Cocaine Addiction News and Research

RSS

Cocaine dependence (or addiction) is physical and psychological dependency on the regular use of cocaine. It can result in severe physiological damage, psychosis, schizophrenia, lethargy, depression, or a potentially fatal overdose.

Catalyst Pharmaceutical raises $3.97 million from institutional investors

Catalyst Pharmaceutical Partners, Inc. today announced that it has closed its previously announced registered direct offering of 3.97 million shares of its common stock to institutional investors at a price per share of $1.00, representing gross proceeds of $3.97 million.

7 Oct 2009

Catalyst Pharmaceutical Partners to continue development of CPP-109 drug

Catalyst Pharmaceutical Partners, Inc. today announced that the Company will continue to develop CPP-109 (Catalyst's version of vigabatrin) for the treatment of cocaine and methamphetamine addiction.

1 Oct 2009

Computational model representing brain activity in cocaine users

About 2 million Americans currently use cocaine for its temporary side-effects of euphoria, which have contributed to making it one of the most dangerous and addictive drugs in the country. Cocaine addiction, which can cause severe biological and behavioral problems, is very difficult to overcome. Now, University of Missouri researchers Ashwin Mohan and Sandeep Pendyam, doctoral students in the Department of Electrical and Computer Engineering, are utilizing computational models to study how the brain's chemicals and synaptic mechanisms, or connections between neurons, react to cocaine addiction and what this could mean for future therapies.

23 Sep 2009

Rodents may serve as useful models to interpret parent-offspring relationships

Researchers at the Yerkes National Primate Research Center, Emory University, have demonstrated that prairie voles may be a useful model in understanding the neurochemistry of social behavior. By influencing early social experience in prairie voles, researchers hope to gain greater insight into what aspects of early social experience drive diversity in adult social behavior.

1 Sep 2009

Defendants in $10.9 million Medicare fraud HIV infusion scheme sentenced to 63 months in prison

Miami physician Keith Russell, 65, and physician's assistant Jorge Luis Pacheco, 50, were each sentenced to 97 months in prison, and physician's assistant Eda Marietta Milanes, 43, was sentenced to 63 months in prison, for their roles in fraud schemes that involved billing Medicare for $10,903,509 worth of unnecessary HIV infusion treatments, Assistant Attorney General Lanny A. Breuer of the Criminal Division; Acting U.S. Attorney Jeffrey H. Sloman of the Southern District of Florida; and Daniel R. Levinson, Inspector General of the Department of Health & Human Services (HHS) announced today.

9 Aug 2009

Novel approach for developing an AIDS vaccine

Researchers at the Yerkes National Primate Research Center, Emory University, believe conventional vaccine strategies should not be the only avenue explored in the development of an effective AIDS vaccine.

7 Aug 2009

Adolescent cocaine use in Northern Ireland

Research conducted by the Institute of Child Care Research at Queen's School of Sociology, Social Policy and Social Work has found that 7.5% of young people who took part in the Belfast Youth Development Survey had tried cocaine at least once by the age of 16.

30 Jun 2009

Cocaine and heroin increase permeability of the placenta

Cocaine and heroin increase permeability of the placenta. Researchers writing in BioMed Central's open access journal Reproductive Biology and Endocrinology have shown that exposure to the drugs causes an increase in the passage of some chemicals into the fetus.

10 Jun 2009

Catalyst Pharmaceutical Partners announces top-line results of CPP-109 phase II trial for cocaine addiction

Catalyst Pharmaceutical Partners, Inc. has announced top-line results from its U.S. Phase II clinical trial to treat cocaine addiction.

31 May 2009

Impaired ability to monitor behavior, emotions may underlie vulnerability to drugs; suggests new targets for treatment

Parts of the brain involved in monitoring behaviors and emotions show different levels of activity in cocaine users relative to non-drug users, even when both groups perform equally well on a psychological test.

25 May 2009

A new path for cocaine addiction research

Cocaine is one of the oldest drugs known to humans, and its abuse has become widespread since the end of the 19th century. At the same time, we know rather little about its effects on the human brain or the mechanisms that lead to cocaine addiction.

19 May 2009

Research shows how cocaine regulates gene expression in a crucial reward region

The study, published by Cell Press in the May 14th issue of the journal Neuron, provides exciting insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction.

13 May 2009

Promising new targets for medications to treat cocaine addiction

Repeated use of addictive drugs such as cocaine causes long-lasting changes in parts of the brain involved in motivation and reward, among others, yet the precise mechanisms by which these changes are maintained are poorly understood.

13 May 2009

Scientists use eye tracking to detect mild dementia in humans

Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans.

15 Apr 2009

Blocking hunger hormone helps fight cocaine addiction

UC Irvine pharmacological researchers have discovered that blocking a hormone related to hunger regulation can limit cocaine cravings.

1 Apr 2009

Recent drug use masks cocaine abusers' cognitive impairment

Recent cocaine use may hide some of the cognitive deficits commonly experienced by individuals addicted to cocaine, scientists at the U.S. Department of Energy's Brookhaven National Laboratory report in a study published in the April 2009 issue of Neuropsychopharmacology - a special issue dedicated to cocaine research.

3 Mar 2009

Researchers discover gene variation linked to cocaine addiction and cocaine-induced paranoia

Researchers from Boston University School of Medicine (BUSM) and Yale University School of Medicine and the University of Connecticut School of Medicine, have discovered that variants in the á-endomannosidase (MANEA) gene are associated with cocaine addiction and cocaine-induced paranoia in European American and African American populations.

2 Mar 2009

Drug-related preference in cocaine addiction extends to images

When given a choice between viewing pictures of cocaine and a variety of other images, cocaine addicted individuals, as compared to healthy, non-addicted research subjects, show a clear preference for the drug-related images.

16 Nov 2008

Study sheds light on why addiction is a chronic disease

Drug addiction dramatically shifts a person's attention, priorities, and behaviors towards a focus almost entirely on seeking out and taking drugs. Now, an animal study funded by the National Institute on Drug Abuse, part of the National Institutes of Health, has identified some of the specific long-term adaptations in the brain's reward system that may contribute to this shift.

31 Jul 2008

Molecular fingerprint of cocaine addiction revealed

The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the amount and activity of various proteins affecting brain function.

27 May 2008