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Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.
NR supplements can reduce diabetes-related complications in mice

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System. [More]
HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

A retrospective review of medical records found the HbA1C test, commonly used to diagnose and manage diabetes, can effectively detect hidden disease among hospital patients with hyperglycemia, commonly known as high blood sugar. [More]
Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition. [More]
Exposure to bright light may influence metabolism

Exposure to bright light may influence metabolism

Exposure to bright light could affect your metabolism, reports a new Northwestern Medicine study. [More]
UD scientists merge electronic health records to improve care, clinical outcomes for CKD patients

UD scientists merge electronic health records to improve care, clinical outcomes for CKD patients

Electronic health records have the potential to reduce the incidence of medical errors, duplication of tests, and delays in treatment. [More]
Clinical study shows sitagliptin drug not effective in treating NAFLD

Clinical study shows sitagliptin drug not effective in treating NAFLD

A diabetes medication described in some studies as an effective treatment for nonalcoholic fatty liver disease (NAFLD) works no better than a placebo, report researchers at University of California San Diego School of Medicine, after conducting the first randomized, double-blind, controlled clinical trial of sitagliptin, an oral antihyperglycemic marketed by Merck & Co. under the name Januvia. [More]
Comprehensive genomic characterizations of ACC provide potentially better treatment options

Comprehensive genomic characterizations of ACC provide potentially better treatment options

An international team of scientists, including those at the Translational Genomic Research Institute (TGen), have discovered new avenues of potential treatments for a rare and deadly cancer known as Adrenocortical Carcinoma, or ACC. [More]
Researchers produce insulin-secreting cells from stem cells of diabetic patients

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes. [More]
Digital health: putting patients at the center. An interview with Roz Davies

Digital health: putting patients at the center. An interview with Roz Davies

In England alone the NHS sees 1 million patients every 36 hours and there are 3 million volunteers across health and social care many of whom are motivated by their personal experience of healthcare services. [More]
Food deprivation may help treat fatty liver disease

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver. [More]
Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

University of Toronto Assistant Professor of Pharmacy Keith Pardee and an international team of collaborators, including scientists from the Wyss Institute at Harvard University, have developed a low-cost, easy-to-use diagnostic platform for detecting the Zika virus. [More]
LifeBridge Health study to explore potential benefits of wireless heart monitoring system

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

The LifeBridge Health Cardiovascular Institute has launched a pilot study to evaluate the potential benefits of a wireless heart monitoring system for patients with moderate to severe heart failure. The system tracks weight, blood pressure and other measures, and automatically sends the information to doctors and staff at the Cardiovascular Institute. The study is looking at whether this approach, designed to be simple and easy-to-use, can result in better outcomes for patients with heart failure. [More]
Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Transplanted human islets provide excellent glycemic control for Type 1 diabetes patients with severe hypoglycemia

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. The results of the multi-center, single arm, phase III study are published in Diabetes Care on Monday, April 18. The research was funded by National Institute of Health grants through the National Institute of Allergy and Infectious Diseases and the National Institute for Diabetes and Digestive and Kidney Disease. [More]
Study helps discover new treatments for type 2 diabetes in men with low testosterone

Study helps discover new treatments for type 2 diabetes in men with low testosterone

Doctors have long known that men with low testosterone are at greater risk for developing type 2 diabetes. For the first time, researchers have identified how testosterone helps men regulate blood sugar by triggering key signaling mechanisms in islets, clusters of cells within the pancreas that produce insulin. The findings, co-authored by Tulane University researchers, are published in the journal [More]
Study links age-related changes in human pancreas to diabetes development

Study links age-related changes in human pancreas to diabetes development

A Stanford-led national collaboration to procure and analyze human pancreatic tissue from deceased donors illustrates how the organ's function changes as we age, and could point the way toward new diabetes treatments. [More]
Clinical inertia puts Type 2 diabetes patients at further risk of preventable complications

Clinical inertia puts Type 2 diabetes patients at further risk of preventable complications

People with Type 2 diabetes are being 'let down' because they are being forced to wait for further treatment when needed. [More]
Scientists uncover molecular identity of previously unknown Glima molecule in Type 1 diabetes

Scientists uncover molecular identity of previously unknown Glima molecule in Type 1 diabetes

Scientists have solved a decades-old medical mystery by finally identifying a previously unknown molecule which is attacked by the immune system in people with Type 1 diabetes. [More]
Artificial intelligence in healthcare: an interview with Dr Ehud Reiter

Artificial intelligence in healthcare: an interview with Dr Ehud Reiter

Artificial Intelligence has made huge advances in recent years in many areas, including language processing, vision, and machine learning; we are also seeing the emergence of platforms that integrate different kinds of AI, such as IBM Watson (Arria is a Watson ecosystem partner). [More]
Study points to novel way to treat diabetes in some patients

Study points to novel way to treat diabetes in some patients

Blocking the hormone that raises sugar levels in the blood could increase insulin levels while keeping blood sugar levels down. [More]
Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Transplanted human islets prevent hypoglycemic events in Type 1 diabetes patients

Northwestern Medicine researchers are co-investigators in a breakthrough clinical trial that found transplanted human islets prevent hypoglycemic events and provide excellent glycemic control for patients with Type 1 diabetes with severe hypoglycemia. [More]
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