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Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year. According to the American Cancer Society, colon cancer is the third leading cause of cancer-related death in the U.S., accounting for about 10 percent of all cancer deaths.
Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth. [More]
New ESMO guidelines reflect personalized approach for management of metastatic colorectal cancer

New ESMO guidelines reflect personalized approach for management of metastatic colorectal cancer

ESMO, the leading European professional organisation for medical oncology, has released new consensus guidelines for the management of metastatic colorectal cancer that reflect an increasingly personalized approach to treatment, as published online today in Annals of Oncology. [More]
Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Genetic test detects colon cancer-linked DNA in blood to predict disease recurrence risk

Scientists at the Johns Hopkins Kimmel Cancer Center and University of Melbourne report they have used a genetic test that spots bits of cancer-related DNA circulating in the blood to accurately predict the likelihood of the disease's return in some — but not all — of a small group of patients with early-stage colon cancer. [More]
TAILOR study shows treatment with Erbitux plus FOLFOX improves survival in RAS wild-type mCRC patients

TAILOR study shows treatment with Erbitux plus FOLFOX improves survival in RAS wild-type mCRC patients

Merck, a leading science and technology company, will present data at the ESMO 18th World Congress on Gastrointestinal Cancer from the pivotal Phase III TAILOR study in patients from China, the first prospective trial to evaluate an anti-EGFR antibody in the first-line therapy of patients with RAS wild-type metastatic colorectal cancer (mCRC). [More]
Enzyme from fermented Japanese vegetable boosts colon health in rats

Enzyme from fermented Japanese vegetable boosts colon health in rats

An enzyme produced by fermenting a vegetable common in Japanese cuisine may be responsible for increasing the amount of at least one beneficial bacterium associated with healthy colons in a study using rats. [More]
Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Venuprasad Poojary, PhD, an associate investigator at Baylor Institute for Immunology Research (BIIR), part of Baylor Scott & White Research Institute, reported this week in the journal Nature Immunology the role of a key protein in the regulatory pathway that is involved in limiting colon inflammation and tumor growth. [More]
Researchers develop new computational method to track colorectal cancer progression

Researchers develop new computational method to track colorectal cancer progression

Team of researchers elaborated a computational method to track the progress of the colorectal cancer. It is a scientific advance that can bring new perspectives to discover the factors that push this pathology and the selection of efficient therapies. [More]
Primary care visits lead to more screenings and follow-up colonoscopies

Primary care visits lead to more screenings and follow-up colonoscopies

People who visit their primary care physicians are more likely to get potentially life-saving colon cancer screenings and follow up on abnormal stool blood test results - even in health systems that heavily promote mail-in home stool blood tests that don't require a doctor visit, a study involving UT Southwestern population health researchers shows. [More]
Siemens Healthineers' new CT and MRI technologies to aid research across various common clinical pathways

Siemens Healthineers' new CT and MRI technologies to aid research across various common clinical pathways

The Transforming Outcomes and Health Economics Through Imaging (TOHETI) programme is looking to change the way medical imaging works by undertaking a range of pioneering research. [More]
Study sheds new light on how overeating may lead to more eating

Study sheds new light on how overeating may lead to more eating

Research is finally beginning to shed light on some of the reasons that extra weight is difficult to shed permanently. Now, a new study has uncovered another method by which the gut senses how much food a person eats and relays that to the brain. [More]
Insurance coverage of CT colonography and other USPSTF-recognized tests could help fight CRC

Insurance coverage of CT colonography and other USPSTF-recognized tests could help fight CRC

Final United States Preventive Services Task Force (USPSTF) colorectal cancer screening recommendations assigned an "A" grade to colorectal cancer (CRC) screening in those ages 50-75 years and provided a list of recognized screening exams. [More]
Aspirin may increase likelihood of surviving colon cancer

Aspirin may increase likelihood of surviving colon cancer

It is well known that the drug ASA, also known internationally as Aspirin, has analgesic and fever-reducing properties. However, this drug may also increase the likelihood of surviving colon cancer. [More]
Personlized exercise pattern may help reduce neuropathic symptoms of chemotherapy

Personlized exercise pattern may help reduce neuropathic symptoms of chemotherapy

Researchers at the University of Rochester Wilmot Cancer Institute discovered something simple and inexpensive to reduce neuropathy in hands and feet due to chemotherapy--exercise. [More]
Eating walnuts may offer protection against colon tumors

Eating walnuts may offer protection against colon tumors

Eating walnuts may change gut bacteria in a way that suppresses colon cancer, researchers led by UConn Health report in the journal Cancer Prevention Research. [More]
Interventions for breast cancer patients show benefits based on women’s stress levels

Interventions for breast cancer patients show benefits based on women’s stress levels

Is a couples' support group or an enhanced couples' group therapy intervention with skill instruction more effective for helping women diagnosed with early stage breast cancer? According to research from an investigator at Rutgers Cancer Institute of New Jersey and colleagues from other facilities across the country, neither intervention is more dominant, but each has its own benefits depending on the stress level of the patient. [More]
Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

For uninsured patients who are at a high risk for colorectal cancer (CRC), performing free screening colonoscopies can identify cancer at an earlier stage and appears to be cost neutral from a hospital system perspective, according to study results published online in the Journal of the American College of Surgeons ahead of print publication. [More]
Nutrition, safety tips for grilling season

Nutrition, safety tips for grilling season

Cooking meat, including beef, pork, fish, or poultry, with high-temperature methods such as pan frying or grilling directly over an open flame can increase exposure to chemicals that can cause changes in DNA that may increase the risk of cancer, according to the National Cancer Institute. [More]
Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells. [More]
Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

A team of researchers from Cornell University in Ithaca, New York demonstrated a drug delivery mechanism that utilizes two independent vehicles, allowing for delivery of chemically and physically dis-tinct agents. [More]
Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today. [More]
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