study presented today at the European Academy of Dermatology and Venerology (EADV) Congress 2023 has found.

10 Oct 2023

Rockefeller researchers reveal the mechanisms behind malignant turn of events in cancer

Early on, every stem cell faces a fateful choice. During skin development, for instance, the embryonic epidermis begins as a single layer of epidermal progenitor cells.

31 Jul 2023

Reinforcement learning improves performance of AI-based skin cancer diagnosis

Artificial intelligence (AI) is already being used to diagnose skin cancer, but it cannot (yet) keep pace with the complex decision-making of doctors in practice.

28 Jul 2023

For uninsured people with cancer, securing care can be like spinning a roulette wheel

Eighteen months after April Adcox learned she had skin cancer, she finally returned to Charleston's Medical University of South Carolina last May to seek treatment.

10 Apr 2023

People with atopy have lower prevalence of cancers in extracutaneous sites and reduced melanoma risk

Fewer cases of melanoma were observed in people with a history of atopic diseases, such as allergic asthma or rhinitis, than in nonatopic people.

6 Mar 2023

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

The immunosuppressive drug methotrexate (MTX) can be linked to an elevated risk of three types of skin cancer, a new study by University of Gothenburg researchers shows.

7 Feb 2023

Study finds fewer cases of melanoma among regular users of vitamin D supplements

Fewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds.

9 Jan 2023

The potential of grape consumption to modulate UV-induced skin erythema

A recent Antioxidants study evaluated the effect of grape consumption on reducing UV-induced skin erythema.

2 Dec 2022

Novel skin imaging technology improves the accuracy of basal cell carcinoma diagnosis

A novel imaging technique significantly improves the accuracy of the diagnosis of basal cell carcinoma (BCC) – the most frequent skin cancer – compared to clinical and dermoscopic examinations alone, according to new research being presented at the 31st European Academy of Dermatology and Venereology Congress.

7 Sep 2022

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

Patients treated for Merkel cell carcinoma (MCC) face a five-year recurrence rate of 40%-;markedly higher than the recurrence rates for melanoma and other skin cancers, according to research published today in JAMA Dermatology.

23 Feb 2022

UCLA-developed new "virtual histology" technology may reduce need for skin biopsies

Instead of surgically removing a sample of skin, sending it to a lab and waiting several days for results, your dermatologist takes pictures of a suspicious-looking lesion and quickly produces a detailed, microscopic image of the skin.

18 Nov 2021

Portable PDT device could pave the way for at-home treatment of basal cell carcinoma

A new prototype photodynamic therapy (PDT) device that can be used at home significantly reduces pain levels during treatment of basal cell carcinoma (BCC), while achieving efficacy comparable with a hospital stay. These findings come from a breakthrough pilot study, presented today at the 30th EADV Congress.

1 Oct 2021

Alcohol consumption increases risk of several cancers while coffee protects against liver, skin cancer

Alcohol consumption is a major risk factor for several cancers including head & neck, oesophageal and bowel cancer – as well as the more widely known links to breast and liver cancer – according to a new study funded by World Cancer Research Fund, and published this week in Nature Communications.

11 Aug 2021

Topical cream shows signs of clinical efficacy in patients with basal cell carcinoma

Remetinostat, a topical cream and first-in-class inhibitor of histone deacetylation, showed signs of clinical efficacy in patients with basal cell carcinoma.

6 Aug 2021