Cirrhosis is a condition in which the liver slowly deteriorates and malfunctions due to chronic injury. Scar tissue replaces healthy liver tissue, partially blocking the flow of blood through the liver. Scarring also impairs the liver’s ability to control infections, remove bacteria and toxins from the blood, process nutrients, hormones and drugs, make proteins that regulate blood clotting and produce bile to help absorb fats—including cholesterol—and fat-soluble vitamins.
The U.S. Food & Drug Administration today approved a new drug to treat people with hepatocellular carcinoma, the most common form of liver cancer.
In a new study, researchers demonstrate successful transplantation of fetal rat liver cells to an injured adult rat liver. The work is an important step toward using transplanted cells to treat liver failure, which currently requires an organ transplant.
An international study based at UT Southwestern Medical Center revealed a striking genetic-environmental interaction: Obesity significantly amplifies the effects of three gene variants that increase risk of nonalcoholic fatty liver disease by different metabolic pathways.
Patients with advanced or inoperable Hepatocellular Carcinoma (HCC) who usually received one or two treatments with liver-directed SIR-Spheres Y-90 resin microspheres in the 459-patient French SARAH study had similar survival compared to patients who received standard twice-daily systemic treatment with sorafenib, but with less than half the number and significantly fewer severe treatment-related adverse effects and significantly better Quality of Life, according to data presented here at The International Liver Congress™ 2017.
An intestinal enzyme previously shown to keep bacterial toxins from passing from the gastrointestinal system into the bloodstream may be able to prevent or reduce the liver damage caused by excess alcohol consumption.
Infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to cirrhosis as well as liver cancer. A Hepatology study from Taiwan has found that statins may provide benefits to patients with HBV- or HCV-related cirrhosis.
A unique bleeding syndrome associated with cirrhosis and portal hypertension has been identified by researchers at the Medical University of South Carolina, Wake Forest University Medical Center, and the University of Texas Southwestern Medical Center in an article published online on April 21, 2017 by the Journal of Investigative Medicine.
For some baby boomers, getting ready for a routine visit with their doctor is like training for a marathon. Some patients want to be in the best shape possible before stepping on that scale and getting those lab results.
The U.S. Food and Drug Administration today approved supplemental applications for Sovaldi (sofosbuvir) and Harvoni (ledipasvir and sofosbuvir) to treat hepatitis C virus (HCV) in children ages 12 to 17. Harvoni and Sovaldi were previously approved to treat HCV in adults.
Research led by a Houston Methodist gastroenterologist shows that patients who have inflammatory bowel disease (IBD) for more than two decades have a higher risk of developing nonalcoholic fatty liver disease (NAFLD).
Taking tissue samples from the liver to diagnose fatty liver can be replaced in most cases by a painless magnetic resonance investigation.
Researchers at University of California San Diego School of Medicine, with a cohort of clinical collaborators from across the United States, have demonstrated the impact of low and high birth weights in developing Non Alcoholic Fatty Liver Disease (NAFLD), a chronic disease that often leads to a need for organ transplantation.
Australia has the potential to eradicate hepatitis C in the next 10–15 years, according to Associate Professor Simone Strasser, gastroenterologist at Royal Prince Alfred Hospital in Sydney.
Exposure during infancy to the common plasticizer bisphenol A "hijacks" and reprograms genes in the liver of newborn rats, leading to nonalcoholic fatty liver disease in adulthood.
All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.
People who lose a partner to suicide are at increased risk for a number of mental and physical disorders, including cancer, depression, herniated discs and mood disorders than those in the general population, new Johns Hopkins Bloomberg School of Public Health research suggests.
A Brief Report appearing in the American Journal of Preventive Medicine looks at testing rates for Hepatitis C virus (HCV) two years after the United States Preventive Services Task Force recommended it for all baby boomers, and finds rates are still very low.
Recent research suggests that dietary fructose intake may increase serum uric acid concentrations and that both uric acid concentration and fructose consumption may be increased in individuals with non-alcoholic fatty liver disease.
Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is four percent or lower.
Scientists have shed new light on how the common painkiller paracetamol causes liver damage.