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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid. Cholesterol also comes from eating foods taken from animals such as egg yolks, meat, and whole-milk dairy products. Too much cholesterol in the blood may build up in blood vessel walls, block blood flow to tissues and organs, and increase the risk of developing heart disease and stroke.
Resistant starch in diet improves balance of gut bacteria, decreases cholesterol

Resistant starch in diet improves balance of gut bacteria, decreases cholesterol

The secret ingredient is in the flour, but its impact lies within the gut. Adding resistant starch to the diets of people with metabolic syndrome can improve bacteria in the gut, according to research from South Dakota State University. [More]
Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD

Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD

Regular consumption of seafood and plant-based omega-3 polyunsaturated fatty acids could help lower the risk of fatal coronary heart disease, confirm findings from a pooled analysis of 19 studies. [More]
Study links alpha-defensin genes to IgA nephropathy risk

Study links alpha-defensin genes to IgA nephropathy risk

A gene which forms part of our body's first line of defence against infection may be associated with an increased risk with a type of kidney disease, research involving academics at The University of Nottingham has discovered. [More]
Circulating microRNAs may help predict risk for myocardial infarction

Circulating microRNAs may help predict risk for myocardial infarction

When you visit your general practitioner you can get your blood analyzed for cholesterol and triglycerides, to get an idea of your risk for cardiovascular disease. With additional information about BMI, smoking habits and blood pressure, this can be used to calculate your 10-year risk for cardiovascular disease. [More]
Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

Tiny doses of anti-HIV drug may be effective for treating Alzheimer's disease

For a promising pathway to treating Alzheimer's patients, "aim here." That's what National Institute of Standards of Technology researchers advised collaborators hunting for molecules that, by linking to a normally occurring enzyme, rev up the brain's capacity for clearing cholesterol--a boost associated with improvements in memory and other benefits in animal studies. [More]
Pharmacotherapy reduces conduction system disease risk

Pharmacotherapy reduces conduction system disease risk

Lisinopril therapy significantly reduces incident conduction system disease, indicates a post-hoc analysis of ALLHAT data. [More]
The scent dogs smell on diabetics’ breath could offer key to new tests

The scent dogs smell on diabetics’ breath could offer key to new tests

An increase in the level of the chemical isoprene may be the warning sign some dogs can detect in the breath of patients with type 1 diabetes who are reaching risky low levels of blood sugar, according to research by the University of Cambridge. [More]
Blood levels of omega-3s fatty acids linked to lower risk of deadly heart attacks

Blood levels of omega-3s fatty acids linked to lower risk of deadly heart attacks

Blood levels of seafood and plant-based omega-3 fatty acids are moderately associated with a lower risk of dying from heart attacks, according to a new epidemiological study, published today in JAMA Internal Medicine, led by Liana C. Del Gobbo, Ph.D., a postdoctoral research fellow in the division of cardiovascular medicine at Stanford University School of Medicine and senior author Dariush Mozaffarian, M.D., Dr.P.H., dean of the Friedman School of Nutrition Science and Policy at Tufts University in Boston. [More]
Older adults with high LDL-C live longer than peers with low levels of same cholesterol, say experts

Older adults with high LDL-C live longer than peers with low levels of same cholesterol, say experts

A University of South Florida professor and an international team of experts have found that older people with high levels of a certain type of cholesterol, known as low-density lipoprotein (LDL-C), live as long, and often longer, than their peers with low levels of this same cholesterol. [More]
Researchers engineer revolutionary new approach to combat cancer treatment resistance

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Math, biology and nanotechnology are becoming strange, yet effective bed-fellows in the fight against cancer treatment resistance. Researchers at the University of Waterloo and Harvard Medical School have engineered a revolutionary new approach to cancer treatment that pits a lethal combination of drugs together into a single nanoparticle. [More]
Real-world analysis questions very low LDL targets

Real-world analysis questions very low LDL targets

Patients treated for hypercholesterolaemia in clinical practice may not derive additional benefit from very intensive statin treatment, say researchers. [More]
New protein risk score may help predict cardiovascular risk in patients with CHD

New protein risk score may help predict cardiovascular risk in patients with CHD

In a study appearing in the June 21 issue of JAMA, Peter Ganz, M.D., of the University of California-San Francisco, and colleagues conducted a study to develop and validate a score to predict risk of cardiovascular outcomes among patients with coronary heart disease using analysis of circulating proteins. [More]
People with higher levels of IgG/IgM antibodies less likely to have heart attack

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Measuring antibody levels in the blood could be used to detect a person's heart attack risk after researchers, part-funded by the British Heart Foundation, discovered that higher levels of these antibodies are linked to a lower heart attack risk. [More]
Statins can lower infection risk by 58% in stroke patients

Statins can lower infection risk by 58% in stroke patients

A Washington State University researcher has found that statin drugs can dramatically lower the risk of infections in stroke patients. [More]
Study links whole grain consumption to positive health effects

Study links whole grain consumption to positive health effects

Eating three more portions of dietary fiber a day--say, two pieces of whole grain bread and a bowl of whole grain breakfast cereal--is associated with a lower risk for all cardiovascular diseases and for dying of cancer, diabetes, and respiratory and infectious diseases, a study just published in the BMJ has shown. [More]
Prospective biobank studies with genetic data can help improve drug development, reduce costs

Prospective biobank studies with genetic data can help improve drug development, reduce costs

With drug development costs topping $1.2bn (£850 million) to get a single treatment to the point it can be sold and used in the clinic, could genetic analysis save hundreds of millions of dollars? [More]
CHD rates decrease significantly in the U.S.

CHD rates decrease significantly in the U.S.

Significant improvements seen across multiple sociodemographic groups, according to a new study in the American Journal of Preventive Medicine [More]
Weight reduction surgery improves serum lipids in obese patients

Weight reduction surgery improves serum lipids in obese patients

Fifty years after the first reported partial-ileal bypass, metabolic surgery has an established role in achieving weight loss and reducing cardiovascular death in obese patients. [More]
Liraglutide drug effectively decreases cardiovascular disease risk in type 2 diabetes patients

Liraglutide drug effectively decreases cardiovascular disease risk in type 2 diabetes patients

Researchers have shown that the glucose-lowering drug liraglutide safely and effectively decreases the overall risk of heart attack, stroke, or cardiovascular death for people with type 2 diabetes. [More]
Behavioural intervention could be effective way to improve health of RA patients

Behavioural intervention could be effective way to improve health of RA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time that a combination of text messages and individual counselling sessions to motivate patients with Rheumatoid Arthritis (RA) to be more active resulted in improved patient-reported clinical outcomes. [More]
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