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Cerebrovascular disease is a group of brain dysfunctions related to disease of the blood vessels supplying the brain. Hypertension is the most important cause; it damages the blood vessel lining, endothelium, exposing the underlying collagen where platelets aggregate to initiate a repairing process which is not always complete and perfect. Sustained hypertension permanently changes the architecture of the blood vessels making them narrow, stiff, deformed, uneven and more vulnerable to fluctuations in blood pressure.

FDA approves sNDA for pediatric autism drug ABILIFY

20. November 2009 23:40
Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co., Ltd. announced today that the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for ABILIFY® (aripiprazole) for the treatment of irritability associated with autistic disorder in pediatric patients ages 6 to 17 years, including symptoms of aggression towards others, deliberate self-injuriousness, temper tantrums, and quickly changing moods. [More]

Obese patients less likely to achieve cholesterol and blood pressure control

26. October 2009 01:10
Obese patients taking medications to lower their blood pressure and cholesterol levels are less likely to reach recommended targets for these cardiovascular disease risk factors than their normal weight counterparts, according to new research presented at the 2009 Canadian Cardiovascular Congress hosted by the Canadian Cardiovascular Society and the Heart and Stroke Foundation of Canada. [More]

Vanda Pharmaceuticals announces its agreement with Novartis Pharma AG

14. October 2009 02:14
Vanda Pharmaceuticals Inc. announced today that it has entered into an agreement with Novartis Pharma AG to commercialize and develop Fanapt(TM) (iloperidone), Vanda's anti-psychotic, in the U.S. and Canada. Fanapt(TM) was approved by the U.S. Food and Drug Administration on May 6, 2009 for the acute treatment of schizophrenia in adults. [More]

Beth Israel Deaconess Medical Center neurologist elected as ANA Honorary Member

8. October 2009 06:49
Louis R. Caplan, MD, Senior Neurologist at Beth Israel Deaconess Medical Center (BIDMC) and a leader in the treatment and research of strokes, has been elected an Honorary Member of the American Neurological Association (ANA). As the organization's highest honor, Honorary Membership is reserved for select individuals who have made unique contributions to neurology and neurological science throughout their careers. [More]

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Rush University receives grants to study how epigenomic changes define cognitive decline

1. October 2009 05:34
The National Institutes of Health has awarded Rush University Medical Center approximately $5.5 million in grants to study how epigenetic changes - chemical modifications to genes that result from diet, aging, stress, or environmental exposures - define and contribute to memory formation and cognitive decline. Results from the studies could profoundly alter the way the medical community understands, diagnoses, and treats Alzheimer's disease, according to the researchers. [More]

Study on how epigenetic changes contribute to congnitive decline

28. September 2009 07:18
The National Institutes of Health has awarded Rush University Medical Center approximately $5.5 million in grants to study how epigenetic changes - chemical modifications to genes that result from diet, aging, stress, or environmental exposures - define and contribute to memory formation and cognitive decline. Results from the studies could profoundly alter the way the medical community understands, diagnoses, and treats Alzheimer's disease, according to the researchers. [More]

Final results of SAPHRIS clinical study released

14. September 2009 07:51
Schering-Plough Corporation today reported final results of a SAPHRIS(R) (asenapine) long-term schizophrenia relapse prevention clinical study. [More]

Newly established Edward Neurosciences Institute to provide advanced stroke care in Chicago

11. September 2009 06:48
Edward Hospital announced today that it has established the Edward Neurosciences Institute in affiliation with the Northwestern Medical Faculty Foundation to bring the highest level of stroke care in the world to the west and southwest suburbs of Chicago. [More]

The Kyoto Heart study shows positive effect of valsartan on cardiovascular outcome

2. September 2009 06:43
The KYOTO HEART Study, which took place in Japan between January 2004 and January 2009, shows that the addition of valsartan to conventional antihypertensive treatment to improve blood pressure control is associated with an improved cardiovascular outcome in Japanese hypertensive patients at high risk of CVD events. [More]

Study reveals that valsartan prevents cardiovascular events in high-risk hypertensive Japanese patients

2. September 2009 04:23
The KYOTO HEART Study, which took place in Japan between January 2004 and January 2009, shows that the addition of valsartan to conventional antihypertensive treatment to improve blood pressure control is associated with an improved cardiovascular outcome in Japanese hypertensive patients at high risk of CVD events. [More]

Low level exposure to carbon dioxide leads to increased risk of hospitalization in older people

1. September 2009 01:48
Exposure to carbon monoxide, even at levels well below national limits, is associated with an increased risk of hospitalization for the elderly with heart problems, according to a study published today in Circulation: Journal of the American Heart Association. [More]

Increased risk of stroke and transient ischemic attack in survivors of Hodgkin lymphoma

17. June 2009 20:57
Patients treated for Hodgkin lymphoma with radiation therapy have a substantially higher risk of stroke, according to a new study published June 17 online in the Journal of the National Cancer Institute. [More]

Skin disease psoriasis associated with cardiovascular disease and increased mortality

16. June 2009 02:39
The skin disease psoriasis is associated with atherosclerosis (a buildup of plaque in the arteries) characterized by an increased prevalence of ischemic heart disease, cerebrovascular disease, peripheral artery disease and an increased risk of death, according to a report in the June issue of Archives of Dermatology. [More]

Aspirin lowers risk of stroke in peripheral artery disease

12. May 2009 17:07
An analysis of previous studies indicates that among patients with peripheral artery disease, aspirin use is associated with a statistically nonsignificant decrease in the risk of a group of combined cardiovascular events (nonfatal heart attack, nonfatal stroke, and cardiovascular death), but is associated with a significant reduction in the risk of one of these events, nonfatal stroke, although the findings may be limited by the lack of a large study population, according to an article in the May 13 issue of JAMA, the Journal of the American Medical Association. [More]

Sinobiopharma announces Chinese approval of Perindopril

12. May 2009 07:44
Sinobiopharma, Inc. has announced that it has received approval from the Chinese State Food and Drug Administration (SFDA) to manufacture and market its formulation of Perindopril, an anti-hypertension drug. [More]
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