Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Proteomic signatures in blood plasma and cervicovaginal fluid for endometrial cancer detection.

26 Mar 2024

MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

25 Mar 2024

Study reveals breakthrough in non-invasive detection of endometrial cancer

Study uncovers proteomic signatures in blood plasma and cervicovaginal fluid that could lead to non-invasive detection methods for endometrial cancer, demonstrating significant potential for early diagnosis and improved patient outcomes.

24 Mar 2024

Biomechanical model simulates breast tumor growth

Scientists from Universidad Carlos III de Madrid (UC3M) and Johns Hopkins University (JHU), in the USA, have analyzed the growth of breast tumors from a biomechanical perspective and have created a computational model that simulates the invasion process of cancer cells, depending on the characteristics of the surrounding tissue and cell junctions, among other parameters.

21 Mar 2024

Researchers develop AI tool to predict side effects of treatment in breast cancer patients

A team of international researchers have developed an artificial intelligence (AI) tool that can predict which breast cancer patients may be at risk of side effects after surgery and radiotherapy.

21 Mar 2024

Skin biopsy test shows promise in diagnosing Parkinson's disease and synucleinopathies

In a paper published in the Journal of the American Medical Association (JAMA), neurologists at Beth Israel Deaconess Medical Center (BIDMC) showed that a simple skin biopsy test detects an abnormal form of alpha-synuclein, the pathological hallmark of Parkinson's disease and the subgroup of neurodegenerative disorders known as synucleinopathies, at high positivity rates.

20 Mar 2024

New insights into upper tract urothelial carcinoma evolution and treatment

Researchers at Weill Cornell Medicine have performed the most comprehensive analysis to date of cancer of the ureters or the urine-collection cavities in the kidney, known as upper tract urothelial carcinoma (UTUC).

18 Mar 2024

Implantable temperature sensor detects inflammatory flareups in patients with Crohn's disease

A team of Northwestern University scientists has developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease.

18 Mar 2024

Cedars-Sinai expert explains new treatment options for pediatric patients with sarcomas

Leo Mascarenhas, MD, MS, has an important message for parents whose children have been diagnosed with sarcoma, a type of cancer that develops in the bones or soft tissues.

14 Mar 2024

Blood test shows 83% accuracy in detecting colorectal cancer

A blood test intended for screening for colorectal cancer in people who are of average risk and not experiencing symptoms correctly detected colorectal cancer in 83% of people confirmed to have the disease, according to a study published March 14 in the New England Journal of Medicine.

13 Mar 2024

AI method can predict brain metastasis in lung cancer patients

Physicians treating patients with early-stage lung cancer face a conundrum: choosing potentially helpful yet toxic therapies such as chemotherapy, radiation or immunotherapy to knock out the cancer and lessen the risk of it spreading to the brain, or waiting to see if lung surgery alone proves sufficient.

11 Mar 2024

Revolutionizing prostate cancer diagnostics with 3D pathology and deep learning

Prostate cancer stands as a prevalent threat to men's health, ranking second in cancer-related deaths in the United States.

11 Mar 2024

Breakthrough nanopipette enables real-time observation of cancer cell reactions to treatment

The high-tech double-barrel nanopipette, developed by University of Leeds scientists, and applied to the global medical challenge of cancer, has - for the first time - enabled researchers to see how individual living cancer cells react to treatment and change over time – providing vital understanding that could help doctors develop more effective cancer medication.

6 Mar 2024

Harnessing repetitive DNA for early cancer detection

People with cancer have different amounts of a type of repetitive DNA -; called Alu elements -; than people without cancer.

4 Mar 2024

Researchers discover a noninvasive, low-cost test to detect oral cancer

Oral cancers and precancerous mouth lesions are considered especially difficult to diagnose early and accurately.

4 Mar 2024

Common prostate cancer test may leave black men at increased risk of overdiagnosis

A new study from experts at the University of Exeter has found that a widely used test for prostate cancer may leave black men at increased risk of overdiagnosis.

29 Feb 2024

Breakthrough blood test developed for early detection of sarcoidosis

A research project led by Lobelia Samavati, M.D., professor of internal medicine and molecular medicine and genetics at the Wayne State University School of Medicine, and supported by the National Institutes of Health (NIH), has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs.

28 Feb 2024

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Breakthrough research could transform the landscape of ovarian cancer treatment

In a major scientific breakthrough, newly published research from an international consortium led by the University of Minnesota's Masonic Cancer Center has the potential to transform the landscape of ovarian cancer treatment.

27 Feb 2024

Cedars-Sinai researchers discover why some injured kidneys heal while others develop scarring

Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure.

22 Feb 2024