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CMC Biologics, OncoSynergy partner to develop novel potential treatment for Ebola

CMC Biologics, OncoSynergy partner to develop novel potential treatment for Ebola

CMC Biologics and OncoSynergy have entered into an agreement for process development and GMP manufacture of OS2966 – a novel potential treatment for Ebola. The investigational drug candidate, designed to inhibit a major cellular adhesion receptor (CD29) that is fundamental for progression of aggressive and resistant cancer tumors, was granted orphan drug designation by the U.S. FDA earlier this year in the treatment of glioblastoma. [More]
Penn study has implications for developing new cell-based treatments for skin disease

Penn study has implications for developing new cell-based treatments for skin disease

As the main component of connective tissue in the body, fibroblasts are the most common type of cell. Taking advantage of that ready availability, scientists from the Perelman School of Medicine at the University of Pennsylvania, the Wistar Institute, Boston University School of Medicine, and New Jersey Institute of Technology have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells. [More]
AMSBIO announces DNA-In™ Neuro Transfection Reagent

AMSBIO announces DNA-In™ Neuro Transfection Reagent

AMSBIO announces DNA-In™ Neuro- a new generation transfection reagent developed specifically for maximum nucleic acid delivery into neurons, typically achieving a 2-fold or greater improvement in efficiency over currently available competing reagents. [More]
Potential new active substances for treating dengue virus

Potential new active substances for treating dengue virus

Researchers from Johannes Gutenberg University Mainz and the Julius Maximilian University of Würzburg are proposing potential new active substances for treating the dengue virus. Just like Ebola, dengue fever is also caused by a virus for which there is currently no cure and no vaccine and can be fatal. [More]
Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Long known for its ability to help organisms successfully adapt to environmentally stressful conditions, the highly conserved molecular chaperone heat-shock protein 90 (HSP90) also enables estrogen receptor-positive (ER+) breast cancers to develop resistance to hormonal therapy. [More]
Amgen announces new data from BLINCYTO Phase 2 study for treatment of patients with ALL

Amgen announces new data from BLINCYTO Phase 2 study for treatment of patients with ALL

Amgen today announced that new data from a pivotal Phase 2 study evaluating BLINCYTO (blinatumomab) for the treatment of adult patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia (ALL) was presented at the 56th American Society of Hematology Annual Meeting and Exposition. [More]
Amgen's XGEVA (denosumab) receives FDA approval for treatment of hypercalcemia of malignancy

Amgen's XGEVA (denosumab) receives FDA approval for treatment of hypercalcemia of malignancy

Amgen today announced that the U.S. Food and Drug Administration has approved a new indication for XGEVA (denosumab) for the treatment of hypercalcemia of malignancy (HCM) refractory to bisphosphonate therapy. [More]

Cytation™ 5 Cell Imaging Multi-Mode Reader to be introduced by BioTek at ASCB 2014

Join BioTek Instruments as they introduce the Cytation™ 5 Cell Imaging Multi-Mode Reader at the ASCB 2014 Conference and Exhibition to be held December 6-10 in Philadelphia, Pennsylvania. BioTek’s “Think Possible” philosophy is reflected in their microplate-based imaging, detection, liquid handling and automation solutions and the company will showcase their newest innovations at Booth #349. [More]
SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate against the very similar functional counterplayer FKBP52. [More]
Cultrex® Embryoid Body Formation Kit introduced by AMSBIO

Cultrex® Embryoid Body Formation Kit introduced by AMSBIO

AMSBIO, experts in extracellular matrices, have introduced the Cultrex® Embryoid Body Formation Kit to generate consistent, reproducible and identical in size embryoid bodies. It has been qualified to form embryoid bodies from human pluripotent stem cells. Embryoid bodies are finding increasing use in regenerative medicine, in-vitro screening and as a model of embryonic development. [More]
Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Automated biospecimen thawing: an interview with Dr Rolf Ehrhardt, CEO of BioCision

Surprisingly, even with decades of cryopreservation research, little progress has been made in the way frozen biospecimens are thawed. It’s still very common for researchers and clinicians to thaw cells and other frozen biological samples in a variety of manual ways ... [More]
Instron collaborates with BRTI Life Sciences on unique biomimetic hydrogel for the tissue engineering market

Instron collaborates with BRTI Life Sciences on unique biomimetic hydrogel for the tissue engineering market

Instron, a leading provider of testing equipment designed to evaluate mechanical properties of materials and components, is collaborating with Dr. John Brekke at BRTI Life Sciences in Duluth, Minnesota. [More]
SRY protein alters specific gender-related tissue in males before birth

SRY protein alters specific gender-related tissue in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges. [More]
New test can detect bloodstream infection with unprecedented speed, sensitivity

New test can detect bloodstream infection with unprecedented speed, sensitivity

A new bloodstream infection test created by UC Irvine researchers can speed up diagnosis times with unprecedented accuracy, allowing physicians to treat patients with potentially deadly ailments more promptly and effectively. [More]
AMSBIO signs strategic marketing agreement with Luxcel Biosciences

AMSBIO signs strategic marketing agreement with Luxcel Biosciences

AMSBIO has signed a strategic marketing agreement with Luxcel Biosciences to distribute their range of 96- and 384-well phosphorescence and fluorescence based assays. [More]

New multi-specimen perfusion bioreactor for reliable tissue growth introduced by Bose

Bose Corporation has introduced the 3DCulturePro™ system, a new multi-specimen perfusion bioreactor designed for biologists, biomedical researchers and scientists who require reproducible and reliable tissue growth. The 3DCulturePro system supports cell growth and 3D tissue culture in an easy-to-use, scalable configuration. [More]
High-absorption BCM-95 Curcumin can reduce spread of cancer cells

High-absorption BCM-95 Curcumin can reduce spread of cancer cells

A recently published cellular study on colorectal cancer showed that high-absorption BCM-95 Curcumin is able to reduce the spread of cancer cells and potentially increase the effectiveness of chemotherapy in the treatment of advanced colon cancer. [More]
FDA accepts Amgen's evolocumab BLA for review

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol. [More]
New model explains how immune cells recognize, destroy bacteria

New model explains how immune cells recognize, destroy bacteria

The innate immune system serves as the body's specialized armed forces division, comprised of a host of defense mechanisms used to battle bacterial infections. Among the system's warriors are white blood cells including the specialized macrophages, which maintain constant surveillance for foreign intruders or pathogens, functioning as the body's first line of defense, poised to attack at barrier sites including the skin, lungs and intestines. [More]
UF Health researcher finds way to grow human norovirus

UF Health researcher finds way to grow human norovirus

Noroviruses are pernicious intestinal viruses. They cause violent vomiting and diarrhea, and people ill with the virus remain contagious up to three days after they seem to recover. [More]