Cachexia News and Research

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Cachexia is a condition which denotes the excessive loss of weight. It occurs because of the depletion of adipose tissue and muscle mass in people who are not trying to lose weight.

DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Efficient neuronal activity detection in brain imaging.

25 Apr 2024

The whey to go: Researchers unlock the potential of whey-derived proteins for cancer prevention

The current evidence regarding the significance of whey protein for cancer prevention and treatment.

4 Apr 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Unlocking vitamin B6's role in pancreatic cancer and immune system battle

Vitamin B6 is beneficial in many ways, notably for its role in maintaining a strong immune system. However, when pancreatic cancer develops, its cells also need vitamin B6 to replicate.

23 Feb 2024

How African sleeping sickness melts away body fat: New study sheds light on the role of lipolysis

Researchers find that the T. brucei parasite, responsible for African trypanosomiasis, triggers weight loss by disrupting fat cell lipolysis. The study shows that ATGL enzyme is key to this process, potentially offering a new angle for future research and treatment.

17 Oct 2023

Plant-based proteins boost muscle mass and cut fat in older adults

Plant-based proteins are just as effective as animal-based options in maintaining muscle mass and strength in older adults, a new meta-analysis finds. The study shows that plant proteins can even aid in reducing fat mass, offering a sustainable and healthful option for combating age-related muscle decline.

24 Sep 2023

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).

1 Aug 2023

KIAA0930 could be a novel therapeutic target for cancer cachexia

A new research paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, "The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells."

26 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Immunodiagnosis: Unleashing the potential of personalized immunotherapy

Researchers discuss the concept of immunodiagnosis and explores the potential of artificial intelligence in ID systems for precise tumor immunotherapy.

18 Jul 2023

10 postdoctoral fellows from Latin America receive Pew funding for biomedical research

The Pew Charitable Trusts today announced the 2023 class members of the Pew Latin American Fellows Program in the Biomedical Sciences.

13 Jun 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Ingestible capsule uses electricity to boost production of hunger-regulating hormone

Hormones released by the stomach, such as ghrelin, play a key role in stimulating appetite. These hormones are produced by endocrine cells that are part of the enteric nervous system, which controls hunger, nausea, and feelings of fullness.

26 Apr 2023

Exercising during adolescence can lower the risk of sarcopenia at older age

Muscle function typically improves during adolescence and deteriorates with age. Sarcopenia is one such type of muscle weakening, caused primarily by the natural aging process.

25 Apr 2023

UH researcher examines the causes of skeletal muscle atrophy

Skeletal muscle atrophy, or wasting, is a devastating and often irreversible syndrome during the aging process and for patients with advanced cancer.

11 Apr 2023

ACC to host annual Advancing the Cardiovascular Care of the Oncology Patient course

The American College of Cardiology will host the annual Advancing the Cardiovascular Care of the Oncology Patient course on April 14-16, 2023, in Washington, DC.

10 Apr 2023

What are the effects of kimchi on human health?

Researchers evaluated the effectiveness of kimchi consumption on overall human health.

4 Apr 2023

Brown adipose tissue may help improve survival in people with cancer

Brown fat is not linked to cancer-associated loss of body weight and muscle mass, a common condition known as cachexia, according to a new joint study from The Rockefeller University and Memorial Sloan Kettering Cancer Center in New York City.

23 Mar 2023

How does the gut microbiome affect muscle strength?

Researchers use fecal microbiome transplantation in mouse models to examine the role of gut microbiota in determining muscle strength.

14 Mar 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023