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Research shows blocking DNA repair improves radiation therapy for glioblastomas

UT Southwestern Medical Center researchers have demonstrated in both cancer cell lines and in mice that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for highly fatal brain tumors called glioblastomas. [More]

Study: Cetuximab drug used in combination with chemotherapy to treat advanced colorectal cancer is not effective

Research from the University of Southampton has shown a drug, used in combination with chemotherapy to treat advanced colorectal cancer, is not effective in some settings, and indeed may result in more rapid cancer progression. [More]

MicroBiome Therapeutics to present clinical trial data of NM504 in type 2 diabetes, prediabetes at ICE/ENDO 2014

MicroBiome Therapeutics LLC, today announced that data from the company's clinical trial of microbiome modulator NM504 in development for type 2 diabetes and prediabetes has been accepted for a Poster Preview Presentation at ICE/ENDO 2014, the joint meeting of the International Society of Endocrinology and The Endocrine Society. [More]
Pradaxa receives FDA approval for treatment and reduction of risk of recurrence of DVT and PE

Pradaxa receives FDA approval for treatment and reduction of risk of recurrence of DVT and PE

Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Pradaxa® (dabigatran etexilate mesylate) for the treatment of deep venous thrombosis (DVT) and pulmonary embolism (PE) in patients who have been treated with a parenteral anticoagulant for five to 10 days, and to reduce the risk of recurrent DVT and PE in patients who have been previously treated. DVT and PE are collectively referred to as venous thromboembolism (VTE). [More]
Researchers identify potential treatment targets for incurable form of pediatric brain cancer

Researchers identify potential treatment targets for incurable form of pediatric brain cancer

Researchers from the University of Toronto's Department of Laboratory Medicine and Pathobiology (LMP) have defined potential treatment targets for a previously incurable form of pediatric brain cancer called Diffuse Intrinsic Pontine Glioma (DIPG). [More]

UPCI/MWRI researchers to present results of immune gene profile exploring endometriosis and cancer

Some women with endometriosis, a chronic inflammatory disease, are predisposed to ovarian cancer, and a genetic screening might someday help reveal which women are most at risk, according to a University of Pittsburgh Cancer Institute (UPCI) study, in partnership with Magee-Womens Research Institute (MWRI). [More]

More young workers decline employer health coverage

Despite the mandate that most Americans carry health insurance or pay a penalty, young workers employed by large companies signed up for job-based health plans at a lower rate than last year, according to a report by payroll services company Automatic Data Processing Inc. Meanwhile, Connecticut gets another insurer, and employers continue to shift health care costs to their workers. [More]
Blood sample could diagnose many types of solid cancers

Blood sample could diagnose many types of solid cancers

A blood sample could one day be enough to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient's body and responses to treatment. Previous versions of the approach, which relies on monitoring levels of tumor DNA circulating in the blood, have required cumbersome and time-consuming steps to customize it to each patient or have not been sufficiently sensitive. [More]

ER physicians discount early signs of strokes among women, minorities, younger people

Analyzing federal health care data, a team of researchers led by a Johns Hopkins specialist concluded that doctors overlook or discount the early signs of potentially disabling strokes in tens of thousands of American each year, a large number of them visitors to emergency rooms complaining of dizziness or headaches. [More]

ZirMed acquires TransEngen's payment processing and patient engagement solutions

ZirMed, a leading health information connectivity and management solutions company, today announced that it has acquired the payment processing, patient eligibility and patient estimation business solutions owned by TransEngen Inc., a company located in Shelton, CT. [More]
Roundup: Battles fought over Lyme disease, autism and abortion

Roundup: Battles fought over Lyme disease, autism and abortion

In Texas, abortion providers file suit to block a state rule that could shut down many of the state's remaining clinics, while lawmakers in Vermont and N.Y. seek to immunize doctors who prescribe long-term antibiotics for patients with lasting symptoms attributed to Lyme disease. [More]
Dartmouth aims to remove barriers for pancreatic cancer photodynamic therapy

Dartmouth aims to remove barriers for pancreatic cancer photodynamic therapy

Using CT scans with contrast enhancement, Dartmouth researchers measured treatment response to pancreatic cancer photodynamic therapy (PDT) according to a paper published in Physics in Medicine and Biology. [More]
Patients who stay longer in ICU have substantial physical impairments 2 years later

Patients who stay longer in ICU have substantial physical impairments 2 years later

Patients have substantial physical impairments even two years after being discharged from the hospital after a stay in an intensive care unit (ICU), new Johns Hopkins research suggests. [More]

Maryland scraps exchange software, will buy Connecticut's system

Now that the enrollment period has ended, the board that runs Maryland's troubled online insurance marketplace has opted to start over with a system that worked well in Connecticut. [More]

New clinic that focuses on diagnosis and treatment for vertigo launched in Mumbai

In a first, a city hospital has launched a clinic dedicated to vertigo. Dr Rajeev Boudhankar, vice-president, Kohinoor Hospital, said, "We observed that vertigo is a highly under-diagnosed ailment and patients run from post to pillar looking for effective treatment. [More]
New neuromonitoring method prevents malpositioning of pedicle screws during thoracic spine surgery

New neuromonitoring method prevents malpositioning of pedicle screws during thoracic spine surgery

Researchers from Syracuse, New York, report a new, highly accurate, neuromonitoring method that can be used during thoracic spine surgery to prevent malpositioning of pedicle screws such that they enter the spinal canal and possibly cause postoperative neurological impairment. [More]
RPCI receives FDA approval to enroll patients in phase II clinical trial using I-PDT approach

RPCI receives FDA approval to enroll patients in phase II clinical trial using I-PDT approach

Roswell Park Cancer Institute (RPCI) has received U.S. Food and Drug Administration (FDA) approval to enroll patients in a phase II clinical trial that will use a unique and highly precise method of delivering interstitial photodynamic therapy (I-PDT) to recurrent tumors of the head and neck. [More]

FORMA Therapeutics signs second strategic collaboration and option agreement with Celgene

FORMA Therapeutics, an innovative R&D organization in pursuit of ground-breaking medicines in oncology and other therapeutic areas, today announced a second strategic collaboration and option agreement with Celgene Corporation, a leader in addressing high unmet medical needs. [More]

Brainlab, Mobius Imaging announce CE Mark approval for Airo Mobile Intraoperative CT

Brainlab, a global leader in medical technology and Mobius Imaging, developer of advanced imaging technologies, announced today CE Mark approval for Airo Mobile Intraoperative CT. The CE Mark allows Brainlab to begin installation of the systems sold in the European Union. [More]

Bruker introduces multiscale high-resolution X-ray nanotomograph, Skyscan 2211

At Analytica 2014, Bruker today introduced the SkyScan TM 2211, a new high-resolution X-ray nano-CT (computed tomography) system with the widest available range of object sizes and spatial resolutions. [More]