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NICE suggests bortezomib, thalidomide for multiple myeloma patients

The National Institute for Health and Clinical Excellence (NICE) has released draft guidance which recommends the drugs bortezomib and thalidomide as first-line therapies for some patients with multiple myeloma, a type of cancer that affects cells in the bone marrow.

27 Aug 2010

DePuy Orthopaedics announces voluntary recall of ASR XL Acetabular and Hip Resurfacing systems

DePuy Orthopaedics, Inc., announced it is voluntarily recalling the ASR™ XL Acetabular System and DePuy ASR™ Hip Resurfacing System used in hip replacement surgery due to the number of patients who required a second hip replacement procedure, called a revision surgery.

26 Aug 2010

Data from PLX4032 Phase 1 clinical trial in melanoma patients with BRAF mutation published

Plexxikon today announced publication of data from the Phase 1 clinical trial of PLX4032 (RG7204), confirming that treatment of metastatic melanoma patients with the BRAF V600E mutation resulted in significant tumor shrinkage in the majority of patients. Specifically, in the melanoma extension cohort of the study, nearly all patients showed some response; 81 percent of patients had tumor shrinkage of at least 30 percent.

26 Aug 2010

PLX4032 therapy results in tumor shrinkage in metastatic melanoma patients

A multicenter study has concluded that treatment with a new targeted therapy called PLX4032 (also called RG7204) resulted in significant tumor shrinkage in 80 percent of patients with advanced melanoma.

26 Aug 2010

Phase 1 CRLX101 clinical study paves way for promising innovations in cancer therapy: Cerulean Pharma

Cerulean Pharma Inc., a leader in designing and developing nanopharmaceuticals, today announced that results of a Phase 1 clinical study of CRLX101 (formerly IT-101), Cerulean's lead clinical development candidate, and pre-clinical data on Cerulean's development candidate, CRLX288, were presented at the American Chemical Society National Meeting & Exposition, ongoing in Boston, Massachusetts.

26 Aug 2010

FDA grants LFB's recombinant anti-CD20 monoclonal antibody orphan drug status for CLL

The recombinant anti-CD20 monoclonal antibody produced by LFB Biotechnologies received orphan drug status for the treatment of Chronic Lymphocytic Leukemia (CLL). This approval from the FDA Office of Orphan Products Development was granted on August 6th, 2010.

26 Aug 2010

TRT receives patent rights for procedure of reattaching damaged soft tissue to bone

Tissue Regeneration Technologies, LLC (TRT), a Woodstock, Georgia medical technology company, recently received the rights to a new patent to bolster its SoftWave technology portfolio. The patent covers a method of reattaching damaged soft tissue to bone.

26 Aug 2010

3D MRI enhances visualization, displays fetal anatomy and diagnosing problems

Three-dimensional MRI is an emerging and useful technique for displaying fetal anatomy and diagnosing problems in the womb in a wide spectrum of clinical applications, according to Jeffrey C. Hellinger, M.D., a pediatric imaging specialist at Stony Brook University Medical Center.

26 Aug 2010

NeoStem responds to court ruling blocking government funding for embryonic stem cell research

NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, commented today on the ruling this week of a U.S. District Court blocking the federal government from funding research involving human embryonic stem cells. In issuing a preliminary injunction, the judge said it violated a law first passed in 1996 prohibiting federal money for research where a human embryo is destroyed.

25 Aug 2010

NIH awards University of Rochester Medical Center $15M grant for study with ImmuneRegen's Homspera

ImmuneRegen BioSciences®, a wholly owned subsidiary of IR Biosciences Holdings Inc., today announced that the National Institute of Health/National Institute of Allergy and Infectious Disease, has awarded its research partner, the University of Rochester Medical Center (URMC), a $15 million five-year, continuation grant for studies that will utilize ImmuneRegen's Homspera.

25 Aug 2010

Sea food for babies

Has your toddler eaten fish today? A University of Illinois food science professor has two important reasons for including seafood in your young child's diet, reasons that have motivated her work in helping to develop a tasty, nutritious salmon baby food for toddlers.

25 Aug 2010

Celgene to enforce REVLIMID intellectual property rights following receipt of Paragraph IV notification letter

Celgene Corporation today announced that information was posted on the FDA Web site indicating that an Abbreviated New Drug Application (ANDA) has been received by the Office of Generic Drugs (OGD) containing a "Paragraph IV" patent certification, for REVLIMID (lenalidomide) 25 mg capsules. Celgene has not yet received the Paragraph IV notification letter identifying the filer.

25 Aug 2010

Holy Cross Hospital performs first advanced sensor assisted knee surgery

The first advanced sensor assisted knee surgery in the world has been performed at Holy Cross Hospital in Fort Lauderdale, Fla. Through collaboration with OrthoSensor, Inc. in Fort Lauderdale, the new sensor technology is designed to improve patient recovery and overall implant function.

25 Aug 2010

Jordan Hospital receives approval to open new Wound Healing and Hyperbaric Center

Jordan Hospital is pleased to announce that it has received approval from the Massachusetts Department of Public Health for the opening of its new, state-of-the-art Wound Healing and Hyperbaric Center located on the hospital campus in Plymouth, Mass. The Wound Center features the only hospital-based hyperbaric treatment chamber in the greater Plymouth and Cape Cod region. The new Wound Center provides individuals with chronic, non-healing wounds, a local option for wound care and hyperbaric therapy.

25 Aug 2010

Also in Global Health News: IDUs in Kenya; Haiti recovery; Pandemic preparedness; Somalia hunger; HIV in Mozambique; Strengthening immune system against HIV

In Kenya, "[i]ntravenous drug users (IDUs) have been largely ignored by the government's HIV programmes on the basis that drug-taking is illegal, but a new policy is being drafted with the aim of reducing HIV transmission among this high-risk group," IRIN/PlusNews reports. The article includes comments from Nicholas Muraguri, head of the National AIDS and Sexually Transmitted Infections Control Programme, who said that the policy would treat drug use as a health issue, not a criminal one.

25 Aug 2010

Scientists discover influence of vitamin D in genes linked with autoimmune diseases

UK scientists at the University of Oxford have discovered that vitamin D can affect the activity of more than 200 genes of cells grown in the lab. Some of these genes are known from previous studies to be involved in diseases like diabetes and cancer.

24 Aug 2010

Polyphenols affect nutrient absorption: Study

Health benefits from polyphenol antioxidants - substances found in many fruits and vegetables - may come at a cost to some people. Penn State nutritional scientists found that eating certain polyphenols decreased the amount of iron the body absorbs, which can increase the risk of developing an iron deficiency.

24 Aug 2010

Asia's first 'custom fit knee replacement surgery' performed at Fortis Hospitals

Combining the latest technology, medical breakthroughs and personalized patient care, Fortis Hospitals Bangalore today announced Asia's first 'Custom Fit Knee Replacement Surgery' performed on a series of patients. Dr. Sanjay Pai, Chief Orthopedic Surgeon, along with his team performed this revolutionary surgery for the first time in the Asian Continent by precisely matching the size and placement of the implant specific to the patients' knee size. This procedure ensures lesser pain, less tissue damage, faster mobilization and longer lasting implant solution.

24 Aug 2010

Genzyme announces publication of phase 2 clinical trial results of eliglustat tartrate for Gaucher disease

Genzyme Corporation announced today that the two-year follow-up results from the phase 2 clinical trial of its investigational therapy known as eliglustat tartrate have been accepted for publication in the journal Blood. The results have been pre-published on the journal's website and are available to subscribers.

23 Aug 2010

Study finds occurrence of low BMD in inflammatory bowel disease patients

A thesis from the University of Gothenburg (Sweden) is the first in Scandinavia to study the occurrence of low bone mineral density in children and teenagers with inflammatory bowel disease. Half of the patients in the study showed signs of low bone mineral density.

23 Aug 2010

Bone News and Research

NICE suggests bortezomib, thalidomide for multiple myeloma patients

DePuy Orthopaedics announces voluntary recall of ASR XL Acetabular and Hip Resurfacing systems

Data from PLX4032 Phase 1 clinical trial in melanoma patients with BRAF mutation published

PLX4032 therapy results in tumor shrinkage in metastatic melanoma patients

Phase 1 CRLX101 clinical study paves way for promising innovations in cancer therapy: Cerulean Pharma

FDA grants LFB's recombinant anti-CD20 monoclonal antibody orphan drug status for CLL

TRT receives patent rights for procedure of reattaching damaged soft tissue to bone

3D MRI enhances visualization, displays fetal anatomy and diagnosing problems

NeoStem responds to court ruling blocking government funding for embryonic stem cell research

NIH awards University of Rochester Medical Center $15M grant for study with ImmuneRegen's Homspera

Sea food for babies

Celgene to enforce REVLIMID intellectual property rights following receipt of Paragraph IV notification letter

Holy Cross Hospital performs first advanced sensor assisted knee surgery

Jordan Hospital receives approval to open new Wound Healing and Hyperbaric Center

Also in Global Health News: IDUs in Kenya; Haiti recovery; Pandemic preparedness; Somalia hunger; HIV in Mozambique; Strengthening immune system against HIV

Scientists discover influence of vitamin D in genes linked with autoimmune diseases

Polyphenols affect nutrient absorption: Study

Asia's first 'custom fit knee replacement surgery' performed at Fortis Hospitals

Genzyme announces publication of phase 2 clinical trial results of eliglustat tartrate for Gaucher disease

Study finds occurrence of low BMD in inflammatory bowel disease patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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