Cancer Biomarker News and Research

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Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Proteomic signatures in blood plasma and cervicovaginal fluid for endometrial cancer detection.

26 Mar 2024

Hand-held biosensor detects breast cancer biomarkers from saliva

Breast cancer is on the rise, but new tools for early detection could save lives.

13 Feb 2024

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

Subcutaneous injection of the immunotherapy nivolumab (brand name Opdivo) is noninferior to intravenous delivery and dramatically reduces treatment time in patients with renal cell carcinoma, as seen in the results of a large phase 3 clinical trial reported today at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, California.

29 Jan 2024

Highly sensitive blood test shows promise for early detection of common deadly cancers

Most cancers become deadly by keeping a low profile, causing no symptoms until they're too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses.

1 Nov 2023

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.

5 Oct 2023

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level

A group of researchers investigated single-molecule electrical detection of ribonucleic acid (RNA) cancer biomarkers.

3 Aug 2023

Cancer-fighting immune cells can fuel their ability to attack tumors

When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that.

8 May 2023

Clinically relevant biomarker strategies in drug development

In this interview, NewsMedical speaks with Dr. Justin Devine and Dr. Nicholas Woudberg about biomarkers, their importance for drug development as well as the potential they have when it comes to machine learning.

From Synexa Life Sciences BV 9 Jan 2023

Remnants of ancient viruses in the human genome are active in normal tissues

Remnants of ancient viruses in the human genome are active in healthy tissues as well as diseased ones, limiting their utility as disease biomarkers, according to a study by Aidan Burn at Tufts University in Boston, USA and colleagues, publishing October 18th in the open access journal PLOS Biology.

18 Oct 2022

Neuropilin 2 identified as a novel regulator of distal colonic smooth muscle motility

Colonic motility disorders, especially problems associated with constipation and diarrhea, are common in adults and children, greatly impacting quality of life.

11 Oct 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

USA–Japan Workshop participants present cutting-edge research on biomarkers for early detection of cancer

Successful treatment of cancer frequently depends on early detection. However, many cancers are detected late, often after metastasizing to other sites.

9 Jun 2022

Biologists discover gene deletion behind abnormality in blood cancer cells

The mystery is being unraveled of why the control centers, or nuclei, of certain blood cancer cells have a distinctly odd shape.

27 Mar 2022

Research findings may explain marked racial disparity in deaths from triple negative breast cancer

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study led by Johns Hopkins Kimmel Cancer Center researchers suggests.

15 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Researchers develop new method for rapidly detecting SARS-CoV-2 RNA

DTU-researchers develop a novel method for rapidly detecting SARS-CoV-2 RNA that may also be designed to detect other diseases.

27 Sep 2021

Biomarker shows potential to predict immunotherapy benefit for breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

27 Jul 2021

3D printing technique extends the possibilities of lateral flow tests

Researchers at KU Leuven (Belgium) have developed a 3D printing technique that extends the possibilities of lateral flow testing.

10 May 2021

Researchers use a photostabilizer to modulate fluorescence blinking in biochemical assays

Fluorescence spectroscopy is indispensable in biomedical diagnostics. One can think of turning on fluorescence as turning on a flashlight in a dark room.

13 Apr 2021