Blastocyst News and Research

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Understanding the mechanisms behind embryonic diapause in hungry mouse mums

It's challenging to sustain a pregnancy when food is short, or conditions are otherwise tough. That's why many mammalian embryos can postpone their growth to get through periods of environmental stress and then re-enter development when conditions improve.

12 Apr 2024

New study reveals lifestyle factors boosting IVF success

Study investigates the complex relationships between lifestyle choices, fertility-specific quality of life, and the success rates of assisted reproductive technology treatments, offering valuable insights for couples undergoing these treatments.

10 Apr 2024

Unlocking the mysteries of early human development through blastoid models

It's one of life's most defining moments-;that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for all to come.

22 Mar 2024

New study brings us closer to growing replacement lungs for patients

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. It is marked by lung damage that is lasting and incurable, leaving lung transplantation as the only viable treatment option.

5 Jan 2024

Early embryo DNA replication program reveals unexpected flexibility

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next.

20 Dec 2023

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

A new study published in Nature Medicine reports on a chromosomal analysis of over 1,700 spontaneous early miscarriages.

27 Nov 2023

New rapid test for sperm damage may predict embryonic aneuploidy and improve reproductive outcomes

A rapid diagnostic method for double-strand breaks (DSBs), Sperm deoxyribonucleic acid (DNA) Fragmentation (SDF) Releasing Assay (SDFR).

7 Nov 2023

Optimized protocol to prevent disease transmission through maternal mitochondrial DNA carryover

Researchers discuss a novel technique to minimize the risk of mtDNA carryover, thereby preventing genetic risk and clinical mitochondrial disease.

5 Oct 2023

Researchers create "synthetic embryos" from bovine pluripotent stem cells

An article published in the journal Cell Stem Cell describes the first scientific study to develop blastoids – "synthetic embryos", as they were initially (and incorrectly) called – from bovine pluripotent stem cells (PSCs).

26 Jul 2023

Generating functional parathyroid glands from mouse embryonic stem cells

Regenerative medicine has opened up exciting possibilities in the world of medicine. Now, researchers in Japan are searching for ways to recreate and rebuild body tissues and organs, which may be an alternative cure for diseases.

24 Jul 2023

Research reveals molecular features of rare mtDNA mutations

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

13 Apr 2023

Magnetic microrobot probe can quantify the stiffness and traction forces of cell colonies and embryos in vivo

In a recent study published in the journal Science Robotics, a team of researchers created a magnetic microrobot probe that can quantify the stiffness and traction force of tumor cell colonies and developing vertebrate embryos.

29 Jan 2023

Microbiomes in female reproductive tract linked to pregnancy following use of ART

Specific microbial profiles are associated with better conception rates from assisted reproductive technology.

9 Dec 2022

Researchers demonstrate improved culture of primate induced pluripotent stem cells

The following study transplanted iPSCs derived from two NHP species, chimpanzee and pigtailed macaque, into blastocysts from another NHP species – the rhesus macaque.

1 Sep 2022

IMBA researchers uncover basic principles of early development using blastoids

One often thinks that the early embryo is fragile and needs support. However, at the earliest stages of development, it has the power to feed the future placenta and instructs the uterus so that it can nest.

7 Jul 2022

Does COVID-19 vaccination affect IVF treatments?

A new study assesses the impact of COVID-19 vaccination in women undergoing assisted reproduction.

12 Apr 2022

BGI discovery could pave the way for advances in organ regeneration and synthetic biology

In a world-first, scientists from BGI-Research, Chinese Academy of Sciences, and a group of partners published a study in Nature, announcing the discovery of a transgene-free, rapid, and controllable method to convert pluripotent stem-cells into bona fide 8-cell totipotent embryo-like cells, paving the way for advances in organ regeneration and synthetic biology.

22 Mar 2022