Bone Marrow News and Research

RSS

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Research sheds light on post-sepsis immune suppression mechanism

Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more susceptible to recurrent infections.

13 Apr 2024

Heart transplant recipient's journey: From patient to advocate

Glen Kelley's journey as a heart transplant recipient came full circle today in Prague, as he addressed attendees of the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), including members of his own care teams.

12 Apr 2024

Innovative cancer treatment approach yields promising results in pediatric patients

Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumor samples.

12 Apr 2024

Study shows GHRH antagonist's role in AML drug resistance

A new research paper was published in Oncotarget's Volume 15 on April 8, 2024, entitled, "Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia."

10 Apr 2024

New lab assay could make diagnosis and treatment of lung cancer easier

A new lab assay developed by researchers at Fred Hutch Cancer Center could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier.

10 Apr 2024

Periostin may be a novel therapeutic target for treating esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) accounts for around 90% of esophageal cancers, especially in East Asia.

9 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

New immunotherapy strategy potentially lays the groundwork for treating autoimmune diseases

Mayo Clinic scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases.

1 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024

Familial Alzheimer's transmissible through bone marrow transplants, study shows

Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show March 28 in the journal Stem Cell Reports.

28 Mar 2024

New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Groundbreaking atlas maps over 80 blood stem cell types

Thanks to an unusual application of game theory and machine learning technology, a large team of scientists led by experts at Cincinnati Children's has published the world's most detailed "atlas" of the many types of stem cells and early progenitors involved in producing human blood from diverse donors.

21 Mar 2024

Needle pain is a big problem for kids. One California doctor has a plan.

Almost all new parents go through it: the distress of hearing their child scream at the doctor's office.

20 Mar 2024

Study reveals why COVID-19 antibodies fade quickly

Researchers at the Institute of Human Virology (IHV) at the University of Maryland School of Medicine published a new study in the Journal of Infectious Diseases investigating the antibody response following SARS-CoV-2 infection.

18 Mar 2024

Researchers pioneer a novel approach to enhance diabetic wound healing

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

14 Mar 2024

Blood test shows 83% accuracy in detecting colorectal cancer

A blood test intended for screening for colorectal cancer in people who are of average risk and not experiencing symptoms correctly detected colorectal cancer in 83% of people confirmed to have the disease, according to a study published March 14 in the New England Journal of Medicine.

13 Mar 2024

Novel tool to predict a person's risk for cardiovascular complications after bone marrow transplant

For thousands of Americans each year, a bone marrow transplant has the potential to cure diseases such as leukemias, lymphomas and immune deficiency disorders.

13 Mar 2024

Breakthrough CRISPR technique unlocks insights about cancer immunology

Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer.

29 Feb 2024

UMass Amherst study targets aplastic anemia with cell retraining approach

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

27 Feb 2024

Innovative therapy targets and destroys leukemia stem cells

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells.

26 Feb 2024