Centrioles News and Research

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Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain various specialized structures - such as the nucleus, mitochondria or peroxisomes - known as "organelles''.

12 Apr 2024

Newly identified process keeps some immune cells on their toes

Cancer cells use an unusual mechanism to migrate into new tissue and form metastases there. The same process probably also keeps some immune cells on their toes.

14 Oct 2022

New discovery could lead to the development of therapeutic approaches for retinitis pigmentosa

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness.

17 Jun 2022

Researchers identify γ-tubulin ring complex to be responsible for providing centriole stability

Centrioles are cylindrical structures involved in the generation of microtubules-;fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes.

1 Nov 2021

Discovery opens door to new diagnostics and therapeutic strategies for male infertility

Scientists at The University of Toledo discovered new movement in sperm that provides innovative avenues for diagnostics and therapeutic strategies for male infertility.

28 Jun 2021

New method could advance efforts to find drugs that kill breast cancer cells

Scientists at Johns Hopkins Medicine and the University of Oxford say they have found a new way to kill some multiplying human breast cancer cells by selectively attacking the core of their cell division machinery.

10 Sep 2020

Researchers use new approach to unravel the mechanisms that lie behind tetraploidy

Cell division is a fundamental process that organisms need to reproduce, grow, and make repairs. But when an error disrupts this complex biological process, cellular abnormalities can lead to diseases, such as cancer, where cells are enabled to grow and divide out of control.

25 Jul 2020

Study provides better understanding of mechanisms that limit cilia number in cells

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes.

30 Dec 2019

Exciting study shows how centrioles center the process of cell division

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells.

12 Jul 2019

Researchers discover important features of tumor cells that may help fight cancer

A research team led by Mónica Bettencourt Dias, from Instituto Gulbenkian de Ciência, discovered important features of cancer cells that may help clinicians fighting cancer.

28 Mar 2018

Researchers discover earliest-acting protein in C-elegans that plays key role in cell division

Researchers from three U.S. universities have identified, using roundworms, the earliest-acting protein known to duplicate the centriole, a tiny cylinder-shaped structure that is a key component of the machinery that organizes cell division in animals.

31 Jan 2017

FAU researchers identify endogenous process that controls reproduction of cardiac muscle cells

Heart failure is the most common cause of death worldwide. The main reason for this is that damage to the human heart causes cardiac muscle cells to die, which in turn leads to reduced heart function and death. However, this is not the case for zebrafish or amphibians. If their hearts become damaged and cardiac muscle cells die, their remaining cardiac muscle cells can reproduce, allowing the heart to regenerate.

7 Aug 2015

Orc1 mutations may explain pathology in manifestations of Meier-Gorlin syndrome

Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise to a particularly extreme version of dwarfism, small brain size, and other manifestations of abnormal growth which generally characterize that rare condition.

1 Aug 2012

Florida State University researcher explores role of key protein in cell division

A Florida State University researcher has identified the important role that a key protein plays in cell division, and that discovery could lead to a greater understanding of stem cells.

16 Jun 2010

New insight into human ciliopathy

In the September 1st issue of G&D, Dr. Karen Oegema (UCSD) and colleagues identify the molecular basis of the lethal developmental disorder, hydrolethalus syndrome, and reveal that hydrolethalus syndrome actually belongs to the emerging class of human ciliopathy diseases.

4 Aug 2009