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TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Excessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which accounts for 25% and 30% of deaths from cirrhosis and hepatocellular carcinoma. Impairment of Ca2+ influx and Ca2+-mediated signaling in ALD suggests that Ca2+ channels are important in ALD pathological progression.

16 Jan 2024

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

Nanotechnology's triple threat: Advancing precision cancer treatment

The design of tumor tissue-, cell-, and organelle-targeted cancer nanomedicines.

9 Aug 2023

Study provides insights into the molecular mechanism of Batten disease

Neuronal Ceroid Lipofuscinosis are a group of devastating neurodegenerative lysosomal storage disorders that begin in childhood. Mutations in CLN3 gene lead to a NCL called Batten disease, characterized by the progressive loss of vision, movement, and cognition.

6 Jul 2023

Are quaternary ammonium compounds associated with adverse environmental and health outcomes?

Researchers presented an overview of quaternary ammonium compounds and their environmental and human health concerns.

11 May 2023

Study suggests potential therapeutic targets for COVID-19-related neurological pathologies

In a recent study published in the journal Molecular & Cellular Proteomics, researchers analyzed the proteins in cerebrospinal fluid (CSF) samples obtained from African green monkeys and rhesus macaques infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 to understand the neurological manifestations of coronavirus disease 2019 (COVID-19).

9 Apr 2023

Scientists unearth some of the biological mechanisms behind ferroptosis

A team of researchers at Tohoku University has unearthed some of the biological mechanisms of ferroptosis, a recently discovered type of regulated cell death that is triggered by iron and the accumulation of lipid peroxidation - lipids that have undergone oxidative degeneration.

5 Apr 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Researchers examined the pathological impacts of the structural components of SARS-CoV-2 on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.

20 Dec 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

Johns Hopkins researchers uncover a possible target to treat sleep apnea

In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people.

31 Oct 2022

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

According to a recent study, substance P produced by the nociceptors present in the gut lining confers protection against inflammation and tissue damage by increasing the number of beneficial microbes.

19 Oct 2022

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

In a new study, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium cations (Ca2+) cations.

14 Oct 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

Cation News and Research

TRPC3 emerges as key player in preventing damage from alcohol-associated liver disease

Fox urine compound effectively repels flies through multisensory activation

Nanotechnology's triple threat: Advancing precision cancer treatment

Study provides insights into the molecular mechanism of Batten disease

Are quaternary ammonium compounds associated with adverse environmental and health outcomes?

Study suggests potential therapeutic targets for COVID-19-related neurological pathologies

Scientists unearth some of the biological mechanisms behind ferroptosis

The relationship between natural plant extracts and SARS-CoV-2

SARS-CoV-2 structural proteins trigger periodontal fibrosis

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Johns Hopkins researchers uncover a possible target to treat sleep apnea

Gut-innervating nociceptors found to regulate the intestinal microbiota and promote tissue protection

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

Licorice compounds proposed as effective candidates for treatment of COVID-19

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

SARS-CoV-2 RBD is a selective integrin agonist

Examining hypomagnesemia in critically ill patients with Acute Kidney Injury (AKI)

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Mushroom-derived compounds have potential for use as COVID-19 therapeutic

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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