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Combining nortriptyline and morphine successfully relieves chronic neuropathic pain

Combining nortriptyline and morphine successfully relieves chronic neuropathic pain

The combination of two well-known drugs will have unprecedented effects on pain management, says new research from Queen's. [More]
Depomed acquires U.S. rights to NUCYNTA franchise from Janssen Pharmaceuticals

Depomed acquires U.S. rights to NUCYNTA franchise from Janssen Pharmaceuticals

Depomed, Inc. today announced that it has closed the acquisition of the U.S. rights to the NUCYNTA franchise from Janssen Pharmaceuticals, Inc. for $1.05 billion. The NUCYNTA franchise includes: NUCYNTA ER (tapentadol) extended release tablets indicated for the management of pain, including neuropathic pain associated with diabetic peripheral neuropathy (DPN), severe enough to require daily, around-the-clock, long-term opioid treatment; NUCYNTA (tapentadol), an immediate release version of tapentadol, for management of moderate to severe acute pain in adults; and NUCYNTA (tapentadol) oral solution, an approved oral form of tapentadol that has not been launched. [More]
Scientists use special MRI imaging to predict chronic pain, disability and PTSD after whiplash injury

Scientists use special MRI imaging to predict chronic pain, disability and PTSD after whiplash injury

While most people should expect to fully recover from whiplash injuries within the first few months, about 25 percent have long-term pain and disability that lasts many months or years. [More]
Study provides new estimates of opioid misuse, addiction

Study provides new estimates of opioid misuse, addiction

New estimates suggest that 20 to 30 percent of opioid analgesic drugs prescribed for chronic pain are misused, while the rate of opioid addiction is approximately 10 percent, reports a study in the April issue of PAIN, the official journal of the International Association for the Study of Pain. [More]
Higher levels of vitamin D decrease pain, improve function in obese patients with osteoarthritis

Higher levels of vitamin D decrease pain, improve function in obese patients with osteoarthritis

Got milk? If you are overweight and have osteoarthritis, you may want to bone up on your dairy products that have vitamin D. [More]
Clonidine Topical Gel fails to meet primary endpoint in Phase 3 study for treatment of painful diabetic neuropathy

Clonidine Topical Gel fails to meet primary endpoint in Phase 3 study for treatment of painful diabetic neuropathy

BioDelivery Sciences International, Inc. announced that the primary efficacy endpoint in the Phase 3 clinical study of Clonidine Topical Gel compared to placebo for the treatment of painful diabetic neuropathy did not meet statistical significance, although certain secondary endpoints showed statistically significant improvement over placebo. In addition, a strong safety profile for the product was observed. [More]
Top experts focus on musculoskeletal disorders in open key Congress in Milan

Top experts focus on musculoskeletal disorders in open key Congress in Milan

Musculoskeletal conditions, which affect over 1.7 billion people worldwide, will be the focus of a major four-day Congress which opens today in Milan, Italy. [More]
VIVA physician selected as new Fellows in the Society of Interventional Radiology

VIVA physician selected as new Fellows in the Society of Interventional Radiology

Dr. John D. Statler, a board-certified, fellowship-trained Interventional Radiologist with Virginia Interventional & Vascular Associates, is one of only 23 physicians nationwide selected this year as new Fellows in the Society of Interventional Radiology. [More]
Study: Early improvements not sustained in patients treated with PRP injection for facet joint arthropathy

Study: Early improvements not sustained in patients treated with PRP injection for facet joint arthropathy

Early gains in pain relief, behavioral markers and function were not sustained in patients treated with platelet-rich plasma (PRP) injection for facet joint arthropathy, new research shows. Results were available at the 31st Annual Meeting of the American Academy of Pain Medicine. [More]
Mesenchymal stem cell transplantation reduces opioid tolerance, opioid-induced pain

Mesenchymal stem cell transplantation reduces opioid tolerance, opioid-induced pain

Mesenchymal stem cell (MSC) transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research. [More]
Pain diaries may affect recovery of patients suffering from chronic pain

Pain diaries may affect recovery of patients suffering from chronic pain

For some people suffering from chronic pain, part of their daily routine is recording the extent of it in a pain diary. Often done at the request of their physician or therapist, patients may be asked to record how severe the pain is, how it affects daily activities and which treatments ease it or make it worse. [More]
AAPM announces recipients of 2015 Pain Medicine Fellowship Excellence Award

AAPM announces recipients of 2015 Pain Medicine Fellowship Excellence Award

The American Academy of Pain Medicine is pleased to announce its 2015 Pain Medicine Fellowship Excellence Award Recipients in recognition of a Pain Medicine Fellowship Program that provides an exceptional learning experience to its fellows, preparing them to deliver the highest standard of care to patients with pain. [More]
UZH researchers map spinal cord neurons involved in 'Gate Control Theory' of pain

UZH researchers map spinal cord neurons involved in 'Gate Control Theory' of pain

Sensing pain is extremely unpleasant and sometimes hard to bear - and pain can even become chronic. The perception of pain varies a lot depending on the context in which it is experienced. 50 years ago, neurobiologist Patrick Wall and psychologist Ronald Melzack formulated the so-called "Gate Control Theory" of pain. [More]
Daiichi Sankyo signs co-commercialization agreement with AstraZeneca for MOVANTIK (naloxegol)

Daiichi Sankyo signs co-commercialization agreement with AstraZeneca for MOVANTIK (naloxegol)

Daiichi Sankyo, Inc. today announced a co-commercialization agreement with AstraZeneca for MOVANTIK (naloxegol) in the US, in line with the Daiichi Sankyo strategy to expand its US portfolio through strategic alliances, in addition to internal R&D and acquisitions. [More]
Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

Anesthetics interfere with certain proteins in excitatory neurons that transmit signals

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers at Johns Hopkins Medicine have discovered that anesthetics bind to and interfere with certain proteins in excitatory neurons, which are necessary for these neurons to transmit signals involved in anesthesia and the perception of pain. [More]
Stepped-care strategy improves function, decreases pain severity in veterans

Stepped-care strategy improves function, decreases pain severity in veterans

Although U.S. military veterans who have returned from Iraq or Afghanistan are more likely to suffer chronic pain than veterans of any other conflict in American history, little headway has been made in helping them manage the often debilitating effects of chronic pain. [More]
BMC researchers to play key role in examining best treatment for acute low back pain

BMC researchers to play key role in examining best treatment for acute low back pain

Boston Medical Center researchers are part of a national clinical trial that will examine how best to treat acute low back pain and potentially prevent it from being chronic. BMC will receive $2.3 million for its role in the five-year study that was recently approved for a $14 million award by the Patient-Centered Outcomes Research Institute. [More]
83% of British people recognise that chronic pain is a serious medical condition, however only 15% receive proper treatment

83% of British people recognise that chronic pain is a serious medical condition, however only 15% receive proper treatment

Almost ten million people in the UK suffer from chronic pain, which has a major impact on quality of life and day to day activities, such as work; however many of those people do not have their pain under control or know how to go about seeking the right treatment. [More]
Accidental fentanyl exposure in children can be fatal

Accidental fentanyl exposure in children can be fatal

Infants and children are at a higher risk of accidental exposure to fentanyl patches—adhesive patches used to deliver higher doses of some opiates through the skin to relieve chronic pain. [More]
Study demonstrates that activation of cannabinoid CB2 receptors suppresses chronic pain

Study demonstrates that activation of cannabinoid CB2 receptors suppresses chronic pain

Medical marijuana is proliferating across the country due to the ability of cannabis ingestion to treat important clinical problems such as chronic pain. However, negative side effects and the development of tolerance limit the widespread therapeutic use of Δ9-tetrahydrocannabinol (Δ9-THC), the major psychoactive ingredient in cannabis. [More]
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