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Study links blast-related brain injuries in veterans to early Alzheimer's markers

U.S. veterans of the wars in Afghanistan and Iraq who suffered mild traumatic brain injury from exposure to explosive blasts were found to have changes in cerebrospinal fluid proteins that are typically seen in people who develop Alzheimer's disease, according to researchers at the University of Washington School of Medicine and VA Puget Sound Health Care System.

13 Mar 2024

Researchers discover mechanism to reverse amyloid plaque assembly in Alzheimer's disease

University of North Carolina at Chapel Hill researchers have developed a new drug delivery platform that harnesses helical amyloid fibers designed to untwist and release drugs in response to body temperatures.

22 Feb 2024

Ultra-high resolution MRI scanner offers new opportunities for brain research

An intense international effort to improve the resolution of magnetic resonance imaging (MRI) for studying the human brain has culminated in an ultra-high resolution 7 Tesla scanner that records up to 10 times more detail than current 7T scanners and over 50 times more detail than current 3T scanners, the mainstay of most hospitals.

27 Nov 2023

Advances in understanding and detecting Alzheimer's disease

Researchers are making strides toward understanding and detecting Alzheimer's disease in its earliest stages, when interventions may be most effective at slowing the progress of the disease.

13 Nov 2023

Reducing air pollution associated with lower risk of all-cause dementia and Alzheimer's disease

Previous reports have linked long-term air pollution exposure with accumulation of Alzheimer's disease-related brain plaques, but this is the first accumulated evidence that reducing pollution, especially fine particulates in the air and pollutants from the burning of fuel, is associated with lower risk of all-cause dementia and Alzheimer's disease.

27 Oct 2023

Research links hypertensive disorders of pregnancy with dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

28 Aug 2023

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

In the ongoing search for a cure for Alzheimer's disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system.

9 Aug 2023

Gut bacteria may play a role in cognitive decline

Two additional studies define specific gut bacteria that are associated with increased dementia risk, as well as gut bacteria that may be neuroprotective.

19 Jul 2023

Donanemab may offer new hope for people with early Alzheimer's disease

The data reported today by Eli Lilly from the TRAILBLAZER-ALZ 2 clinical trial of donanemab in early symptomatic Alzheimer's disease demonstrate an important advancement in Alzheimer's research and treatment.

17 Jul 2023

Major funding boost for research on neurodegenerative diseases

Brain Canada and the Canadian Institutes of Health Research congratulate Dr. Meaghan O'Reilly from Sunnybrook Research Institute and the University of Toronto as well as Dr. Liang Li based out of University of Alberta whose projects have been recommended for funding as part the 2022 European Union Joint Programme on Neurodegenerative Disease Research (JPND)'s initiative to find causes, develop cures and identify better ways to care for people with Alzheimer's, Parkinson's, Huntington's and other neurodegenerative diseases more rapidly.

16 Feb 2023

Novel nuclear medicine imaging protocol cuts costs and radiation exposure for Alzheimer's patients

A novel nuclear medicine imaging protocol can take the place of two separate imaging scans for the evaluation of brain changes linked to cognitive impairment, cutting costs and radiation exposure for patients as well as providing them greater comfort.

8 Feb 2023

Blood-based markers could lead to earlier detection of Alzheimer's disease

Alzheimer's disease begins decades before any symptoms, such as memory loss, start to show. Consequently, early diagnosis increases the chances of slowing the disease down with drugs.

10 Jan 2023

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease.

26 Dec 2022

Quanterix’s Simoa® technology drives advances in Alzheimer’s disease research presented at 2022 Clinical Trials On Alzheimer’s Disease (CTAD) conference

Quanterix Corporation, a company fueling scientific discovery through ultrasensitive biomarker detection, today announced that its Simoa® technology has powered important advances in ongoing clinical trials for the treatment of Alzheimer’s disease (AD). The findings were presented at the 15th Clinical Trials on Alzheimer’s Disease (CTAD) conference held in San Francisco, CA from November 29 to December 2, 2022.

From Quanterix 12 Dec 2022

Activation of microglial cells can slow down Alzheimer's progression

The brain's big-eating immune cells can slow down the progression of Alzheimer's disease. This is shown by a study that is now published in Nature Aging.

29 Nov 2022

People with Alzheimer's disease can be identified before any symptoms appear

A large study led by Lund University in Sweden has shown that people with Alzheimer's disease can now be identified before they experience any symptoms.

11 Nov 2022

Green tea catechins and resveratrol display neuroprotective properties in Alzheimer's models

In a recent study published in the journal Free Radical Biology and Medicine, researchers screened for neuroprotective compounds against Alzheimer’s disease (AD).

3 Nov 2022

First-of-its-kind computer model simulates a clinical trial evaluating two Alzheimer’s drugs

An estimated 6.2 million Americans ages 65 and older are living with Alzheimer's disease. The national Alzheimer's Association predicts that number to grow to 13.8 million by 2060, barring the development of medical breakthroughs that would prevent, slow or cure the debilitating disease.

2 Nov 2022

Discovery could affect the search for new Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks.

25 Oct 2022

Low meal frequency is suggested to decrease Alzheimer’s disease risk

Researchers evaluated the associations between low meal frequency (LMF) and Alzheimer’s disease (AD).

24 Oct 2022