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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
New technique can help identify aggressive forms of DCIS

New technique can help identify aggressive forms of DCIS

When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful? [More]
Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD

Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD

Regular consumption of seafood and plant-based omega-3 polyunsaturated fatty acids could help lower the risk of fatal coronary heart disease, confirm findings from a pooled analysis of 19 studies. [More]
Home test using paper strips could help detect cancer, malaria

Home test using paper strips could help detect cancer, malaria

What if testing yourself for cancer or other diseases were as easy as testing your blood sugar or taking a home pregnancy test? In a few years, it might be. [More]
Non-invasive fluid-based biomarker could help identify aggressive prostate cancer before surgery

Non-invasive fluid-based biomarker could help identify aggressive prostate cancer before surgery

Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery. [More]
Blood mannose levels could help predict type 2 diabetes risk

Blood mannose levels could help predict type 2 diabetes risk

Even if you are not overweight, your mannose levels may indicate whether you're at risk for type 2 diabetes (T2D) or insulin resistance (IR), a Swedish study shows. [More]
Stony Brook researcher receives grant to evaluate daily activity levels, heart rate patterns of CFS patients

Stony Brook researcher receives grant to evaluate daily activity levels, heart rate patterns of CFS patients

By better understanding daily activity levels and heart rate patterns of those who suffer from Chronic Fatigue Syndrome (CFS), scientists hope to discover more about this complex illness condition. [More]
Protein-based CHD risk score developed

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease. [More]
Potential therapeutic approaches to combat chronic myeloid leukemia

Potential therapeutic approaches to combat chronic myeloid leukemia

Chronic myeloid leukemia (CML) develops through chromosomal alterations in blood-forming cells of the bone marrow and usually occurs in older persons. Around 20 percent of adults diagnosed with leukemia suffer from this type of blood cancer. [More]
Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how. [More]
E-cigarette use modifies gene expression important for upper airway immune defense

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation. [More]
Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Mothers of children with autism and were diagnosed with metabolic conditions during pregnancy, particularly gestational and type 2 diabetes, were more likely to have anti-fetal brain autoantibodies in their blood compared to healthy women of children with autism. [More]
ERCC2 validated as chemotherapy response biomarker in bladder cancer

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Somatic mutations in the helicase-encoding ERCC2 gene are associated with response to neoadjuvant cisplatin-based chemotherapy in patients with muscle-invasive urothelial bladder carcinoma. [More]
Study finds link between chronic inflammation and premenstrual symptoms

Study finds link between chronic inflammation and premenstrual symptoms

Women with premenstrual symptoms (PMS) including mood swings, weight gain/bloating, and abdominal cramps/back pain have elevated levels of C-reactive protein (CRP), a biomarker of inflammation associated with increased risk of cardiovascular disease. [More]
New superbug test developed by TGen-NAU receives Australian patent

New superbug test developed by TGen-NAU receives Australian patent

Antibiotic-resistant infections should be easier to detect, and hospitals could become safer, thanks to a technology developed by the Translational Genomics Research Institute and Northern Arizona University, and protected under a patent issued by Australia. [More]
Potential non-invasive screening biomarker for SSc-PAH

Potential non-invasive screening biomarker for SSc-PAH

Serum asymmetric dimethylarginine may be an effective non-invasive screening biomarker for systemic sclerosis-related pulmonary arterial hypertension, study findings indicate. [More]
Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Mayo researchers develop extremely precise assay to measure age-associated changes in GDF11

Researchers at Mayo Clinic have developed an accurate way to measure a circulating factor, called GDF11, to better understand its potential impact on the aging process. [More]
FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system. [More]
PET imaging can help identify autoimmune inflammation in MS

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging. [More]
Anti-TNF therapy offers new hope to JDM patients

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM). [More]
Advanced imaging technique helps predict recovery in concussion patients

Advanced imaging technique helps predict recovery in concussion patients

Using an advanced imaging technique, researchers at Albert Einstein College of Medicine and Montefiore Health System were able to predict which patients who'd recently suffered concussions were likely to fully recover. [More]
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