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Elusive brain receptor may play vital role in death of neurons from neurological diseases

Elusive brain receptor may play vital role in death of neurons from neurological diseases

Strokes, seizures, traumatic brain injury and schizophrenia: these conditions can cause persistent, widespread acidity around neurons in the brain. But exactly how that acidity affects brain function isn't well understood. [More]
International researchers make crucial discovery on formation, growth of blood vessels

International researchers make crucial discovery on formation, growth of blood vessels

As blood vessels grow, the cells that compose them must make a choice between forming side-branches or expanding the vessel surface and increasing its diameter. Now Prof. Holger Gerhardt at the Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association and his international research teams have made a crucial disovery about this process: the cells can behave as a collective, moving in the same direction together. [More]
Beckman Coulter Life Sciences to unveil Vi-CELL MetaFLEX for bioprocessing market at INTERPHEX 2016

Beckman Coulter Life Sciences to unveil Vi-CELL MetaFLEX for bioprocessing market at INTERPHEX 2016

Beckman Coulter Life Sciences will unveil a fast, low sample volume bioanalyte analyzer, the Vi-CELL MetaFLEX, at INTERPHEX 2016. This year’s event, showcasing pharmaceutical and bioprocessing innovation, is being held in the Jacob K. Javits Convention Center, New York, April 26-28 2016. [More]
Lab-grown mini-brains shed light on health crisis posed by Zika virus in fetal brains

Lab-grown mini-brains shed light on health crisis posed by Zika virus in fetal brains

Studying a new type of pinhead-size, lab-grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized stem cells that build its outer layer, the cortex. [More]
Drugs that block NOTCH signaling in many cancers could be effective against ACC

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Using a novel cell culture approach, Yale Cancer Center researchers have discovered critical vulnerabilities in adenoid cystic carcinoma (ACC), a rare and lethal glandular cancer with a high recurrence rate and few treatment options. [More]
Novel method could help analyze GWAS results for sporadic diseases

Novel method could help analyze GWAS results for sporadic diseases

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies can contribute to sporadic Parkinson's disease (PD). The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer. [More]
Reducing hair loss during chemotherapy: an interview with Richard Paxman

Reducing hair loss during chemotherapy: an interview with Richard Paxman

The basic principle of chemotherapy is to damage the mitotic and metabolic processes in the cancer cells. The chemotherapy doesn't just target the cancer cells, it also targets the healthy cells, specifically ones that are rapidly dividing - our hair follicles are also rapidly dividing. We see damage to those hair cells, which then causes the hair to fall out. [More]
Researchers aim to improve current procedures for predicting outcome of prostate cancer

Researchers aim to improve current procedures for predicting outcome of prostate cancer

Researchers are working to find a way to determine how serious prostate cancer is when first diagnosed to avoid unnecessary treatments, which can cause life long side effects and even death. [More]
Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

Innovative nano-therapy treatment can fight chronic inflammatory disorders, cancer

For an innovative treatment, which allows to selectively direct nanoparticles of iron oxide into cell targets in the blood to fight chronic inflammatory disorders or cancer that was successfully tested in a cell culture and animal models, Dr. Andrea de Vizcaya Ruiz, was awarded with the Innovation Award in Bionanotechnology Cinvestav-Neolpharma 2015. [More]
Study shows epidermal growth factor negatively regulates shedding of epithelial cells

Study shows epidermal growth factor negatively regulates shedding of epithelial cells

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. Altered shedding is associated with multiple disorders, ranging from inflammatory bowel disease (IBD) to colorectal cancer. [More]
LMU-led researchers define previously unknown signaling pathway that triggers inflammation

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

Using a combination of newly developed methods, researchers led by Ludwig-Maximilians-Universitaet (LMU) in Munich immunologist Veit Hornung have defined a previously unknown pathway that triggers inflammation. [More]
Researchers develop new technique to study blood vessel inflammation

Researchers develop new technique to study blood vessel inflammation

Nanotechnology has led to better diagnostic techniques and more effective treatments for a variety of illnesses. Tiny devices measuring between 1 and 100 micrometers--one micrometer is equal to one millionth of a meter--enable scientists to observe cell activity and deliver drugs to individual cells--a breakthrough that is on the verge of revolutionizing precision medicine for treatment of diseases such as cancer. [More]
Japanese scientists decode sugar molecule linked to muscular dystrophy

Japanese scientists decode sugar molecule linked to muscular dystrophy

A group of Japanese scientists have succeeded in decoding a sugar molecule and clarifying a mechanism linked to muscular dystrophy. Their discovery has potential implications for muscular dystrophy treatment. The results of their research were published in the journal Cell Reports on February 25, 2016 EST. [More]
Scientists provide overview of most promising compounds to combat prostate cancer

Scientists provide overview of most promising compounds to combat prostate cancer

Scientists from MIPT (Moscow Institute of Physics and Technology), MSU (Moscow State University), and National University of Science and Technology “MISIS” provided an overview of the most promising compounds which can be used as medications for prostate cancer. [More]
Novel approach to cancer risk assessment maximizes public health benefits

Novel approach to cancer risk assessment maximizes public health benefits

Edward Calabrese, the University of Massachusetts Amherst environmental toxicologist who has been an outspoken critic of the current linear no-threshold (LNT) approach to risk assessment for radiation and toxic chemicals, now proposes a new approach integrating LNT with hormetic dose-response models. [More]
Specialized gene editing system paves way to eventual cure for HIV patients

Specialized gene editing system paves way to eventual cure for HIV patients

A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS. [More]
Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry, investigators at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD). [More]
Panasonic introduces new MCO-170M multi gas incubators to optimise cell culture efficiency and productivity

Panasonic introduces new MCO-170M multi gas incubators to optimise cell culture efficiency and productivity

Panasonic’s new MCO-170M multi gas incubators provide outstanding quality and performance alongside advanced O2 and CO2 control to maximise cell culture efficiency and optimise results and reproducibility. [More]
Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapour revealed no activity in cells exposed to vapour from Vype ePen, a commercially available e-cigarette. [More]
PKM2 enzyme plays major role in early steps of wound healing

PKM2 enzyme plays major role in early steps of wound healing

An enzyme involved in glucose metabolism in cells plays a major role in the early steps of wound healing, a finding that could lead to new therapeutic approaches for wound care, according to researchers at Georgia State University. [More]
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