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Research redefines role of Spop protein during bone development

Research redefines role of Spop protein during bone development

Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes -- a condition known as brachydactyly. T [More]
Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Discovered in the 1970s, tumor suppressors are among the most important proteins in the body. [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
Study identifies conditions required to further develop liver and pancreas cells

Study identifies conditions required to further develop liver and pancreas cells

AMSBIO reports on the recent publication in Nature Protocols1 by Dr Meritxell Huch** and co-workers which describes development of culture conditions that allow the long-term expansion of adult primary tissues from the liver and pancreas into self-assembling 3D organoid cultures. [More]
Particle Works develops hydrogel beads to enable 3D cell culture growth

Particle Works develops hydrogel beads to enable 3D cell culture growth

Particle Works – the nano- and microstructured material specialist – has developed a range of alginate and agarose hydrogel beads designed to enable three dimensional cell culture growth. [More]
Researchers discover molecular pathway that plays major role in maintaining normal kidney function

Researchers discover molecular pathway that plays major role in maintaining normal kidney function

Boston University researchers, in collaboration with Centers for Therapeutic Innovation at Pfizer Inc., have discovered a novel molecular pathway needed to regulate kidney podocytes--special octopus-like cells that are critical in maintaining normal kidney function. [More]
Lonza’s RAFT 3D Cell Culture System helps researchers develop corneal models for research into blindness treatment

Lonza’s RAFT 3D Cell Culture System helps researchers develop corneal models for research into blindness treatment

Lonza’s RAFT 3D Cell Culture System has been used to develop corneal models for research into treatment for a painful and potentially blinding corneal disease. [More]
BBI Solutions to showcase Morffi signal enhancement technology at MEDICA 2016

BBI Solutions to showcase Morffi signal enhancement technology at MEDICA 2016

BBI Solutions will be showcasing its Morffi signal enhancement technology on Stand F26 in Hall 1 at MEDICA 2016. [More]
Stanford researchers discover new biological markers to measure progression of Huntington's disease

Stanford researchers discover new biological markers to measure progression of Huntington's disease

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington's disease (HD). [More]
FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

Amgen today announced that the U.S. Food and Drug Administration has approved the supplemental Biologics License Application for the expanded use of ENBREL (etanercept), making it the first and only systemic therapy to treat pediatric patients (ages 4-17) with chronic moderate-to-severe plaque psoriasis. [More]
Researchers create new culture model of human intestine to study inflammatory bowel disease

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk. [More]
Alcohol-free berry wine could potentially reduce effects of Type 2 diabetes

Alcohol-free berry wine could potentially reduce effects of Type 2 diabetes

Blueberries, and berries in general, are among foods labeled as "diabetes superfoods" by the American Association of Diabetes. Food science researchers at the University of Illinois have found that fermenting berries may improve their antidiabetic potential even more. [More]
Nova Bioprofile FLEX autosampler helps achieve significant productivity improvement via dynamic feeding media optimization

Nova Bioprofile FLEX autosampler helps achieve significant productivity improvement via dynamic feeding media optimization

Current industry practices for large-scale mammalian cell cultures typically employ a standard platform fed-batch process with fixed volume bolus feeding. Although widely used, these processes are unable to respond to actual nutrient consumption demands from the culture, which can result in accumulation of by-products and depletion of certain nutrients. [More]
Study shows metabolite concentration can be controlled in bioreactors using OPC enabled BioProfile FLEX analyser

Study shows metabolite concentration can be controlled in bioreactors using OPC enabled BioProfile FLEX analyser

Current initiatives within the biopharmaceutical industry to adopt PAT (Process Analytical Technology) approaches in manufacturing, include activities in early process development. [More]
AMSBIO add new range of human endothelial progenitor cells

AMSBIO add new range of human endothelial progenitor cells

AMSBIO has expanded its wide and varied catalogue of primary and progenitor cell types and media with a new range of human endothelial progenitor cells (EPC). [More]
Small RNA molecules could contribute to serious pregnancy complication, study finds

Small RNA molecules could contribute to serious pregnancy complication, study finds

A family of small RNA molecules affects the development of cells that give rise to the placenta - an organ that transfers oxygen and nutrients from mother to fetus -- in ways that could contribute to a serious pregnancy complication, UT Southwestern Medical Center researchers report. [More]
Scientists discover new option for treating malignant pleural mesothelioma

Scientists discover new option for treating malignant pleural mesothelioma

Researchers at the Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital have discovered a new option for treating malignant pleural mesothelioma. [More]
Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit The Cell Factory in collaboration with Women's and Children's Health Department of the University of Padua and the Padua University Hospital are developing therapies for inflammatory bowel disease (IBD) using extracellular vesicles (EVs). [More]
New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. [More]
AMSBIO announces new edition of its popular organoid culture handbook

AMSBIO announces new edition of its popular organoid culture handbook

AMSBIO announces an extended and updated edition of its popular Organoid Culture Handbook. Launched at the EMBO Symposium on Organoids: Modelling Organ Development and Disease in 3D Culture, the new 24-page handbook includes valuable information about the latest available products, protocols, example results and research paper citations. [More]
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