Colorectal Cancer News and Research RSS Feed - Colorectal Cancer News and Research

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.
NEJM publishes MINDACT trial results

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy. [More]
Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. [More]
U-M study casts doubt on possible link between obesity and imbalance of microbes

U-M study casts doubt on possible link between obesity and imbalance of microbes

For people with weight problems, news headlines in recent years may have brought relief, as researchers studying the microscopic creatures inside our bodies reported possible links between obesity and an out-of-whack balance of microbes. [More]
Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals). [More]
Colorectal tumors present epigenetic heterogeneity, study finds

Colorectal tumors present epigenetic heterogeneity, study finds

A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program of Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at University of Barcelona discovers that colorectal tumors present epigenetic heterogeneity that relates to the clinical course of the disease. [More]
Study shows microRNA molecule prevents cancer cells from responding to chemotherapy treatment

Study shows microRNA molecule prevents cancer cells from responding to chemotherapy treatment

Annually about 2000 Danish patients with colorectal cancer are treated with chemotherapy. Today, a range of different chemotherapeutic regimens are available. However, deciding which regimen to use is not easy. [More]
Greater screening can help improve colorectal cancer rates among Hispanic men in California

Greater screening can help improve colorectal cancer rates among Hispanic men in California

Colorectal cancer incidence and mortality rates in California have decreased markedly for men and women in all major racial-ethnic groups since 1990, except for Hispanic men. [More]
Study finds high rates of increasing obesity in patients with history of cancer

Study finds high rates of increasing obesity in patients with history of cancer

A study at Columbia University's Mailman School of Public Health showed that obesity was more prevalent in patients with a history of cancer than in the general population, and survivors of colorectal and breast cancers were particularly affected. [More]
Early and late menopause linked to increased risk of developing type 2 diabetes

Early and late menopause linked to increased risk of developing type 2 diabetes

Women who begin menopause before age 46 or after 55 have an increased risk of developing type 2 diabetes, according to a study of more than 124,000 women enrolled in the Women's Health Initiative, a large national trial aimed at preventing disease in postmenopausal women. [More]
Adhesive patch can deliver triple combination therapy to tumor sites

Adhesive patch can deliver triple combination therapy to tumor sites

Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in the U.S. In Europe, it is the second-most common form of cancer. [More]
Blood cancer is associated with considerably higher healthcare costs than other cancers

Blood cancer is associated with considerably higher healthcare costs than other cancers

Health economics studies, published today in The Lancet Haematology, report that the cost of treating blood cancers is twice that for treating other cancers. This is largely because they require more complex treatment regimens that necessitate longer hospital stays. [More]
Bowel Cancer UK conducts two free Colorectal Cancer Study Days for healthcare professionals

Bowel Cancer UK conducts two free Colorectal Cancer Study Days for healthcare professionals

The UK’s leading bowel cancer research charity, Bowel Cancer UK, is holding two Colorectal Cancer Study Days, to provide healthcare professionals with an essential update in prevention, screening, early detection and treatment of colorectal cancer. [More]
Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States. [More]
NorthShore launches first clinical trial to examine GRS test for cancer risk assessment

NorthShore launches first clinical trial to examine GRS test for cancer risk assessment

Researchers at NorthShore University HealthSystem have launched the first clinical trial to investigate a genetic risk score (GRS) test to predict the risk of breast, prostate and colorectal cancer in the primary care setting. [More]
Research shows biglycan molecule plays key role in determining tumour malignancy

Research shows biglycan molecule plays key role in determining tumour malignancy

Researchers at Hokkaido University in Japan have demonstrated that a molecule, called biglycan, plays an intrinsic role in attracting tumour cells toward the inner wall of tumour blood vessels. [More]
Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structures. [More]
Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Expanding the potential of existing cancer therapies: an interview with Dr Mark Rutstein

Cancer remains a leading cause of death worldwide, and the global cancer burden is expected to increase by 70 percent over the next two decades. [More]
Recellularized colon model helps identify cancer driver genes involved in CRC progression

Recellularized colon model helps identify cancer driver genes involved in CRC progression

Genetic mutations are a major cause of cancer, and tracking the role of each gene in cancer pathogenesis has long been an important tool in the fight against a disease that is expected to kill more than 1.6 million people this year. [More]
Research opens up new ways to detect, inhibit cancer spread

Research opens up new ways to detect, inhibit cancer spread

Clusters of circulating cells commonly found in the blood of cancer patients have long been the subject of research on cancer. These clusters have been regarded for more than 50 years as malignant cells that have broken off from the primary tumor, spreading cancer to other parts of the body. [More]
Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence

Ludwig researchers working in collaboration with colleagues in Australia and the US have shown that fragments of tumor DNA circulating in the blood can be used to gauge the risk of colorectal cancer recurrence and the efficacy of chemotherapy following surgery. [More]
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