Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

With support from Amplicore, a University of Cincinnati spinoff biopharmaceutical company, researchers at UC have begun a Department of Defense-funded clinical trial that seeks a regenerative pharmaceutical solution for meniscal tears.

10 Jul 2023

Combination of techniques reveals molecular changes in osteoarthritis

Osteoarthritis is the most common degenerative joint disease, affecting 22% of adults over 40 globally. Although the condition has been extensively studied through a medical perspective, the molecular changes associated with osteoarthritis remain unclear.

5 Jul 2023

Spicing up rheumatic disease treatment: Study explores role of herbs and spices in improving patients' condition

Research explores the potential benefits of herbs and spices in rheumatic diseases, highlighting their bioactive compounds and medicinal properties. It provides an updated review of their mechanisms of action and summarizes human studies in Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia.

4 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin-;generally prepared from porcine intestinal mucosa in China-;was threatened by African swine fever in 2018.

15 Jun 2023

Researchers develop protein biomarker panels to predict developmental dysplasia of the hip

Researchers from the University of Missouri School of Medicine have developed panels of protein biomarkers present in teens and young adults that distinguish individuals with healthy hips from those with developmental dysplasia of the hip, also known as hip dysplasia, which often progresses to hip osteoarthritis if not recognized before early adulthood.

13 Jun 2023

Life-changing procedure using new aortic valve device clears way for patient in need of liver transplant and hip replacement

Janice Couch, 62, a retired pre-school teacher from Grand Rapids, Michigan, is finally physically ready to receive two procedures that stand to change her life, thanks to Henry Ford Health interventional cardiologists who paved the way by implanting a new aortic valve device for the first time in the health system's history.

6 Jun 2023

Injectable fatty acid copolymer ARA 3000 BETA shows therapeutic potential in treating osteoarthritis

Researchers examined the therapeutic potential of ARA 3,000 BETA for treating osteoarthritis.

16 May 2023

Primary arthroscopy provides positive long-term outcomes for young adults with borderline hip dysplasia

For young adults with borderline hip dysplasia (BHD), primary arthroscopy provides positive long-term outcomes, improving symptoms and function while avoiding the need for hip replacement surgery in most cases, reports a study in The Journal of Bone & Joint Surgery.

3 May 2023

Unraveling Nature's Complexity with Molecular Imaging

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Ron Heeran, a speaker at the 2023 James L. Waters Symposium.

From Pittcon 1 May 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

Newly discovered protein may be pivotal for traumatic heterotopic ossification

A team led by UT Southwestern Medical Center researchers has discovered a protein that appears to be pivotal for traumatic heterotopic ossification (HO), a condition in which bone forms in muscles, tendons, and other soft tissues after traumatic injury or surgery.

19 Apr 2023

Study illuminates a mechanism to explain the 'vicious circle' of osteoarthritis

Osteoarthritis is a degenerative joint disease caused by the breakdown of cartilage that afflicts more than 35 million adults in the U.S.

11 Apr 2023

New model for proteomic cardiovascular risk assessment among chronic kidney disease patients

Chronic kidney disease (CKD) is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. Despite the disease's prevalence-;10 percent of individuals across the globe suffer from CKD-;there are limited tools for measuring cardiac risk for CKD patients, until now.

4 Apr 2023

Cartilage News and Research

Further Reading

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

Combination of techniques reveals molecular changes in osteoarthritis

Spicing up rheumatic disease treatment: Study explores role of herbs and spices in improving patients' condition

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Researchers develop protein biomarker panels to predict developmental dysplasia of the hip

Life-changing procedure using new aortic valve device clears way for patient in need of liver transplant and hip replacement

Injectable fatty acid copolymer ARA 3000 BETA shows therapeutic potential in treating osteoarthritis

Primary arthroscopy provides positive long-term outcomes for young adults with borderline hip dysplasia

Unraveling Nature's Complexity with Molecular Imaging

New injectable cell therapy shows promise for treating osteoarthritis

Newly discovered protein may be pivotal for traumatic heterotopic ossification

Study illuminates a mechanism to explain the 'vicious circle' of osteoarthritis

New model for proteomic cardiovascular risk assessment among chronic kidney disease patients

Meniscus-sparing surgeries in young athletes more effective in protecting cartilage from future damage

People with asthma or eczema more likely to develop osteoarthritis

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

AI-based design method synthesizes polymers that mimic blood plasma

Scientists discover how tendons and salivary glands develop in the jaw

New technique helps surgeons reconstruct more natural-looking nipples after mastectomy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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