Biochemistry News and Research

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Blood chip could offer early insights into cancer treatment effectiveness

Using a chip to process blood samples, doctors can monitor the amount of cancer cells in a patient’s blood to determine how well a treatment is working by the fourth week, according to a new University of Michigan study.

29 Jan 2024

Immune component of breast milk shapes the gut environment of infant mice

An immune component of breast milk known as the complement system shapes the gut environment of infant mice in ways that make them less susceptible to certain disease-causing bacteria, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

24 Jan 2024

Aerobic exercise could help combat non-alcoholic fatty liver disease

According to a study conducted on animal models and published in the journal Metabolism, aerobic exercise could help fight the non-alcoholic fatty liver disease, the most common liver disease worldwide: it affects nearly 24% of the global population and it usually causes a certain stigma among the affected people.

22 Jan 2024

DNA origami used to unveil novel Notch receptor activation pathway

Researchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way.

18 Jan 2024

New targeted therapy eliminates cancer with zero side effects

Johannes Karges develops anti-cancer agents that work in a targeted manner, rather than adversely affecting the entire body.

18 Jan 2024

New USC study reveals how DNA loops silence gene activity

The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not random.

16 Jan 2024

Unlocking protein secrets: X-ray crystallography reveals hidden shapes

Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks.

12 Jan 2024

CZI grant backs groundbreaking research on bystander cells in disease spread

Researchers examining disease infection in bystander cells, which are next to infected cells but are not infected themselves, following antimicrobial treatment, were granted nearly $500,000 from the Chan Zuckerberg Initiative to advance their work.

11 Jan 2024

Study: Respiratory syncytial virus directly infects nerve cells and causes inflammation

Respiratory syncytial virus (RSV), a common infection in children and senior adults, can also infect nerve cells and trigger inflammation leading to nerve damage, according to a new Tulane University study.

10 Jan 2024

Nasal drops with IgA antibodies may protect against COVID-19 and future variants

Researchers at Karolinska Institutet in Sweden have shown that nasal drops with IgA antibodies can protect mice from SARS-CoV-2 infection.

10 Jan 2024

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.

3 Jan 2024

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

A team of Virginia Tech researchers was awarded nearly $2 million from the National Institute of Diabetes and Digestive and Kidney Disease, part of the National Institutes of Health, to explore novel approaches for treating Type 2 diabetes and obesity.

3 Jan 2024

Researchers identify microbial enzyme responsible for making urine yellow

Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology on January 3, 2024.

3 Jan 2024

Understanding acylspermidines' secrets could lead to treatments for various diseases

In a significant advancement in the field of biochemistry, scientists at the Boyce Thompson Institute (BTI) and Cornell University have uncovered new insights into a family of metabolites, acylspermidines, that could change how we understand aging and fight diseases.

2 Jan 2024

New family of polymers can kill bacteria without inducing antibiotic resistance

Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention.

22 Dec 2023

St. Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

22 Dec 2023

Protein "on/off switch" controls breast cancer spread and immunotherapy response

Despite their promise, immunotherapies fail to treat many cancers, including over 80% of some of the most advanced breast cancers.

20 Dec 2023

TMDU researchers develop novel method to identify protein-protein binding interfaces

Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going.

20 Dec 2023

Biochemistry News and Research

Blood chip could offer early insights into cancer treatment effectiveness

Immune component of breast milk shapes the gut environment of infant mice

Aerobic exercise could help combat non-alcoholic fatty liver disease

DNA origami used to unveil novel Notch receptor activation pathway

New targeted therapy eliminates cancer with zero side effects

New USC study reveals how DNA loops silence gene activity

Unlocking protein secrets: X-ray crystallography reveals hidden shapes

CZI grant backs groundbreaking research on bystander cells in disease spread

Study: Respiratory syncytial virus directly infects nerve cells and causes inflammation

Nasal drops with IgA antibodies may protect against COVID-19 and future variants

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Unmasking the persistent threats of long-COVID's pulmonary sequelae

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

Researchers identify microbial enzyme responsible for making urine yellow

Understanding acylspermidines' secrets could lead to treatments for various diseases

New family of polymers can kill bacteria without inducing antibiotic resistance

St. Jude researchers crack the code of the β2-adrenergic receptor

Protein "on/off switch" controls breast cancer spread and immunotherapy response

TMDU researchers develop novel method to identify protein-protein binding interfaces

Biochemistry eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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