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Cirrhosis is a condition in which the liver slowly deteriorates and malfunctions due to chronic injury. Scar tissue replaces healthy liver tissue, partially blocking the flow of blood through the liver. Scarring also impairs the liver’s ability to control infections, remove bacteria and toxins from the blood, process nutrients, hormones and drugs, make proteins that regulate blood clotting and produce bile to help absorb fats—including cholesterol—and fat-soluble vitamins.
Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists develop promising new test to identify patients with rare liver disease

Newcastle scientists and medics have developed a promising new test to identify patients with a rare liver disease who will not respond to standard treatment, allowing earlier intervention with alternatives. [More]
Over-the-counter and prescription pain medications linked to drug-induced liver injury

Over-the-counter and prescription pain medications linked to drug-induced liver injury

More than 1,000 medications, with acetaminophen being the most common, have been associated with drug-induced liver injury. [More]
Research provides insight into molecular mechanisms involved in immune response to HBV

Research provides insight into molecular mechanisms involved in immune response to HBV

The innate immune system in mammals defends against infection from viruses and other microbial infections. [More]
Women more susceptible to damaging effects of alcohol, says Houston Methodist expert

Women more susceptible to damaging effects of alcohol, says Houston Methodist expert

"One drink a day might be too much for a woman who has a genetic pre-disposition to cirrhosis of the liver," said Howard Monsour, M.D., chief of hepatology at Houston Methodist Hospital "One drink for a woman has about twice the effect as it does for the same amount consumed by a man." [More]
Low-calorie diet and exercise could improve kidney function in patients with NASH

Low-calorie diet and exercise could improve kidney function in patients with NASH

Non-alcoholic steatohepatitis (NASH) is a potentially serious liver condition characterized by excess fat in the liver associated with inflammation and scarring. [More]
Study finds way to increase liver cancer screening rates among at-risk cirrhosis patients

Study finds way to increase liver cancer screening rates among at-risk cirrhosis patients

Proactive outreach to cirrhosis patients in a safety net health system successfully doubled their screening rates for liver cancer, UT Southwestern Medical Center researchers found. [More]
Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

Hepatitis C virus sabotages antiviral defenses of liver cells by blunting effect of immune proteins

The virus that causes hepatitis C protects itself by blocking signals that call up immune defenses in liver cells, according to University of Washington researchers and colleagues reporting Nov. 14 in Nature Medicine. [More]
HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

HCV patients treated with DAA therapy not at increased risk of developing liver cancer, study finds

A new study presented this week at The Liver Meeting — held by the American Association for the Study of Liver Diseases — found patients with hepatitis C who take direct-acting antiviral medication are at no higher risk for developing liver cancer than those who do not take the medication. [More]
High-protein diets may help prevent chronic diseases by reducing liver fat

High-protein diets may help prevent chronic diseases by reducing liver fat

According to a new nutritional study conducted by the German Institute of Human Nutrition on individuals with type 2 diabetes, high-protein diets reduced liver fat by up to 48 percent within six weeks. It did not matter whether the diet was mainly based on plant or animal protein. [More]
Many Canadian territories restrict access to medications for treating hepatitis C, study finds

Many Canadian territories restrict access to medications for treating hepatitis C, study finds

A study conducted by Canadian and Australian researchers shows that nearly everywhere in Canada, the provinces and territories impose obstacles to reimbursement of new direct-acting antivirals (DAA) to treat hepatitis C by because of their cost. [More]
Japanese researchers identify mechanism for hormone that limits liver fibrosis

Japanese researchers identify mechanism for hormone that limits liver fibrosis

Nonalcoholic steatohepatitis (NASH) has been emerging worldwide and effective treatment, especially for liver fibrosis, is essential for improving the prognosis. [More]
Common drug for allergies and asthma could prevent fibrosis, reduce need for liver transplants

Common drug for allergies and asthma could prevent fibrosis, reduce need for liver transplants

A drug commonly used for the prevention of allergies and asthma someday could find new use in preventing liver disease and reducing the need for transplants, according to new research published in the October 2016 edition of the scientific journal Hepatology. [More]
Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis. [More]
New non-invasive method could improve diagnosis of severe liver disease

New non-invasive method could improve diagnosis of severe liver disease

A new non-invasive method of predicting the risk of developing a severe form of liver disease could ensure patients receive early and potentially life-saving medical intervention before irreversible damage is done. [More]
Bile acid transporter inhibitors can prevent NASH in mice, study shows

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown. [More]
UofL investigators to explore liver disease in comprehensive fashion

UofL investigators to explore liver disease in comprehensive fashion

Liver diseases are clinically important health problems and are generally underappreciated. The University of Louisville has brought together a critical mass of investigators to study liver diseases in a comprehensive fashion. [More]
Experts recommend removal of restrictions in accessing new hepatitis C therapies for drug users

Experts recommend removal of restrictions in accessing new hepatitis C therapies for drug users

Global health experts are today are calling for the removal of restrictions preventing people who use drugs from accessing new hepatitis C cures. So long as these restrictions exist, the goal of disease elimination will remain out of reach, they say. [More]
New discovery could potentially lead to treatments for Crohn's disease

New discovery could potentially lead to treatments for Crohn's disease

Scientists at the University of British Columbia have made a discovery that could potentially lead to treatments for a debilitating complication of Crohn's disease. [More]
Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals). [More]
Hydrothermal DMR results show promise in treatment of type 2 diabetes

Hydrothermal DMR results show promise in treatment of type 2 diabetes

Fractyl Laboratories Inc. (Fractyl) announced today publication of data in the current issue of Diabetes Care from the Company’s first-in-human study of RevitaTM duodenal mucosal resurfacing (Revita DMR). [More]
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