Cerebral Palsy News and Research RSS Feed - Cerebral Palsy News and Research

The term cerebral palsy refers to any one of a number of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination but don’t worsen over time. Even though cerebral palsy affects muscle movement, it isn’t caused by problems in the muscles or nerves. It is caused by abnormalities in parts of the brain that control muscle movements. The majority of children with cerebral palsy are born with it, although it may not be detected until months or years later. The early signs of cerebral palsy usually appear before a child reaches 3 years of age. The most common are a lack of muscle coordination when performing voluntary movements (ataxia); stiff or tight muscles and exaggerated reflexes (spasticity); walking with one foot or leg dragging; walking on the toes, a crouched gait, or a “scissored” gait; and muscle tone that is either too stiff or too floppy. A small number of children have cerebral palsy as the result of brain damage in the first few months or years of life, brain infections such as bacterial meningitis or viral encephalitis, or head injury from a motor vehicle accident, a fall, or child abuse.
CUMC receives $7M to help establish Weinberg Family Cerebral Palsy Center

CUMC receives $7M to help establish Weinberg Family Cerebral Palsy Center

Seeking to bridge the transition from pediatric to adult care for people living with cerebral palsy, Debby and Peter A. Weinberg, with several of their family members and friends, have given more than $7 million to help establish the Weinberg Family Cerebral Palsy Center at Columbia University Medical Center (CUMC). [More]
Low blood flow to the premature brain disrupts cells' ability to fully mature

Low blood flow to the premature brain disrupts cells' ability to fully mature

Physician-scientists at Oregon Health & Science University Doernbecher Children's Hospital are challenging the way pediatric neurologists think about brain injury in the pre-term infant. In a study published online in the Jan. 16 issue of Science Translational Medicine, the OHSU Doernbecher researchers report for the first time that low blood and oxygen flow to the developing brain does not, as previously thought, cause an irreversible loss of brain cells, but rather disrupts the cells' ability to fully mature. [More]

State roundup: Medicaid costs could affect state surpluses; Calif. gets 'C' for dental care

In Tennessee, Republican governor Bill Haslam has said that much of the state's $580 million surplus is already spent. Obamacare is expected to increase enrollment in TennCare, the state's Medicaid program, by more than 60,000 Tennesseans. ... At the same time, Texas has a $8.8 billion surplus and more than $8 billion in its rainy day fund, but faces a staggering $4.3 billion hole in its Medicaid budget. [More]
Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the resubmission of the New Drug Application (NDA) for sugammadex sodium injection has been accepted for review by the U.S. Food and Drug Administration (FDA). Merck expects the FDA’s review to be completed in the first half of 2013. [More]

Acorda Therapeutics acquires Neuronex

Acorda Therapeutics, Inc. today announced that the Company has completed the acquisition of Neuronex, Inc., a privately held company developing a nasal spray formulation of diazepam. Under the terms of the agreement, Acorda paid $6.8 million to Neuronex to complete the acquisition. [More]

Roundup: Minn. court rules relatives deserve same pay for personal care attendant work; Colo. governor wants $18.5M for expanded mental health care

The state's effort to reduce pay for some personal care attendants has hit a snag. The Minnesota Appeals Court ruled Monday that the state's attempt to pay PCAs who care for relatives 20 percent less than other personal care attendants is unconstitutional. "They have the same training, they have the same experience, they're limited to the same number of maximum hours," said attorney David Bradley Olsen, who represents 11 agencies and several personal care assistants who sued over the matter. [More]

Access4Kids benefits children with fine motor impairments

Imagine not being able to touch a touch-screen device. Tablets and smartphones-with all their educational, entertaining and social benefits-would be useless. Researchers at Georgia Tech are trying to open the world of tablets to children whose limited mobility makes it difficult for them to perform the common pinch and swipe gestures required to control the devices. [More]
New genetic process could provide novel target for treatment of neurodevelopmental disorders

New genetic process could provide novel target for treatment of neurodevelopmental disorders

Researchers at the Douglas Mental Health University Institute, have discovered a new genetic process that could one day provide a novel target for the treatment of neurodevelopmental disorders, such as intellectual disability and autism. [More]

Speech problems affect half of all children with cerebral palsy

Speech disorders are highly prevalent among children with cerebral palsy and vary according to the nature and timing of the brain injury, an investigation by Swedish researchers has found. [More]
UCB to sponsor key sets of VIMPAT C-V data at 66th American Epilepsy Society annual meeting

UCB to sponsor key sets of VIMPAT C-V data at 66th American Epilepsy Society annual meeting

UCB, a global biopharmaceutical company focusing on CNS and immunology treatment and research, is sponsoring key sets of VIMPAT® (lacosamide) C-V data at the 66th Annual Meeting of the American Epilepsy Society (AES) in San Diego, Calif., November 30 - December 4. [More]

Parents with disabilities face challenges gaining custody of children

Millions of Americans with disabilities have gained innumerable rights and opportunities since Congress passed landmark legislation on their behalf in 1990. [More]
Inovio's SynCon DNA vaccine effective at inducing CD8+ T cell responses specific to CMV

Inovio's SynCon DNA vaccine effective at inducing CD8+ T cell responses specific to CMV

Inovio Pharmaceuticals, Inc. announced today that testing of multiple synthetic vaccine constructs for cytomegalovirus (CMV) induced robust T cells in mice, demonstrating the potential for a SynCon DNA vaccine to treat this virus that causes infant death and congenital abnormalities, is associated with cerebral palsy and brain tumors, and is the most common viral infection in organ transplant recipients. CMV is also associated with numerous inflammatory diseases and cancers, and is implicated in hypertension, a major risk factor for cardiovascular diseases. [More]

First Edition: November 26, 2012

Today's headlines include a range of stories regarding the future of the "fiscal cliff" negotiations as well as reports about the strategies that might now be used by health law opponents. [More]
Generic scale compares manual ability across diagnoses

Generic scale compares manual ability across diagnoses

Researchers have developed a generic manual ability scale unbiased by diagnosis that could allow quantitative comparisons of manual ability between diagnostic groups. [More]

Researchers combine robotics, machine learning and brain imaging to assist infants with CP

Learning to crawl comes naturally for most infants, but those with cerebral palsy lack the muscle strength and coordination to perform the 25 individual movements required for crawling. With a $1.135 million, three-year grant from the National Science Foundation's National Robotics Initiative, University of Oklahoma researchers from the Norman and Health Sciences Center campuses are combining robotics, machine learning and brain imaging to assist infants with CP with the challenging, life-altering skill. [More]
Researchers unlock complex cellular mechanics that instruct glial progenitor cells to divide

Researchers unlock complex cellular mechanics that instruct glial progenitor cells to divide

In a new study appearing this month in the Journal of Neuroscience, researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This discovery overcomes a significant technical hurdle to potential human stem cell therapies; ensuring that an abundant supply of cells is available to study and ultimately treat people with diseases. [More]
HSS announces opening of new Lerner Children's Pavilion

HSS announces opening of new Lerner Children's Pavilion

The new Pavilion within the #1 hospital for orthopedics in the country affirms HSS' longstanding commitment to championing children and caring for their musculoskeletal conditions. [More]
GAPPS announces five new projects for prevention of preterm births

GAPPS announces five new projects for prevention of preterm births

Five innovative research projects aiming to prevent premature birth were announced today by the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS), an initiative of Seattle Children's. [More]
Transplanted neural stem cells able to produce new myelin in children with PMD

Transplanted neural stem cells able to produce new myelin in children with PMD

A Phase I clinical trial led by investigators from the University of California, San Francisco and sponsored by Stem Cells Inc., showed that neural stem cells successfully engrafted into the brains of patients and appear to have produced myelin. [More]
Researchers discover mechanism by which magnesium reduces cytokine production

Researchers discover mechanism by which magnesium reduces cytokine production

Magnesium sulfate is given to many pregnant women to treat preterm labor and preeclampsia and was recently shown to prevent cerebral palsy; however little is known about how it works. Researchers at Case Western Reserve University School of Medicine recently discovered the mechanism by which magnesium reduces the production of cytokines. [More]