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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer

Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer

Researchers at Mayo Clinic Center for Individualized Medicine have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy. [More]
Music lessons increase brain fiber connections in children

Music lessons increase brain fiber connections in children

Taking music lessons increases brain fiber connections in children and may be useful in treating autism and Attention Deficit Hyperactivity Disorder (ADHD), according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA). [More]
Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment

Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment

Immunotherapy continues to revolutionize the field of non-small cell lung cancer (NSCLC), with researchers now focusing on the optimal use of immune agents in the frontline setting. [More]
BAG3 protein plays protective role by limiting reperfusion injury to the heart

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle. [More]
Purdue University biochemist develops novel method for identifying cancer biomarkers

Purdue University biochemist develops novel method for identifying cancer biomarkers

A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases. [More]
How toxic is your stress?

How toxic is your stress?

The term “stress” originates not in our minds or bodies, but from physics. It is the internal forces generated in an object in response to an external load. In the 1950s, Hans Selye adopted the term to characterize how living organisms change... [More]
Researchers identify new biomarker in spinal fluid and blood serum of patients with neurological disorder

Researchers identify new biomarker in spinal fluid and blood serum of patients with neurological disorder

Research from Mayo Clinic included in the November issue of JAMA Neurology identifies a new biomarker for brain and spinal cord inflammation, allowing for faster diagnosis and treatment of patients. [More]
NSU researchers learn more about Gulf War illness to help veterans

NSU researchers learn more about Gulf War illness to help veterans

As the nation honors our veterans on November 11, we must pause to remember the long-lasting health effects soldiers experience not only from bullets or bombs, but from exposure to unexplained pesticides, radiation or other toxins during their time in the service. [More]
Neuroimaging markers may help predict psychotherapy response in patients with depression, anxiety

Neuroimaging markers may help predict psychotherapy response in patients with depression, anxiety

Brain imaging scans may one day provide useful information on the response to psychotherapy in patients with depression or anxiety, according to a review of current research in the November/December issue of the Harvard Review of Psychiatry, published by Wolters Kluwer. [More]
Researchers develop new blood test that can accurately diagnose concussions

Researchers develop new blood test that can accurately diagnose concussions

Scientists from Children's Health Research Institute, a program of Lawson Health Research Institute, and Western University have developed a new blood test that identifies with greater than 90 per cent certainty whether or not an adolescent athlete has suffered a concussion. [More]
Study explores biological marker to predict individual response to drug treatment for combat PTSD

Study explores biological marker to predict individual response to drug treatment for combat PTSD

Treatment with the drug prazosin effectively reduces symptoms of posttraumatic stress disorder (PTSD) for many people, but about one third of patients don't respond to the treatment at all. [More]
Brain inflammation may have direct involvement in development of chronic traumatic encephalopathy

Brain inflammation may have direct involvement in development of chronic traumatic encephalopathy

For the first time, researchers have shown that inflammation in the brain may have direct involvement in the development of chronic traumatic encephalopathy (CTE). In addition, they found that the number of years one plays contact sports may predict the occurrence of CTE and that this association is partly due to increased inflammation in the brain. [More]
New study to explore impact of vitamin K supplement on cardiovascular health of obese children

New study to explore impact of vitamin K supplement on cardiovascular health of obese children

Researchers want to know whether a vitamin K supplement is an effective, inexpensive way to help reduce the cardiovascular risk of obese children. [More]
Myriad Genetics presents research data that validates accuracy of myPath Melanoma test

Myriad Genetics presents research data that validates accuracy of myPath Melanoma test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced it will present two new studies at the American Society of Dermatopathology (ASDP) annual meeting being held Oct. 27-30, 2016 in Chicago, Ill. [More]
Study shows physicians in pediatric ICUs do not use newest guidelines to diagnose AKI in children

Study shows physicians in pediatric ICUs do not use newest guidelines to diagnose AKI in children

A study by University at Buffalo researchers has shown that physicians in pediatric intensive care units are not using the newest guidelines to diagnose acute kidney injury (AKI) in critically ill children, a practice that could affect their patients' long-term health. [More]
Breakthrough research paves way for developing new asthma treatments

Breakthrough research paves way for developing new asthma treatments

'The study demonstrated for the first time that a protein called PP5 was significantly upregulated in the lungs of severe asthmatic patients compared to healthy controls. We are extremely excited by this paradigm shift observation.' - Dr Yassine Amrani, University of Leicester. [More]
New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

A blood test that has shown promise in predicting how cancer will progress and what treatments will be most effective for a given patient may not be reliable for either, according to a new Penn Medicine study published this week in Cancer, a peer-reviewed journal of the American Cancer Society. [More]
Novel approach to analyzing brain structures may help predict progression of Alzheimer's disease

Novel approach to analyzing brain structures may help predict progression of Alzheimer's disease

Use of a novel approach to analyzing brain structure that focuses on the shape rather than the size of particular features may allow identification of individuals in early presymptomatic stages of Alzheimer's disease. [More]
Immunotherapy drug approved by FDA as first-line treatment for non-small cell lung cancer

Immunotherapy drug approved by FDA as first-line treatment for non-small cell lung cancer

Pembrolizumab, an immunotherapy drug that was extensively evaluated by UCLA cancer researcher Dr. Edward Garon, has been approved by the U.S. Food & Drug Administration as first-line treatment for non-small cell lung cancer (NSCLC). [More]
Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Tumor cells collected during the removal of a cancerous bladder and - in some cases - transplanted into mice with weakened immune systems, could help physicians rapidly identify high-risk cancers, determine prognosis and refine the use of biomarkers to personalize care for patients with this common cancer, according to a study published online on Oct. 24, 2016, in Scientific Reports. [More]
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