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Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein, the cause of "mad cow disease" or BSE, chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease in humans, which has long remained a mystery. [More]
Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

In research published online today in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles' heel shared by all known types of Ebola virus. [More]
Research could pave way for more effective and safer anti-epilepsy drugs

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications. [More]
Interactions between rare and common genetic variants may contribute to craniosynostosis

Interactions between rare and common genetic variants may contribute to craniosynostosis

During the first year of life, the human brain doubles in size, and continues growing through adolescence. [More]
Researchers use unique computational approach to identify promising drug leads for heart diseases

Researchers use unique computational approach to identify promising drug leads for heart diseases

Using a unique computational approach to rapidly sample, in millisecond time intervals, proteins in their natural state of gyrating, bobbing, and weaving, a research team from UC San Diego and Monash University in Australia has identified promising drug leads that may selectively combat heart disease, from arrhythmias to cardiac failure. [More]
HIF-2 inhibitors could be promising target to combat kidney cancer

HIF-2 inhibitors could be promising target to combat kidney cancer

A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found. [More]
Researchers describe how genetic mutations cause unnamed neurological disorder

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder. [More]
New discovery offers way to develop vaccine against highly infectious bacteria

New discovery offers way to develop vaccine against highly infectious bacteria

Biochemists at the University of California San Diego have uncovered patterns in the outer protein coat of group A Streptococcus that could finally lead to a vaccine against this highly infectious bacteria--responsible for more than 500,000 deaths a year, including toxic shock syndrome and necrotizing fasciitis or "flesh-eating disease." [More]
Research aims to understand how cell designs length, pattern of heparan sulphate chains

Research aims to understand how cell designs length, pattern of heparan sulphate chains

Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases. [More]
Using biomarkers to diagnose sepsis: an interview with Jordi Trafi

Using biomarkers to diagnose sepsis: an interview with Jordi Trafi

Sepsis, according to the new clinical definition of sepsis, is organ dysfunction caused by the body’s dysregulated response to an infection. Sepsis is common, with about 20 million patients/year in the developed world. It can escalate to septic shock, which is a life-threatening condition with a mortality rate of about 40%. In fact, about every second someone in the world dies of sepsis. [More]
Breakthrough research on radioactive element could lead to new weapon against cancer

Breakthrough research on radioactive element could lead to new weapon against cancer

A new weapon against cancer could be just around the corner now that a Cal Poly Pomona professor and her colleagues from Stanford, Cornell and Los Alamos National Laboratory have unlocked some of the secrets of a fickle radioactive element. [More]
Research findings of protein may form foundation for new approach to antibiotics

Research findings of protein may form foundation for new approach to antibiotics

Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics. [More]
Scientists combine immunotherapy with chemotherapy to eliminate cancer recurrence

Scientists combine immunotherapy with chemotherapy to eliminate cancer recurrence

Scientists from the United States have made an important step toward eliminating cancer recurrence by combining immunotherapy with chemotherapy. [More]
Texas Tech researcher examines how healthy brown fat can be activated in humans

Texas Tech researcher examines how healthy brown fat can be activated in humans

Come fall, being a bear starts to look better and better. They load up on fat, sleep the winter away and wake up hungry. [More]
WSU pharmacologists find hyperbaric oxygen therapy can alleviate opiate withdrawal symptoms

WSU pharmacologists find hyperbaric oxygen therapy can alleviate opiate withdrawal symptoms

Washington State University researchers have found that treatments of pure oxygen in a high-pressure chamber can relieve the symptoms of opiate withdrawal. [More]
University of Nebraska-Lincoln wins $11.3 million NIH grant to establish CIBC

University of Nebraska-Lincoln wins $11.3 million NIH grant to establish CIBC

The University of Nebraska-Lincoln has earned an $11.3 million grant from the National Institutes of Health to establish a research center focused on investigating cellular level miscommunications that contribute to complex diseases such as cancer, diabetes and chronic liver disease. [More]
Mitosis study identifies new potential target for cancer therapy

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy. [More]
Study shows how caffeine counteracts age-related cognitive deficits in animals

Study shows how caffeine counteracts age-related cognitive deficits in animals

A study published in the journal Scientific Reports from Nature publishing group, describes the mechanism by which caffeine counteracts age-related cognitive deficits in animals. [More]
New discovery could lead to effective treatment methods for cystitis

New discovery could lead to effective treatment methods for cystitis

Every year, millions of people are treated for cystitis, but despite its prevalence, the disease is still a scientific mystery. [More]
Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool. [More]
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