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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

CMS121 holds promise for treating metabolic diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction."

9 Apr 2024

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.

9 Apr 2024

Network analysis reveals subtle changes associated with subjective cognitive decline

We all lose our car keys or our glasses from time to time. Most people would be correct to laugh it off as a normal part of aging.

9 Apr 2024

Researchers elucidate how gene mutation mechanism causes autism

Researchers show how mutations of gene transcription and chromatin regulation-related genes cause autism.

9 Apr 2024

Electroconvulsive Therapy found to be safe and effective treatment for some mental illnesses

Researchers have found that Electroconvulsive Therapy (ECT), where an electric current is passed through the brain, can reduce the severity of mental illnesses.

9 Apr 2024

Step steady: Consistent walking improves brain function in older adults

Study highlights that stabilizing daily step variability, rather than increasing total step counts, improves cognitive flexibility in older adults following a 10-week physical activity intervention.

8 Apr 2024

Gut microbiome shows no clear link to cognitive impairments in Parkinson's disease

Study investigates the gut microbiome's role in Parkinson's disease patients with mild cognitive impairments, revealing no distinct microbiome signatures associated with MCI in PD compared to cognitively normal PD patients or controls.

8 Apr 2024

Chronic low-level inflammation may be a contributor to both depression and heart disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers at Vanderbilt University Medical Center and Massachusetts General Hospital have found.

8 Apr 2024

Study uncovers how consensual touch can benefit a person's physical and mental wellbeing

Through a large-scale analysis, researchers at the Netherlands Institute for Neuroscience have uncovered the ways in which consensual touch can benefit a person's physical and mental wellbeing.

8 Apr 2024

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically rather than intravenously did not meet its primary endpoint of reducing seizures and was stopped early due to an increased risk of bleeding events, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Prenatal cannabis use disorder linked to increased risk of neurodevelopmental disorders in offspring

A new study presented at the European Psychiatric Association Congress 2024 reveals a significant association between prenatal cannabis use disorder (CUD) and an increased risk of neurodevelopmental disorders in offspring, including attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and intellectual disability (ID).

8 Apr 2024

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

Alzheimer's disease and Parkinson's disease, along with stroke, are among the top three neurodegenerative disorders, characterized by the malfunction and progressive degeneration of neurons, the nerve cells.

8 Apr 2024

Impella CP pump shows survival benefit in cardiogenic shock

Implantation of the Impella CP micro-axial flow pump in the hours after a heart attack significantly increased the rate of survival at six months among people suffering cardiogenic shock, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Expanding research and clinical options for children with cancer

In this interview, Dr. Church, the Molecular and Pediatric Pathologist at Boston Children's Hospital, talks to NewsMedical about their work in pediatric oncology, and the need to expand research and clinical options for children with cancer.

From Tecan 8 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Genetic link between PTSD and Alzheimer's debunked in veterans study

Study reveals that the genetic risk factor for Alzheimer’s disease, APOE ε4, does not increase PTSD risk among combat veterans, challenging the previously suggested link between PTSD and future dementia.

7 Apr 2024

Neural implants face ethical hurdles, study finds

Study delves into the ethical, design, and clinical trial challenges of AI-driven neural implants, highlighting the need for advancements in accuracy, user privacy, and societal acceptance.

7 Apr 2024

Obesity and high-fat diets linked to accelerated aging in brain blood vessels

A new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood to the brain.

7 Apr 2024

Blast exposure can cause intestinal permeability, study shows

A study by New York and Rocky Mountain U.S. Department of Veterans Affairs researchers showed blast exposure can cause intestinal permeability, a condition that can lead to gut bacteria entering the bloodstream and causing problems in other parts of the body.

5 Apr 2024

Mitochondrial fusion critical for adult neurogenesis and brain circuit refinement

Nerve cells (neurons) are amongst the most complex cell types in our body. They achieve this complexity during development by extending ramified branches called dendrites and axons and establishing thousands of synapses to form intricate networks.

5 Apr 2024

Brain News and Research

Further Reading

CMS121 holds promise for treating metabolic diseases

Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Network analysis reveals subtle changes associated with subjective cognitive decline

Researchers elucidate how gene mutation mechanism causes autism

Electroconvulsive Therapy found to be safe and effective treatment for some mental illnesses

Step steady: Consistent walking improves brain function in older adults

Gut microbiome shows no clear link to cognitive impairments in Parkinson's disease

Chronic low-level inflammation may be a contributor to both depression and heart disease

Study uncovers how consensual touch can benefit a person's physical and mental wellbeing

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Prenatal cannabis use disorder linked to increased risk of neurodevelopmental disorders in offspring

NeuM technology revolutionizes neuron labeling for neurodegenerative disease research

Impella CP pump shows survival benefit in cardiogenic shock

Expanding research and clinical options for children with cancer

Gut-friendly psychobiotics could brighten moods and fight depression

Genetic link between PTSD and Alzheimer's debunked in veterans study

Neural implants face ethical hurdles, study finds

Obesity and high-fat diets linked to accelerated aging in brain blood vessels

Blast exposure can cause intestinal permeability, study shows

Mitochondrial fusion critical for adult neurogenesis and brain circuit refinement

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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