A paper published this month in the prestigious medical journal The Lancet Neurology suggests that a broad spectrum of developmental and psychiatric disorders, ranging from autism and intellectual disability to schizophrenia, should be conceptualized as different manifestations of a common underlying denominator, "developmental brain dysfunction," rather than completely independent conditions with distinct causes.
[More]
Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body - with an eye to developing a safer alternative.
[More]
Through a program that teaches simple nutrition messages and involves both counseling and regular exercise classes, people with serious mental illness can make healthy behavioral changes and achieve significant weight loss, according to new Johns Hopkins research.
[More]
Through a program that teaches simple nutrition messages and involves both counseling and regular exercise classes, people with serious mental illness can make healthy behavioral changes and achieve significant weight loss, according to new Johns Hopkins research.
[More]
The American Physiological Society is one of six scientific societies sponsoring the meeting Experimental Biology 2013, being held April 20-24, 2013 at the Boston Convention and Exhibition Center, in Boston, Mass.
[More]
A surprisingly high number of women have postpartum depressive symptoms, according to a new, large-scale study by a Northwestern Medicine- researcher.
[More]
Gamma-aminobutyric acid (GABA) deficits have been implicated in schizophrenia and depression. In schizophrenia, deficits have been particularly well-described for a subtype of GABA neuron, the parvalbumin fast-spiking interneurons.
[More]
Researchers have found increased cellular expression of the postsynaptic signaling protein AKAP5/79 in the anterior cingulate cortex of patients with bipolar disorder.
[More]
A study published in the February 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that children and adolescents with major depression or subthreshold forms of bipolar disorder - and who had at least one first-degree relative with bipolar disorder - responded better to a 12-session family-focused treatment than to a briefer educational treatment.
[More]
Children born to families where at least one parent has bipolar disorder do not show abnormalities in attachment compared with other children, say Canadian researchers.
[More]
Determining the androgen content in prostate tissue could predict patients’ responses to androgen deprivation therapy and the risk for castration-resistant prostate cancer, show study findings.
[More]
Patients with bipolar disorder have relatively greater impairments in non-social cognition than social cognition, whereas the opposite is true for patients with schizophrenia, researchers report.
[More]
People with bipolar I disorder tend to be aware of the potential for goal achievement to trigger mania and as a result dampen their emotions and avoid reward, preliminary research suggests.
[More]
Increased appetite, sleep, and weight gain, among other clinical features, can be used to help identify patients with bipolar disorder who have been misdiagnosed with major depressive disorder.
[More]
Androgen deprivation therapy for prostate cancer hampers glycemic control in men with diabetes, report researchers.
[More]
Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis. The study, which is published in the scientific periodical Molecular Psychiatry, identifies a gene variant associated with an increased production of KYNA.
[More]
Taiwanese individuals with bipolar disorder are at an increased risk for hypertension when compared with the general population, research shows.
[More]
For the first time, scientists have discovered that five major psychiatric disorders—autism, attention deficit-hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder and schizophrenia—share several common genetic risk factors.
[More]
Researchers have used an original proteomic strategy to identify a biomarker for residual spermatogenesis in the semen of patients with nonobstructive azoospermia (NOA).
[More]