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Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.
Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

The incidence of a potentially life-threatening complication of diabetes, diabetic ketoacidosis, in youth in Colorado at the time of diagnosis of type 1 diabetes increased by 55 percent between 1998 and 2012, suggesting a growing number of youth may experience delays in diagnosis and treatment, according to a study in the April 21 issue of JAMA, a theme issue on child health. [More]
New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins. [More]
UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

UC Davis Assistant Professor Mark Huising is a recipient of The Hartwell Foundation 2014 Individual Biomedical Research Award to support his early-stage research toward a cure for juvenile diabetes. Diabetes affects 10 percent of the entire United States population, including approximately a million children. Remarkably, 40 children every day receive the diagnosis of diabetes. [More]
CPAP use reduces atrial fibrillation recurrence in patients with obstructive sleep apnea

CPAP use reduces atrial fibrillation recurrence in patients with obstructive sleep apnea

The use of continuous positive airway pressure was associated with a significant reduction in the recurrence of atrial fibrillation in patients with obstructive sleep apnea, according to an analysis of data from past research published today in the Journal of the American College of Cardiology: Clinical Electrophysiology. [More]
Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai Inc. and Arena Pharmaceuticals, Inc. today announced the completion of two Phase 1 registrational clinical trials that Eisai and Arena believe demonstrate bioequivalence of an investigational once-daily extended release formulation of lorcaserin, as compared to the twice-daily immediate release formulation approved by the US Food and Drug Administration and marketed as BELVIQ. [More]
Better insulin injection technique can improve blood glucose control in diabetes patients, says study

Better insulin injection technique can improve blood glucose control in diabetes patients, says study

A recent study by Grassi et al. has concluded that blood glucose control in diabetes patients who inject insulin can be improved through better injection technique, which includes switching patients to 4 mm pen needles. [More]
Commercial weight-loss programs can make significant difference in overall health

Commercial weight-loss programs can make significant difference in overall health

New research published in the Annals of Internal Medicine finds that commercial weight-loss programs can offer significant weight loss after one year of participation when compared to a control group. Researchers led by Kimberly A. Gudzune, M D, MPH, found that participants achieved up to 4.9% mean total weight loss following one year of participation, which could be medically significant for many people with obesity or excess weight. [More]
CUMC researchers identify cellular defect that could lead to potential new treatment for diabetes

CUMC researchers identify cellular defect that could lead to potential new treatment for diabetes

A cellular defect that can impair the body's ability to handle high glucose levels and could point the way to a potential new treatment for diabetes has been identified by Columbia University Medical Center researchers. [More]
Study identifies gut immune system as new, effective target for diabetes

Study identifies gut immune system as new, effective target for diabetes

A commonly-used drug to treat inflammatory bowel disease, such as Crohn's disease, has been shown to lower blood sugar levels in obese mice, potentially identifying the gut immune system as a new and effective target in treating diabetes in humans. [More]
Cardiovascular deaths continue to rise globally despite gains in prevention, treatment

Cardiovascular deaths continue to rise globally despite gains in prevention, treatment

As the global population pushes past 7 billion and more people reach old age, the number of deaths from cardiovascular diseases is on the rise. Cardiovascular diseases, the leading cause of premature death in the world, include heart attacks, strokes, and other circulatory diseases. [More]
CABG surgery improves long-term survival in diabetic patients with severe heart disease

CABG surgery improves long-term survival in diabetic patients with severe heart disease

Among diabetic patients with severe heart disease, coronary artery bypass grafting (CABG) surgery is better than stenting (percutaneous coronary intervention; PCI) at improving long-term survival and reducing the risk of adverse complications, according to an article in the April 2015 issue of The Annals of Thoracic Surgery. [More]
Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

RESEARCH-active members of the public are to showcase how their vital work helps shape clinical research projects and improves care for patients at a free drop-in event in Sheffield City Centre on Wednesday 22 April. [More]
Research reveals why people with type 1 diabetes are unable to control blood glucose levels

Research reveals why people with type 1 diabetes are unable to control blood glucose levels

TEACHING people with type 1 diabetes how to embed lifelong habits such as carbohydrate counting into everyday life rather than as part of week-long education programmes could significantly reduce their risk of complications from the disease, according to new research. [More]
Women who give birth to four or more children at risk of heart disease

Women who give birth to four or more children at risk of heart disease

Women who give birth to four or more children are more likely to have cardiovascular changes that can be early indicators of heart disease than women who have fewer children, new research by UT Southwestern Medical Center cardiologists finds. [More]
Glyxambi for Type 2 diabetes treatment now available by prescription across the U.S.

Glyxambi for Type 2 diabetes treatment now available by prescription across the U.S.

Glyxambi® (empagliflozin/linagliptin) tablets are now available by prescription in many leading chain and independent pharmacies across the U.S., including Walgreens and Rite Aid. [More]
TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Scientists from the Florida campus of The Scripps Research Institute have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease. [More]
Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

Sildenafil drug may effectively relieve nerve damage in men with long-term diabetes

New animal studies at Henry Ford Hospital found that sildenafil, a drug commonly used to treat erectile dysfunction, may be effective in relieving painful and potentially life-threatening nerve damage in men with long-term diabetes. [More]
TCC-EZ Casting System dramatically increases healing process of diabetic foot ulcers

TCC-EZ Casting System dramatically increases healing process of diabetic foot ulcers

Diabetics once facing the prospect of amputation to their lower limbs due to the effects of foot ulcers are now back on their feet thanks to a new technology. [More]
OSU engineers use 'additive manufacturing' to create glucose sensor for patients with diabetes

OSU engineers use 'additive manufacturing' to create glucose sensor for patients with diabetes

Engineers at Oregon State University have used "additive manufacturing" to create an improved type of glucose sensor for patients with Type 1diabetes, part of a system that should work better, cost less and be more comfortable for the patient. [More]
Active ingredient dextromethorphan may help people with Type 2 diabetes

Active ingredient dextromethorphan may help people with Type 2 diabetes

The active ingredient dextromethorphan, which is contained in many over-the-counter cough remedies, has been shown to improve blood sugar levels in type 2 diabetes (diabetes mellitus). That was the finding of a recent international study, in which the Center for Physiology and Pharmacology of MedUni Vienna played a significant part and which has now been published in the leading medical journal "Nature Medicine". [More]
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