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Stem cell therapy improves radiation-induced cognitive impairment

Patients receiving cranial irradiation treatment for brain cancer may find the treatment life-saving, but often suffer progressive and debilitating cognitive detriments, including spatial learning and memory deficits. The cognitive deficits are a contributing factor to the often significant adverse impacts on the surviving patients' quality of life after radiation therapy. In an effort to improve post-irradiation cognitive impairment, scientists at the University of California, Irvine, and colleagues at Neuralstem, Inc. (Rockville, MD), have transplanted fetal stem cells into laboratory animals with radiation-induced cognitive impairments and found that this led to a number of cognitive improvements.

23 Aug 2013

Research findings lay foundation for regenerating damaged heart muscle

In the aftermath of a heart attack, cells within the region most affected shut down. They stop beating. And they become entombed in scar tissue. But now, scientists at the Gladstone Institutes have demonstrated that this damage need not be permanent-by finding a way to transform the class of cells that form human scar tissue into those that closely resemble beating heart cells.

23 Aug 2013

Scientists grow cells that line blood vessels from human iPSCs

In a scientific first, Harvard Stem Cell Institute scientists have successfully grown the cells that line the blood vessels-called vascular endothelial cells-from human induced pluripotent stem cells (iPSCs), revealing new details about how these cells function.

23 Aug 2013

New technique may convert cells from heart disease patients into heart muscle cells

Researchers have developed a new technique that might one day be used to convert cells from heart disease patients into heart muscle cells that could act as a personalized treatment for their condition.

23 Aug 2013

MFDCs have advantages over adult skin cells, including proliferation and differentiation

Multipotent fetal dermal cells (MFDCs) may be an ideal source for cell therapy for repairing damaged tissues and organs. Their performance is superior to that of adult dermal cells, said a research team in Italy that developed a cell isolation technique for MFDCs and subsequently published a study that appears as an early e-publication for the journal Cell Transplantation.

23 Aug 2013

Seven researchers to receive grants from ASTRO to advance radiation oncology research

The American Society for Radiation Oncology (ASTRO) has selected seven (7) leading researchers who will receive a total of $675,000 in awards and grants to advance radiation oncology research.

23 Aug 2013

Study shows how microbes cooperate with sex hormones to affect immune system

Females can mount more powerful immune responses than males, but the flip side of this enhanced protection against infections is a greater risk for autoimmune disorders. Shedding light on the underlying causes of the gender bias in autoimmune diseases, a study published by Cell Press August 22nd in the journal Immunity reveals that certain gut microbes prevalent in males can help protect them against type 1 diabetes.

23 Aug 2013

Researchers uncover how SARS coronavirus uses host cell to reproduce itself

UC Irvine infectious disease researchers have uncovered components of the SARS coronavirus - which triggered a major outbreak of severe acute respiratory syndrome in 2002-03 - that allow it to take over host cells in order to replicate.

23 Aug 2013

Navidea Biopharmaceuticals signs SPA agreements with FDA for NAV5001 Phase 3 program

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that it has reached agreement with the U.S. Food and Drug Administration for two special protocol assessments for the Company's pivotal Phase 3 program with NAV5001 as an aid in the differential diagnosis of Parkinsonian Syndromes from non-Parkinsonian tremor.

23 Aug 2013

MC1R mutation responsible for red hair phenotype also promotes cancer-causing pathway

A person's skin pigment, which determines hair color and skin tone, is influenced by the melanocortin-1 (MC1R) gene receptor. For the population's one to two percent of redheads, a mutation in MC1R accounts for their red hair color and typical light skin.

23 Aug 2013

Evotec And Jain Extend Research Collab In Skeletal Muscular Dystrophy

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22 Aug 2013

Novartis starts shipment of 2013-2014 seasonal influenza vaccines to US customers

Novartis announced today that it has begun shipment of its seasonal influenza vaccines to customers in the US market for the 2013-2014 season. Novartis plans to ship a minimum of 30 million doses of its influenza vaccines to the US market, including Fluvirin (Influenza Virus Vaccine), approved for use in people 4 years of age and older, and Flucelvax (Influenza Virus Vaccine), approved for use in adults 18 years of age and older.

22 Aug 2013

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

Two oral targeted drugs approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, according to results of a large international clinical trial led by researchers at Dana-Farber Cancer Institute.

22 Aug 2013

Medical investigators discover new aspect of gene-splicing process that produces mRNA

A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon Dreyfuss, PhD, and his team from the Perelman School of Medicine at the University of Pennsylvania, discovered an entirely new aspect of the gene-splicing process that produces messenger RNA (mRNA).

22 Aug 2013

Study: Mother's mitochondrial DNA seems to influence our own aging

As we age, our cells change and become damaged. Now, researchers at Karolinska Institutet and the Max Planck Institute for Biology of Aging have shown that aging is determined not only by the accumulation of changes during our lifetime but also by the genes we acquire from our mothers.

22 Aug 2013

People exposed to hot environments may develop Malignant hyperthermia

There is mounting evidence that some people who are susceptible to Malignant hyperthermia (MH) will develop MH when exposed to hot environments or with exercise.

22 Aug 2013

AMD associated with impaired lysosomal autophagy, study finds

A new study published in the prestigious PLoS One journal changes our understanding of the pathogenesis of age-related macular degeneration. The researchers found that degenerative changes and loss of vision are caused by impaired function of the lysosomal clean-up mechanism, or autophagy, in the fundus of the eye.

22 Aug 2013

UC Davis Health System develops new screening strategy for lethal stage of TB in Asia

More than 20,000 people in Pakistan are being tested for the potentially deadly stage of tuberculosis using a new strategy developed at UC Davis Health System to effectively detect the disease in children for the first time.

22 Aug 2013

Research suggests restricting calories may improve success of cancer treatment

New research suggests that restricting calories for a defined period of time may improve the success of cancer treatment, offering valuable new data on how caloric intake may play a role in programmed cancer cell death and efficacy of targeted cancer therapies. Study results were published online today in Blood, the Journal of the American Society of Hematology (ASH).

22 Aug 2013

Radiation Oncologist receives Young Investigator Award from PCF

Jefferson Radiation Oncologist, Nicole Simone, M.D., was recently awarded one of 21 Young Investigator Awards from the Prostate Cancer Foundation (PCF).

21 Aug 2013

Cell News and Research

Stem cell therapy improves radiation-induced cognitive impairment

Research findings lay foundation for regenerating damaged heart muscle

Scientists grow cells that line blood vessels from human iPSCs

New technique may convert cells from heart disease patients into heart muscle cells

MFDCs have advantages over adult skin cells, including proliferation and differentiation

Seven researchers to receive grants from ASTRO to advance radiation oncology research

Study shows how microbes cooperate with sex hormones to affect immune system

Researchers uncover how SARS coronavirus uses host cell to reproduce itself

Navidea Biopharmaceuticals signs SPA agreements with FDA for NAV5001 Phase 3 program

MC1R mutation responsible for red hair phenotype also promotes cancer-causing pathway

Evotec And Jain Extend Research Collab In Skeletal Muscular Dystrophy

Novartis starts shipment of 2013-2014 seasonal influenza vaccines to US customers

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

Medical investigators discover new aspect of gene-splicing process that produces mRNA

Study: Mother's mitochondrial DNA seems to influence our own aging

People exposed to hot environments may develop Malignant hyperthermia

AMD associated with impaired lysosomal autophagy, study finds

UC Davis Health System develops new screening strategy for lethal stage of TB in Asia

Research suggests restricting calories may improve success of cancer treatment

Radiation Oncologist receives Young Investigator Award from PCF

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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