Burkitt Lymphoma News and Research

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Burkitt Lymphoma is an aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that occurs most often in children and young adults. The disease may affect the jaw, central nervous system, bowel, kidneys, ovaries, or other organs. There are three main types of Burkitt lymphoma (sporadic, endemic, and immunodeficiency related). Sporadic Burkitt lymphoma occurs throughout the world, and endemic Burkitt lymphoma occurs in Africa. Immunodeficiency-related Burkitt lymphoma is most often seen in AIDS patients.

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

1 Feb 2024

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

16 Nov 2023

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting—to be held June 2-6 in Chicago, Illinois—Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances in treatments and clinical trials, how access to cancer care affects outcomes, integrative medicine and more.

5 Jun 2023

Modified R-CODOX-M/IVAC regimen shows promise for treating sporadic Burkitt lymphoma

Burkitt lymphoma (BL) is a highly aggressive form of non-Hodgkin lymphoma (NHL) that comes in three different variants: endemic, immunodeficiency-associated, and sporadic. Of these variants, sporadic BL is most commonly found outside malaria-endemic countries and typically seen in young adults.

1 Sep 2021

Efficacy of polymeric nano-micelles depends on expression level of c-Myc

The Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki in Japan, Abbreviation: iCONM) reported in ACS Nano (Impact Factor: 14.588 in 2019) together with the group of Prof. Yu Matsumoto of Otorhinolaryngology and Head and Neck Surgery (Prof. Tatsuya Yamasoba) and the group of Prof. Horacio Cabral of the Department of Bioengineering (Prof. Ryo Miyake) in the University of Tokyo that the efficacy of polymeric nano-micelles with different drug activation profile depends on the expression level of c-Myc, one of the major proto-oncogene, has been developed.

27 Feb 2021

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy.

16 Sep 2020

Kids with silent malaria remain vulnerable to developing endemic Burkitt lymphoma

A study has found strong similarities between children with endemic Burkitt lymphoma — an aggressive cancer that attacks the body's defense system and children with silent malaria infection.

10 Aug 2020

Phase III clinical trial shows benefit of rituximab for pediatric Burkitt lymphoma

Results of the phase III Inter-B-NHL-ritux 2010 clinical trial reported today in the New England Journal of Medicine show 95 percent three-year survival for pediatric patients with advanced B-cell non-Hodgkin lymphoma treated with the addition of anti-cancer immunotherapy rituximab to standard chemotherapy.

3 Jun 2020

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

More than 60 years ago, British physician Denis Parsons Burkitt and his associates achieved one of the signal successes in cancer medicine when they cured children in sub-Saharan Africa with a form of lymphoma by treating them with high doses of the chemotherapy drug cyclophosphamide.

2 Jul 2019

Johns Hopkins researchers uncover role of neurotransmitter in the spread of aggressive cancers

Using human cancer cells, tumor and blood samples from cancer patients, researchers at Johns Hopkins Medicine have uncovered the role of a neurotransmitter in the spread of aggressive cancers. Neurotransmitters are chemical "messengers" that transmit impulses from neurons to other target cells.

25 Apr 2019

New approach may improve translation of immunological research findings

Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses.

27 Jul 2017

Scientists identify potential therapeutic target for aggressive lymphomas

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified a possible therapeutic target for 2 types of very aggressive lymphomas.

28 Feb 2017

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

A study by scientists at the University of Glasgow, which reveals the critical role a common cancer-associated gene plays in lymphoma development, could lead to improved treatments for a range of cancers.

11 May 2016

Researchers help explain how malaria infection increases children's risk of developing Burkitt's lymphoma

In equatorial Africa, a region of the globe known as the "lymphoma belt," children are ten times more likely than in other parts of the world to develop Burkitt's lymphoma, a highly aggressive blood cancer that can be fatal if left untreated. That area is also plagued by high rates of malaria, and scientists have spent the last 50 years trying to understand how the two diseases are connected.

14 Aug 2015

Burkitt Lymphoma News and Research

Study sheds light on 7-DHC's potential to induce cell death-resistant state in tumors

Gene splicing determines CD20 levels and response to monoclonal antibody therapy

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

Modified R-CODOX-M/IVAC regimen shows promise for treating sporadic Burkitt lymphoma

Efficacy of polymeric nano-micelles depends on expression level of c-Myc

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

A new therapeutic approach for Epstein-Barr virus-associated tumors

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Kids with silent malaria remain vulnerable to developing endemic Burkitt lymphoma

Phase III clinical trial shows benefit of rituximab for pediatric Burkitt lymphoma

Large doses of traditional chemotherapy drug spur immune system attack on cancer cells

Johns Hopkins researchers uncover role of neurotransmitter in the spread of aggressive cancers

New approach may improve translation of immunological research findings

Scientists identify potential therapeutic target for aggressive lymphomas

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

Researchers help explain how malaria infection increases children's risk of developing Burkitt's lymphoma

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Melbourne researchers develop new genome editing technology to kill blood cancer cells

Patients with AIDS-related lymphomas may face increased risk of CNSi

Patrys provides update on development programme for anti-cancer product, PAT-LM1

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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