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Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticles from combustion engines can activate viruses that are dormant in lung tissue cells. This is the result of a study by researchers of Helmholtz Zentrum München, a partner in the German Center for Lung Research, which has now been published in the journal 'Particle and Fibre Toxicology'. [More]
New research paves way for better strategies to diagnose and manage vascular graft infections

New research paves way for better strategies to diagnose and manage vascular graft infections

A rising prevalence of cardiovascular disease has generated substantial growth in the use of medical implants, such as vascular grafts. [More]
HUB and Dutch health insurance companies to test use of organoid technology for CF treatment

HUB and Dutch health insurance companies to test use of organoid technology for CF treatment

Hubrecht Organoid Technology (HUB), and the health insurance companies CZ, Zilveren Kruis, and Menzis announced today that they will start a €3 million validation trial for use of HUB Organoid Technology to test if it can be used to determine the response of Cystic Fibrosis (CF) patients to new drug therapies. [More]
Two research studies on new molecules could potentially treat Alzheimer's disease

Two research studies on new molecules could potentially treat Alzheimer's disease

This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer's disease. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Researchers working to develop pill for inherited bleeding disorders

Researchers working to develop pill for inherited bleeding disorders

Motivated by the tribulations of hemophilia patients and their families, researchers funded by the National Institute of Biomedical Imaging and Bioengineering are working to develop a pill to treat this serious inherited bleeding disorder. [More]
Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component. [More]
Researchers engineer promising live-attenuated RSV vaccine candidate

Researchers engineer promising live-attenuated RSV vaccine candidate

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance. [More]
Active ingredient of pungent substances slows growth of breast cancer cells

Active ingredient of pungent substances slows growth of breast cancer cells

Capsaicin, an active ingredient of pungent substances such as chilli or pepper, inhibits the growth of breast cancer cells. [More]
Research findings reveal new powerful role of sunlight on immunity

Research findings reveal new powerful role of sunlight on immunity

Sunlight allows us to make vitamin D, credited with healthier living, but a surprise research finding could reveal another powerful benefit of getting some sun. [More]
Researchers identify attractive drug candidate to target glioma tumors

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed. [More]
Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Lactate component responsible for anti-tumor effects of plasma medicine, research shows

Physical plasma is one of the four fundamental states of matter, together with solid, liquid, and gas, and can be completely or partially ionized (thermal/hot or non-thermal/cold plasma, respectively). [More]
A kit to facilitate the convenient measurement of FAO-driven respiration

A kit to facilitate the convenient measurement of FAO-driven respiration

AMSBIO has introduced the MitoXpress® Xtra Fatty Acid Oxidation (FAO) kit to facilitate the convenient measurement of FAO-driven respiration. [More]
Novel plasma medicine with anti-tumor effect discovered

Novel plasma medicine with anti-tumor effect discovered

Nagoya University researchers develop cold plasma-activated Ringer's solution for chemotherapy. The solution has anti-tumor effects in vitro and in vivo that derive from the lactate component. [More]
Research redefines role of Spop protein during bone development

Research redefines role of Spop protein during bone development

Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes -- a condition known as brachydactyly. T [More]
Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Discovered in the 1970s, tumor suppressors are among the most important proteins in the body. [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
Study identifies conditions required to further develop liver and pancreas cells

Study identifies conditions required to further develop liver and pancreas cells

AMSBIO reports on the recent publication in Nature Protocols1 by Dr Meritxell Huch** and co-workers which describes development of culture conditions that allow the long-term expansion of adult primary tissues from the liver and pancreas into self-assembling 3D organoid cultures. [More]
Particle Works develops hydrogel beads to enable 3D cell culture growth

Particle Works develops hydrogel beads to enable 3D cell culture growth

Particle Works – the nano- and microstructured material specialist – has developed a range of alginate and agarose hydrogel beads designed to enable three dimensional cell culture growth. [More]
Researchers discover molecular pathway that plays major role in maintaining normal kidney function

Researchers discover molecular pathway that plays major role in maintaining normal kidney function

Boston University researchers, in collaboration with Centers for Therapeutic Innovation at Pfizer Inc., have discovered a novel molecular pathway needed to regulate kidney podocytes--special octopus-like cells that are critical in maintaining normal kidney function. [More]
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