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Study identifies conditions required to further develop liver and pancreas cells

Study identifies conditions required to further develop liver and pancreas cells

AMSBIO reports on the recent publication in Nature Protocols1 by Dr Meritxell Huch** and co-workers which describes development of culture conditions that allow the long-term expansion of adult primary tissues from the liver and pancreas into self-assembling 3D organoid cultures. [More]
IQWiG finds both hint of benefit and harm from corneal collagen cross-linking for keratoconus

IQWiG finds both hint of benefit and harm from corneal collagen cross-linking for keratoconus

In patients with keratoconus the cornea of the eye begins to bulge. So-called corneal collagen cross-linking aims to halt this process. In this procedure, the cornea is stiffened through locally applied vitamin B2 in combination with UVA radiation. [More]
MGH researchers develop new methods for mapping and measuring solid stress in tumors

MGH researchers develop new methods for mapping and measuring solid stress in tumors

Massachusetts General Hospital investigators have developed new methods for mapping and measuring solid stress - the force exerted by solid and elastic components - within tumors, an accomplishment that may lead to improved understanding of those forces and their consequences and to novel treatment strategies. [More]

RIT scientists to explore properties of vitreous gel to find clues for vision disorders

Research is underway at Rochester Institute of Technology that will give scientists a better understanding of the vitreous humor, or gel, that fills the eye and could lead to advances in the treatment of vision disorders, drug delivery and eye surgery. [More]
Pitt researcher finds way to regenerate heart tissues in mammals

Pitt researcher finds way to regenerate heart tissues in mammals

Many lower forms of life on earth exhibit an extraordinary ability to regenerate tissue, limbs, and even organs--a skill that is lost among humans and other mammals. [More]
Nature article highlights use of QGel's designer matrices for intestinal and colorectal cancer organoid culture

Nature article highlights use of QGel's designer matrices for intestinal and colorectal cancer organoid culture

Nature, the leading weekly international scientific journal, yesterday reported the first intestinal and colorectal cancer organoid culture in fully defined extra cellular matrices (ECM). [More]
Promethera presents new preclinical NASH-Fibrosis data from HepaStem program at AASLD meeting

Promethera presents new preclinical NASH-Fibrosis data from HepaStem program at AASLD meeting

Promethera Biosciences SA, a world-leading cell therapy and regenerative medicine company targeting liver diseases, today announced the presentation of new preclinical NASH-Fibrosis data from its proprietary HepaStem program, demonstrating a beneficial effect of HepaStem in a nonalcoholic steatohepatitis (NASH) mouse model and confirming Hepastem’s unique and multifaceted mode of action. [More]
Lonza’s RAFT 3D Cell Culture System helps researchers develop corneal models for research into blindness treatment

Lonza’s RAFT 3D Cell Culture System helps researchers develop corneal models for research into blindness treatment

Lonza’s RAFT 3D Cell Culture System has been used to develop corneal models for research into treatment for a painful and potentially blinding corneal disease. [More]
BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

For the first time, researchers have shown that using Magnetic Resonance Imaging (MRI) can effectively identify bone marrow cancer (myelofibrosis) in an experimental model. [More]
New study identifies novel target for treatment of Graves' disease and other scarring eye conditions

New study identifies novel target for treatment of Graves' disease and other scarring eye conditions

A new class of therapies may be on the horizon for thyroid eye disease (TED) and other destructive scarring conditions. [More]
Aortic rigidity in African-Americans linked to excess risk of hypertension and cardiovascular disease

Aortic rigidity in African-Americans linked to excess risk of hypertension and cardiovascular disease

African-Americans have more rigidity of the aorta, the major artery supplying oxygen-rich blood to the body, than Caucasians and Hispanics, according to a study by UT Southwestern Medical Center cardiologists. [More]
Six pioneering French companies to exhibit in innovation zone at Medica 2016

Six pioneering French companies to exhibit in innovation zone at Medica 2016

In a global market worth almost €200 billion (around £173 billion) a year, the medical devices and in vitro diagnostics sector is particularly innovative in France. Across the Channel, the sector is comprised of over a thousand companies, employing almost 65,000 people with expertise encompassing medicine, mechanics, material physics and digital technologies. [More]
Pitt-led researchers awarded NIH grant to improve risk assessment of cerebral aneurysms

Pitt-led researchers awarded NIH grant to improve risk assessment of cerebral aneurysms

Although cerebral aneurysms affect a substantial portion of the adult population, the risk of treatment including open brain surgery often outweighs the risks associated with rupture. [More]
New scaffold could improve outcome of periodontal regenerative surgery

New scaffold could improve outcome of periodontal regenerative surgery

A new regenerative scaffold made of biosafe collagen hydrogel and collagensponge could possess the ability of retaining fibroblastic growth factor-2 (FGF2) and stimulate the periodontal tissue regeneration, according to new research published in The Open Dentistry Journal. [More]
Swiss specialists report success of new cell-based repair technology for articular cartilage defects

Swiss specialists report success of new cell-based repair technology for articular cartilage defects

Writing in The Lancet, Swiss doctors report that cartilage cells harvested from patients’ own noses have been used to successfully produce cartilage transplants for the treatment of the knees of 10 adults (aged 18-55 years) whose cartilage was damaged by injury. [More]
Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer. [More]
Innovative procedure may improve outcomes in people with keratoconus

Innovative procedure may improve outcomes in people with keratoconus

An innovative procedure may improve outcomes in people with a degenerative eye disease, suggest five-year results from a study presented at AAO 2016, the 120th annual meeting of the American Academy of Ophthalmology. [More]
Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis. [More]
New review shows both types of diabetes increase risk of fragility fractures

New review shows both types of diabetes increase risk of fragility fractures

Recent research has shown that bone health is compromised in people with diabetes, resulting in a significantly higher risk of fragility fracture. [More]
Biomedical engineers develop artificial blood vessels capable of growth within recipient

Biomedical engineers develop artificial blood vessels capable of growth within recipient

In a groundbreaking new study led by University of Minnesota biomedical engineers, artificial blood vessels bioengineered in the lab and implanted in young lambs are capable of growth within the recipient. [More]
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