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There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Also called glioma, meningioma.
Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report. [More]
Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN. [More]
Researchers design smart drug to treat patients with most aggressive brain cancers

Researchers design smart drug to treat patients with most aggressive brain cancers

Physicians and researchers at Houston Methodist Hospital have designed a new drug to treat patients with the most aggressive, incurable brain cancers. [More]
Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. [More]
Experimental cancer imaging tool shows promise in illuminating brain tumors during surgery

Experimental cancer imaging tool shows promise in illuminating brain tumors during surgery

An experimental cancer imaging tool that makes tumors glow brightly during surgery has shown promise again in a new Penn Medicine clinical study, this time in patients with brain cancer. [More]
Cancer researchers identify important driver of tumor cell invasion in glioblastoma

Cancer researchers identify important driver of tumor cell invasion in glioblastoma

University of Hawai'i Cancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at any age. [More]
Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches

Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches

Astronauts survive in space by wearing high-tech space suits. But how do brain cancer cells thrive when they migrate to inhospitable sites within the brain? [More]
Scientists identify genetic mutations in highly aggressive rhabdoid meningiomas

Scientists identify genetic mutations in highly aggressive rhabdoid meningiomas

Meningiomas are the most common primary brain tumors, but the term encompasses over a dozen subtypes that range from benign to highly aggressive. [More]
DNAtrix enters into license agreement with University of Florida to develop new oncolytic virus platform

DNAtrix enters into license agreement with University of Florida to develop new oncolytic virus platform

DNAtrix, a clinical stage biotechnology company developing virus-driven immunotherapies for cancer, announced it has entered into an exclusive license agreement with the University of Florida, Gainesville to develop a novel oncolytic virus platform. [More]
Researchers identify potential new treatment for brain cancer by targeting genes linked to microcephaly

Researchers identify potential new treatment for brain cancer by targeting genes linked to microcephaly

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential new treatment for brain cancer by learning from a rare condition that can cause microcephaly. [More]
Researchers identify existing drugs that appear to prevent aggressive subtype of pediatric brain tumors

Researchers identify existing drugs that appear to prevent aggressive subtype of pediatric brain tumors

More than 4,000 children and teens are diagnosed with brain cancer each year and the disease kills more children than any other cancer. [More]
Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries. [More]
Scientists modify structure of cancer drug to enhance ability to pass through blood-brain barrier

Scientists modify structure of cancer drug to enhance ability to pass through blood-brain barrier

In efforts to develop new treatments for brain cancer, scientists from Johns Hopkins Drug Discovery and the Kimmel Cancer Center's Bloomberg~Kimmel Institute for Cancer Immunotherapy report they have altered the structure of an experimental drug that seems to enhance its ability to slip through the mostly impermeable blood-brain barrier. [More]
How could emerging technologies impact cancer care?

How could emerging technologies impact cancer care?

The major innovations in cancer diagnosis, therapy/palliative care and surgical intervention are too numerous to list here. But enormous strides have taken place in stem cell therapy, monoclonal antibody therapy and genetic screening. [More]
Researchers develop MRI-based method that can track progression of genetically mutated gliomas

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

UT Southwestern Medical Center researchers have developed an MRI-based method that can track the state and progression of a common type of genetically mutated brain cancer. [More]
Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models

Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models

Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in mouse models. [More]
Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer

A high response rate with a single drug in a phase I/II trial of paediatric brain tumour has set the stage for combination therapy with higher response and lower toxicity, researchers reported at the ESMO 2016 Congress in Copenhagen. [More]
Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease

Immunotherapy already in clinical trials for cancer could slow progression of Parkinson's disease

Researchers at Johns Hopkins report they have identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal's brain — and a way to block that protein's action. [More]
HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows

HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows

Every 20 minutes, someone in the United States receives a cancer diagnosis related to human papillomavirus. HPV causes cancer of the cervix, anus and throat. [More]
UC football team supports brain cancer survivor

UC football team supports brain cancer survivor

In 2009, Mitch Stone was 11 when he was diagnosed with a brain tumor. He went through very aggressive treatments at Cincinnati Children's. [More]
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