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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.
Cleveland Clinic researcher awarded grant to advance treatment of lethal prostate cancer

Cleveland Clinic researcher awarded grant to advance treatment of lethal prostate cancer

The Prostate Cancer Foundation has presented Nima Sharifi, M.D., Kendrick Family Endowed Chair for Prostate Cancer Research at Cleveland Clinic's Lerner Research Institute, a Challenge Award to advance the treatment of lethal prostate cancer. He is also co-investigator on a second Challenge Award that was also selected for funding. [More]
Researchers find CREB-activated genes in long-term memory-trained worms

Researchers find CREB-activated genes in long-term memory-trained worms

A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging. [More]
Researchers uncover mechanism by which anti-inflammatory processes may cause Alzheimer's

Researchers uncover mechanism by which anti-inflammatory processes may cause Alzheimer's

Inflammation has long been studied in Alzheimer's, but in a counterintuitive finding reported in a new paper, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease. [More]
Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management

Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management

Alexza Pharmaceuticals, Inc. announced today that it has initiated a Phase 2a study of AZ-002 (Staccato alprazolam), which is being developed for the management of epilepsy in patients with acute repetitive seizures (ARS). [More]
USC neuroscientists find potential prevention for Alzheimer's disease

USC neuroscientists find potential prevention for Alzheimer's disease

University of Southern California neuroscientists may have unlocked another puzzle to preventing risks that can lead to Alzheimer's disease. Researchers at Keck Medicine of USC used high-resolution imaging of the living human brain to show for the first time that the brain's protective blood barrier becomes leaky with age, starting at the hippocampus, a critical learning and memory center that is damaged by Alzheimer's disease. [More]
Taking hormonal contraceptives for five years doubles brain tumour risk

Taking hormonal contraceptives for five years doubles brain tumour risk

Taking a hormonal contraceptive for at least five years is associated with a possible increase in a young woman's risk of developing a rare tumour, glioma of the brain. This project focussed on women aged 15 -49 years and the findings are published in the British Journal of Clinical Pharmacology. [More]
New article provides insight into cognitive fatigue in people with multiple sclerosis

New article provides insight into cognitive fatigue in people with multiple sclerosis

Kessler Foundation researchers have authored a new article that provides insight into the factors that contribute to cognitive fatigue in individuals with multiple sclerosis (MS). The article, "Subjective cognitive fatigue in MS depends on task length," was epublished ahead of print on October 27 in Frontiers in Neurology. [More]

People may have to 'turn on' their memories to remember experiences

People may have to "turn on" their memories in order to remember even the simplest details of an experience, according to Penn State psychologists. This finding, which has been named "attribute amnesia," indicates that memory is far more selective than previously thought. [More]
Elekta updates latest R&D work with special focus on high field MRI-guided radiation therapy

Elekta updates latest R&D work with special focus on high field MRI-guided radiation therapy

Elekta updated the market this morning on its latest research and development initiatives, with special focus on Atlantic, the first generation high field MRI-guided radiation therapy system. The company unveiled plans to introduce this game-changing technology in 2017 and deliver the first systems in 2018. [More]
Study: Prostate cancer drug stabilizes memory loss for a year in women with Alzheimer's disease

Study: Prostate cancer drug stabilizes memory loss for a year in women with Alzheimer's disease

Women with Alzheimer's disease showed stable cognition for a year when a drug that is more commonly used to treat advanced prostate cancer was added to their drug regimen, according to a new study from researchers at the University of Wisconsin-Madison. [More]
ENIGMA scientists discover eight genetic mutations that may erode or boost brain tissue

ENIGMA scientists discover eight genetic mutations that may erode or boost brain tissue

In the largest collaborative study of the brain to date, researchers from the Keck School of Medicine of the University of Southern California led a global consortium of 190 institutions to identify eight common genetic mutations that appear to age the brain an average of three years. The discovery could lead to targeted therapies and interventions for Alzheimer's disease, autism and other neurological conditions. [More]
Two new drug compounds appear to be effective in treating endometriosis

Two new drug compounds appear to be effective in treating endometriosis

Two new drug compounds - one of which has already proven useful in a mouse model of multiple sclerosis - appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine. [More]
Personalized approaches to treating intellectual disability

Personalized approaches to treating intellectual disability

Scientists from the Florida campus of The Scripps Research Institute have produced an approach that protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels. [More]
Researchers identify promising new target for developing better therapies for neuroblastoma kids

Researchers identify promising new target for developing better therapies for neuroblastoma kids

Researchers at the University of Michigan's C.S. Mott Children's Hospital have identified a promising new target for developing new therapies for kids with high-risk neuroblastoma, according to a new study published in Molecular Cancer Research. [More]
Study offers possible explanation for differences between synchronization patterns in autism

Study offers possible explanation for differences between synchronization patterns in autism

Autism spectrum disorder (ASD) has been studied for many years, but there are still more questions than answers. For example, some research into the brain functions of individuals on the autism spectrum have found a lack of synchronization between different parts of the brain that normally work in tandem. But other studies have found the exact opposite - over-synchronization in the brains of those with ASD. [More]
Daily use of Pycnogenol may help improve overall cognitive function

Daily use of Pycnogenol may help improve overall cognitive function

New research delivers exciting news for those seeking natural ways to boost memory and mental performance. A study recently published in the Journal of Neurosurgical Sciences shows daily use of Pycnogenol (pic-noj-en-all), a natural plant extract from French maritime pine tree bark, may help improve attention span, memory, decision-making – including executive-level performance – and overall cognitive function. [More]
Walnuts may improve cognitive function

Walnuts may improve cognitive function

Eating walnuts may improve performance on cognitive function tests, including those for memory, concentration and information processing speed according to new research from the David Geffen School of Medicine at The University of California, Los Angeles, led by Dr. Lenore Arab. Cognitive function was consistently greater in adult participants that consumed walnuts, regardless of age, gender or ethnicity. [More]
Penn researchers make breakthrough on novel anesthetics

Penn researchers make breakthrough on novel anesthetics

Penn Medicine researchers, in a continuation of their groundbreaking work to better understand how anesthesia works in the body, have found the first new class of novel anesthetics since the 1970s. Their findings, published in February issue of Anesthesiology, detail the processes through which the group uncovered these compounds. [More]
Pfizer, Avon Foundation for Women reveal Avon-Pfizer Metastatic Breast Cancer Grants Program recipients

Pfizer, Avon Foundation for Women reveal Avon-Pfizer Metastatic Breast Cancer Grants Program recipients

Today, Pfizer Inc. and the Avon Foundation for Women are proud to announce the first-ever recipients of the Avon-Pfizer Metastatic Breast Cancer Grants Program: Identify-Amplify-Unify. [More]
Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant. [More]