Malfunctioning circadian clock genes may be responsible for bipolar disorder in children. Researchers writing in the open access journal BMC Psychiatry found four versions of the regulatory gene RORB that were associated with pediatric bipolar disorder. [More]

Circadian Age, Inc. – ‘Working Nights’ – a company dedicated to helping shift workers and their families adjust to their unique lifestyles, is concerned with making sure that any health care reform will benefit the 25 million Americans working shifts. These workers represent 10% of the insured population, but incur 17% of the health care costs. [More]

If a circadian rhythm is like an orchestra - the united expression of the rhythms of millions of cells - a common chemical may serve as the conductor, or at least as the baton. [More]

Molecules that may hold the key to new ways to fight cancer and other diseases have been found to play an important role in regulating circadian rhythm, says Liheng Shi, a researcher in Texas A&M's Department of Veterinary Integrative Biosciences. [More]

Our body's activity levels fall and rise to the beat of our internal drums-the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. Whereas the master clock in the brain is set by light, the pacemakers in peripheral organs are set by food availability. The underlying molecular mechanism was unknown. [More]

Circadian Age, Inc. – ‘Working Nights’ – a company dedicated to helping shift workers and their families adjust to their unique lifestyles, is announcing a new Spanish calendar. The 2010 Working Nights Spanish Calendar offers organizations with Hispanic workers the opportunity to show added concern about the health and safety of this group of employees, by providing them with educational material in their own language, to use at home. [More]

Bob Hickman, United Feather & Down's Senior Vice Present of Sales and Marketing, and Neil A. Petrocelli, Borghese, Inc.'s Vice President of Marketing, list their top sleep and beauty tips. [More]

Chronic alcohol consumption blunts the biological clock's ability to synchronize daily activities to light, disrupts natural activity patterns and continues to affect the body's clock (circadian rhythm), even days after the drinking ends, according to a new study with hamsters. [More]

A study in the Sept.1 issue of the journal Sleep shows that the sleep-wake activity rhythms of breast cancer patients are impaired during the administration of chemotherapy. Results indicate that the first cycle of chemotherapy is associated with a temporary disruption of these rhythms, while repeated administration of chemotherapy results in progressively worse and more enduring impairments. [More]

Scientists have discovered the first gene involved in regulating the optimal length of human sleep, offering a window into a key aspect of slumber, an enigmatic phenomenon that is critical to human physical and mental health. [More]

In a new study appearing online this week in the Proceedings of the National Academy of Sciences, Dr. Liu and his co-workers have found that this mold, which uses a protein called FRQ as the main gear of its clock, marks time by a sequence of changes in the protein's chemical structure. [More]

Sleep disturbances increase as we age. Some studies report more than half of seniors 65 years of age or older suffer from chronic sleep disturbances. Researchers have long believed that the sleep disturbances common among the elderly often result from a disruption of the body's circadian rhythms - biological cycles that repeat approximately every 24 hours. [More]

Most of our cells possess an internal clock, a group of genes displaying a cyclic expression pattern that reaches a peak once a day. A large number of circadian genes are expressed by organs such as the liver, whose activity needs to be precisely regulated over the course of the day. [More]

Dartmouth Medical School geneticists have made new inroads into understanding the regulatory circuitry of the biological clock that synchronizes the ebb and flow of daily activities, according to two studies published May 15. [More]

Scientists from Queen Mary, University of London have discovered a new protein complex operating in fruit fly circadian clocks, which may also help to regulate our own biological clocks. [More]