Celecoxib News and Research

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UH College of Pharmacy secures CPRIT funding to fight familial adenomatous polyposis

The University of Houston College of Pharmacy is included in a $68.5 million funding package from the Cancer Prevention and Research Institute of Texas (CPRIT).

11 Mar 2024

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Novel multimodal analgesia protocol following total knee arthroplasty provides pain relief without opioids

A study led by Vinod Dasa, MD, Professor of Orthopaedics at LSU Health New Orleans School of Medicine, reports that a novel surgical pain management strategy following total knee arthroplasty (TKA), or total knee replacement, provided pain relief without opioids.

27 Feb 2023

Use of anti-inflammatory drugs by children may be associated with dental enamel defects

A study conducted at the University of São Paulo in Brazil and described in an article published in the journal Scientific Reports shows that anti-inflammatory drugs commonly taken by children may be associated with dental enamel defects (DEDs), currently seen in about 20% of children worldwide.

20 Dec 2022

Combination treatment does not slow radiographic spinal progression in radiographic axSpA patients

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that combining a nonsteroidal anti-inflammatory drug and TNF inhibitor did not significantly slow radiographic spinal progression in radiographic axial spondyloarthritis patients.

8 Nov 2022

Short-term NSAID use linked with first-time heart failure hospitalization in patients with type 2 diabetes

Short-term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a first-time hospitalization for heart failure in patients with type 2 diabetes, according to research presented at ESC Congress 2022.

23 Aug 2022

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study led by Cedars-Sinai Cancer investigators.

28 Mar 2022

Researchers overcome key challenge in creating sulfur-based medicines

A key technical challenge in creating new sulfur-based medicines has been overcome by scientists at Nanyang Technological University, Singapore (NTU Singapore), leading to the prospect of many new therapeutic 'weapons' in the fight against disease and illness.

15 Feb 2022

FDA's accelerated drug approval process plagued by missing efficacy data and questionable evidence

Since the US Food and Drug Administration established its accelerated approval pathway for drugs in 1992, nearly half of the 253 drugs authorized have not been confirmed as clinically effective, an investigation by The BMJ has found.

31 Jul 2021

Some COX inhibitors/NSAIDs increase COVID-19 severity

A startling new preprint research paper posted to the medRxiv server warns against the use of commonly used non-steroidal anti-inflammatory drugs (NSAIDs) belonging to the category of cyclooxygenase inhibitors (COX inhibitors) in patients with coronavirus disease 2019 (COVID-19).

22 Apr 2021

New pain management regimen reduced opioid exposure in trauma patients

A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth).

22 Jan 2021

FDA warns women about the risks of using NSAIDs in the second half of pregnancy

The U.S. Food and Drug Administration announced today in a Drug Safety Communication that it is requiring labeling changes for nonsteroidal anti-inflammatory drugs (NSAIDs).

15 Oct 2020

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Nine months into the global pandemic, which has infected more than 32 million people, there is still no approved effective and safe drug or vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Sep 2020

Scientists discover two anti-inflammatory drugs that inhibit COVID-19 infection

Since the outbreak of the COVID-19 pandemic and its rapid spread, the scientific community has been working on developing an effective treatment for the virus responsible for the disease.

27 May 2020

Large-scale enhanced recovery program after bariatric surgery improves patient outcomes

A large-scale implementation of a protocol to improve recovery of patients after weight-loss operations was found to reduce rates of extended hospitalization by almost half at 36 participating accredited bariatric surgery centers nationwide, according to a study published online ahead of print in the current issue of the journal Surgery for Obesity and Related Diseases.

24 Sep 2019

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

A team from Roswell Park Comprehensive Cancer Center is moving a new three-part strategy for treating advanced cancers forward with support from a U.S. Department of Defense grant to Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Rustum Family Professor for Molecular Therapeutics and Translational Research at the Buffalo, N.Y.-based cancer center.

18 Sep 2019

Celecoxib News and Research

UH College of Pharmacy secures CPRIT funding to fight familial adenomatous polyposis

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Novel multimodal analgesia protocol following total knee arthroplasty provides pain relief without opioids

Use of anti-inflammatory drugs by children may be associated with dental enamel defects

Combination treatment does not slow radiographic spinal progression in radiographic axSpA patients

Short-term NSAID use linked with first-time heart failure hospitalization in patients with type 2 diabetes

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Researchers overcome key challenge in creating sulfur-based medicines

FDA's accelerated drug approval process plagued by missing efficacy data and questionable evidence

Some COX inhibitors/NSAIDs increase COVID-19 severity

New pain management regimen reduced opioid exposure in trauma patients

FDA warns women about the risks of using NSAIDs in the second half of pregnancy

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Scientists discover two anti-inflammatory drugs that inhibit COVID-19 infection

Large-scale enhanced recovery program after bariatric surgery improves patient outcomes

Roswell Park moving three-pronged immunotherapy strategy forward with support from DoD grant

Big-data analysis finds new link between popular arthritis drug and heart valve calcification

Researchers report uncertainty around long-term effectiveness of medications to control knee osteoarthritis pain

UH pharmaceutical scientist developing new drug to treat children with rare genetic disorder

High-fat diet and systemic inflammation contribute to progression of prostate cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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