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New genes associated with osteoarthritis progression

Scientists from University of North Carolina at Chapel Hill School of Medicine and Interleukin Genetics, Inc. announced today findings from a large clinical study to evaluate the role played by genetic factors in the worsening of osteoarthritis.

21 Sep 2010

FDA grants orphan drug designation for MultiStem stem cell therapy

Athersys, Inc. announced today that MultiStem, Athersys' multipotent adult progenitor stem cell therapy, has been granted orphan drug designation by the U. S. Food and Drug Administration for the prevention of graft vs. host disease (GvHD).

21 Sep 2010

Cytheris commences enrollment in CYT107 recombinant human Interleukin-7 clinical trial for HIV

Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced that it has begun enrolling patients in INSPIRE 3, a Phase II clinical program evaluating the effect of repeated cycles of the company's investigative immune-modulator, recombinant human Interleukin-7 (CYT107), in the treatment of chronically HIV-1 infected patients classified as Immunological Non-Responders (INR) after at least 24 months of highly active anti-retroviral therapy (HAART).

21 Sep 2010

Haskell completes St. John Broken Arrow Hospital

The Haskell Company announces it has completed construction on St. John Broken Arrow Hospital and its accompanying medical office building and medical campus in Broken Arrow, Okla., marking the largest design/build health care project in the company’s 45-year history.

21 Sep 2010

Orthovita publishes clinical data from IDE pilot studies

Orthovita, Inc., an orthobiologics and biosurgery company, is pleased to announce the publication of "Clinical Experience Using Cortoss for Treating Vertebral Compression Fractures with Vertebroplasty and Kyphoplasty" in the September 15, 2010 edition of Spine.

21 Sep 2010

Cook Medical expands Spectrum Turbo-Ject line of antibiotic impregnated PICCs for CRBSIs

Responding to increased demand for technology to help prevent potentially fatal catheter-related bloodstream infections (CRBSIs), Cook Medical has expanded its Spectrum Turbo-Ject line of antibiotic impregnated peripherally inserted central venous catheters (PICCs) to treat a wider range of patient needs. For the first time, the clinical benefits of minocycline and rifampin-impregnated PICCs, a critical component in eliminating 250,000 potentially fatal CRBSIs in the U.S. annually, are now available in 3 French single and 6 French triple lumen sizes.

21 Sep 2010

Public health at risk as Vitamin D evidence mounts

A group of prevention-focused healthcare organizations has expressed deep concern over recently-proposed restrictions to OHIP coverage of Vitamin D testing in the province. The proposed new legislation will delist OHIP insured Vitamin D testing for most Ontarians. Exceptions will be made for those with osteoporosis, malabsorption syndromes, and individuals taking medications that interfere with vitamin D absorption or metabolism.

21 Sep 2010

NQF endorses 8 outcome measures for pulmonary, cardiovascular conditions and care provided in ICU

To improve healthcare quality and give patients and providers more information about the results of care, the National Quality Forum (NQF) has endorsed eight outcome measures for pulmonary and cardiovascular conditions and care provided in the intensive care unit (ICU). This is the first in a set of patient outcome measures NQF is reviewing.

20 Sep 2010

Genzyme announces Japanese approval of Synvisc viscosupplement for OA knee pain relief

Genzyme Corporation announced today that Japan's Ministry of Health, Labour and Welfare has approved Synvisc® (hylan G-F 20; 3 x 2 mL), indicated for the treatment of osteoarthritis of the knee. Reimbursement has been obtained and publicized by Japan's Central Social Insurance Medical Council.

20 Sep 2010

Micromet initiates MT103 phase 2 trial in adult ALL patients

Micromet, Inc. today announced the initiation of a phase 2 trial of the Company's lead product candidate blinatumomab (MT103) in adult patients with relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL). Blinatumomab is the first of a new class of agents called BiTE antibodies, designed to harness the body's T cells to kill cancer cells.

20 Sep 2010

MultiStem multipotent adult progenitor cell therapy preserves 'blood brain barrier'

Athersys, Inc. announced today the publication of a key study in the October issue of Experimental Neurology conducted by researchers at Athersys, the University of Texas Medical School, the Michael E. DeBakey Institute for Comparative Cardiovascular Science and Biomedical Devices, and Texas A&M University.

20 Sep 2010

FDA decides to review information on Avastin for advanced HER2-negative breast cancer

Genentech, Inc., a member of the Roche Group, today announced that information submitted by the company to the U.S. Food and Drug Administration (FDA) during the review of the supplemental Biologics License Applications (sBLAs) for Avastin (bevacizumab) for previously untreated (first-line) advanced HER2-negative breast cancer has been deemed a major amendment.

18 Sep 2010

$Study on role of SurgiCase Orthopaedics in correction of compound wrist fractures$

Study on role of SurgiCase Orthopaedics in correction of compound wrist fractures

Materialise announced that it would lend its considerable expertise in virtual surgical planning to researcher Dr. J. B. Jupiter, Chief Hand and Upper Extremity Service at Massachusetts General Hospital. Through an AO funded, IRB approved study, Dr. Jupiter will use SurgiCase(R) Orthopaedics to explore the advantages of computer-assisted surgery, virtual 3D planning and intra-operative use of patient-specific surgical guides in osteotomies to correct compound wrist fractures-the first research project of its kind.

17 Sep 2010

SBi reports continuing growth for S.T.A.R. ankle arthroplasty implant system

Small Bone Innovations, Inc. (SBi), a leading, privately held orthopedics company focused primarily on arthroplasty and trauma reconstruction technology and treatments for the small bones & joints, reported continuing growth for its S.T.A.R. ankle arthroplasty implant system with August being the biggest month ever for the S.T.A.R. in terms of revenues and surgeries.

From Evident Corporation - Life Sciences 17 Sep 2010

Study identifies venous thromboembolism risk factors after THR surgery

Risk factors for venous thromboembolism after total hip replacement (THR) surgery were identified in a new study published in the September 2010 issue of The Journal of Bone and Joint Surgery (JBJS). While the rate of thromboembolism has been significantly reduced through medication, understanding the risk factors could further reduce the likelihood of patients developing this potentially fatal complication.

17 Sep 2010

Fat-derived stem cells can aid breast reconstruction after mastectomy

Fat-derived stem cells can be safely used to aid reconstruction of breast tissue after mastectomy as long as there is no evidence of active cancer, according to researchers at the University of Pittsburgh School of Medicine.

17 Sep 2010

FEMR and State of Illinois proclaim first-ever Fall Prevention Awareness Day

The Foundation for Education and Musculoskeletal Research (FEMR) and the state of Illinois officially proclaimed the first day of autumn, September 22, 2010, as Fall Prevention Awareness Day. FEMR will be raising awareness for fall prevention and the need for osteoporosis screening and treatment in an effort to reduce the incidence of fragility bone fractures among older residents of Illinois.

17 Sep 2010

Research on BMP6 protein suggests potential therapeutic target for Alzheimer's disease

Elevated levels of a growth protein in the brains of Alzheimer's disease (AD) patients is linked to impaired neurogenesis, the process by which new neurons are generated, say researchers at the University of California, San Diego in today's edition of The Journal of Neuroscience.

17 Sep 2010

Scientists discover protein to regulate blood stem cells’ activity for leukemia treatment

A discovery made by Dr. Tarik Möröy, President and Scientific Director and Director of the IRCM, and his team was recently published in Blood, the official journal of the American Society of Hematology. The researchers found that a protein can regulate certain characteristics of blood stem cells, which could lead to a better treatment for leukemia patients.

17 Sep 2010

Incyte Corporation publishes clinical trial data of INCB18424 drug for myelofibrosis treatment

Incyte Corporation, Results from a Phase I/II study of Incyte's janus kinase (JAK) inhibitor with the investigational name INCB18424 (also known as INCB018424 and INC424) were published today in The New England Journal of Medicine, demonstrating marked and durable clinical benefits in patients with myelofibrosis.

16 Sep 2010

Bone News and Research

New genes associated with osteoarthritis progression

FDA grants orphan drug designation for MultiStem stem cell therapy

Cytheris commences enrollment in CYT107 recombinant human Interleukin-7 clinical trial for HIV

Haskell completes St. John Broken Arrow Hospital

Orthovita publishes clinical data from IDE pilot studies

Cook Medical expands Spectrum Turbo-Ject line of antibiotic impregnated PICCs for CRBSIs

Public health at risk as Vitamin D evidence mounts

NQF endorses 8 outcome measures for pulmonary, cardiovascular conditions and care provided in ICU

Genzyme announces Japanese approval of Synvisc viscosupplement for OA knee pain relief

Micromet initiates MT103 phase 2 trial in adult ALL patients

MultiStem multipotent adult progenitor cell therapy preserves 'blood brain barrier'

FDA decides to review information on Avastin for advanced HER2-negative breast cancer

Study on role of SurgiCase Orthopaedics in correction of compound wrist fractures

SBi reports continuing growth for S.T.A.R. ankle arthroplasty implant system

Study identifies venous thromboembolism risk factors after THR surgery

Fat-derived stem cells can aid breast reconstruction after mastectomy

FEMR and State of Illinois proclaim first-ever Fall Prevention Awareness Day

Research on BMP6 protein suggests potential therapeutic target for Alzheimer's disease

Scientists discover protein to regulate blood stem cells’ activity for leukemia treatment

Incyte Corporation publishes clinical trial data of INCB18424 drug for myelofibrosis treatment

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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