Chromosome 19 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 19, one copy inherited from each parent, form one of the pairs. Chromosome 19 spans about 64 million base pairs (the building blocks of DNA) and represents more than 2 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 19 likely contains between 1,300 and 1,700 genes.

Genes on chromosome 19 are among the estimated 20,000 to 25,000 total genes in the human genome.

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.

5 Jan 2024

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models of the disease.

2 Jan 2024

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and personalized medicine by enabling the efficient delivery of biomolecules for molecular repairs and genome remodeling.

1 Jun 2023

Fiber intake associated with lower risk of cognitive decline in old people with ApoE ε4 genotype

Fiber intake is associated with a lower risk of developing cognitive decline in those old people with the Apolipoprotein E ApoE ε4 genotype, regarded as a genetic risk factor linked to the development of Alzheimer's disease.

22 Mar 2023

Age-induced methylation changes in the sperm epigenome contribute to offspring's medical problems

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Age-related methylation changes in the human sperm epigenome."

21 Mar 2023

Deep visual proteomics is redefining cancer diagnostics

In a recent study published in the journal Nature Biotechnology, researchers introduced deep visual proteomics (DVP), an amalgamation of artificial intelligence (AI) for image analysis and mass spectrometry (MS) for proteomic profiling of biological samples.

22 May 2022

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

An article published in the journal Molecular Psychiatry reveals the molecular mechanisms to explain how the YWHAZ gene –related to psychiatric and neurological disorders such as autism and schizophrenia– can alter the neurodevelopmental process.

10 May 2022

Improving our understanding of a severe pregnancy sickness (Hyperemesis Gravidarum)

News-Medical talks to Dr. Marlena Fejzo about a breakthrough in the understanding of hyperemesis gravidarum, and how it could improve maternal health around the world.

5 Apr 2022

Researchers identify distinctive biological markers for earlier detection of pregnancy risks

Researchers from Flinders University and the Robinson Research Institute at the University of Adelaide have identified distinctive biological markers that could improve the routine blood tests pregnant women already undergo and detect risks for pregnancy complications earlier than currently possible.

22 Sep 2021

Life-threatening COVID-19 associated with specific genetic variants

Results of a genome-wide association study on 2,244 critically-ill patients due to coronavirus disease (COVID-19) from 208 intensive care units across the United Kingdom revealed significant host-specific genetic determinants that can predispose people to the severe form of the disease. The report is currently available on the medRxiv preprint server.

28 Sep 2020

NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome, reveals study

An international research collaboration, including Professor IIJIMA Kazumoto et al. (of the Department of Pediatrics, Kobe University Graduate School of Medicine) has revealed that NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome in children.

3 Jul 2020

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Abnormal formation and growth of the placenta is considered an underlying cause of various pregnancy complications such as miscarriages, preeclampsia and fetal growth restriction.

25 Feb 2020

Coriell researchers find new genetic indicator of obesity risk

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person's risk for the disease.

23 Feb 2020

Faster, cheaper, better: improved gene therapy tool production

The heart of modern therapy is increasingly personalized and targeted at specific cellular or genetic deficits. This requires gene therapy, in many cases. A new study, published on 19 September 2019 in the journal Nature, describes an improved way to produce purified gene carrier viruses called AAVs cheaply and quickly, from the culture medium.

22 Sep 2019

Chromosome 19 News and Research

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Fiber intake associated with lower risk of cognitive decline in old people with ApoE ε4 genotype

Age-induced methylation changes in the sperm epigenome contribute to offspring's medical problems

Deep visual proteomics is redefining cancer diagnostics

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Improving our understanding of a severe pregnancy sickness (Hyperemesis Gravidarum)

Researchers identify distinctive biological markers for earlier detection of pregnancy risks

Life-threatening COVID-19 associated with specific genetic variants

NPHS1 is a disease-susceptibility gene for steroid-sensitive nephrotic syndrome, reveals study

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Coriell researchers find new genetic indicator of obesity risk

Faster, cheaper, better: improved gene therapy tool production

APOE gene variant may be protective and prolong life, finds study

Researchers pinpoint treatment target for rare liver cancer in adolescents, young adults

New technique may reveal clues about role of centromeres in Down syndrome, other birth defects

Lesser-known gene appears to play greater role in Alzheimer's and dementia-related memory decline

Discovery of protein that causes liver disease brings hope for new treatments

New genetic test may give men better view on how to deal with prostate cancer risk

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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