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Colorectal Cancer News and Research RSS Feed - Colorectal Cancer News and Research

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

New studies suggest elevated risk of gastrointestinal cancers in diabetic patients

20. November 2009 02:27
There are minimal data assessing the relationship between diabetes with gallbladder, biliary and pancreatic cancer. Recent small studies have suggested an elevated risk of pancreatic cancer only in patients with diabetes mellitus (DM). [More]

Comprehensive report on world cancer therapies market

20. November 2009 01:37
Research and Markets (http://www.researchandmarkets.com/research/4b82d8/cancer_therapies) has announced the addition of the "Cancer Therapies - Global Market Opportunities" report to their offering. [More]

Gastrointestinal symptoms may interfere with nutritional management of ED patients

20. November 2009 00:08
Eating disorders (ED) patients display a high prevalence of gastrointestinal symptoms and functional gastrointestinal disorders such as irritable bowel syndrome. These symptoms may interfere with their nutritional management. Ingestion of fructose-sorbitol (F-S) is an established means of gastrointestinal symptom provocation in irritable bowel syndrome patients. [More]

Embryonic stem cells raise hope of cellular replacement therapy for liver failure

19. November 2009 07:32
Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. There have been several protocols available for hepatic fate specification from ES cells, however, most of the protocols currently used result in low yield or purity of functional hepatocytes. Valproic acid (VPA), a histone deacetylase inhibitor, has been demonstrated to facilitate the hepatic differentiation of mesenchymal stem cells. However, little is know about whether VPA could induce the hepatic differentiation of ES cells. [More]

Recent progress of Delcath Systems in drug delivery platform reported

19. November 2009 07:16
Delcath Systems, Inc., a medical technology company developing the Delcath Percutaneous Hepatic Perfusion (PHP(TM)) System, a minimally invasive drug delivery platform for the regional treatment of cancer metastatic to the liver, today reported on the Company's recent progress. [More]

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Report on unexplained liver haemorrhage after metastasis radiofrequency ablation published

19. November 2009 05:42
Colorectal carcinoma is one of the most common cancers in the world. Approximately one in four of these patients have metastases at diagnosis, liver being the most common site involved. Although historically it was considered that liver metastases meant a very poor prognosis, today, due to improved systemic therapy, many patients will be candidates for local hepatic treatments such as surgery or less aggressive radiofrequency ablation. [More]

Reduction of serum bilirubin, the hallmark of successful biliary drainage

19. November 2009 04:09
Biliary drainage is performed as a palliative treatment of hilar cholangiocarcinoma. The reduction of serum bilirubin is usually the hallmark of successful biliary drainage. However, some patients may have persistent jaundice or scanty bile output after biliary drainage. [More]

Study: EP4 agonist may reduce gastric bleeding and inflammation

19. November 2009 03:46
Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding. [More]

Experimental study shows beneficial effects of Vardenafil on NSAID-induced gastric ulcer

19. November 2009 00:54
Indomethacin has been proved by epidemiological and experimental studies to be closely associated with peptic ulcer development. Vardenafil is a potent phosphodiesterase 5 inhibitor and its effects on the gastric mucosa havenot been reported. [More]

Interim data from an ongoing phase 1 dose-escalation trial of XL147 reported

19. November 2009 00:22
Exelixis, Inc. today reported interim data from an ongoing phase 1 dose-escalation trial of XL147 (SAR245408) in combination with the EGFR inhibitor erlotinib in patients with advanced solid tumors. [More]

Green tea prevents the development of hepatic fibrosis in rat model of DMN-induced liver fibrosis

18. November 2009 10:24
Several studies have shown that lipid peroxidation stimulates collagen production in fibroblasts and hepatic stellate cells (HSC), and plays an important role in the development of liver fibrosis. Hepatoprotective effects of green tea against carbon tetrachloride, cholestasis and alcohol induced liver fibrosis were reported in many studies. However, the hepatoprotective effect of green tea in dimethylnitrosamine (DMN)-induced models has not been studied. [More]

Lee's Pharmaceutical granted exclusive license to Jennerex' lead product for HCC

18. November 2009 09:34
Jennerex, Inc., a clinical-stage biotherapeutics company developing a proprietary breakthrough class of targeted oncolytic virus therapeutics, today announced in conjunction with Lee's Pharmaceutical Holdings, the execution of a collaboration and license agreement for Jennerex's lead product candidate, JX-594, in certain Asian territories. [More]

Enzo Biochem to market GeneNews’ ColonSentry in New York and New Jersey

18. November 2009 07:42
Enzo Biochem, Inc. (NYSE:ENZ) today announced that it has entered into an agreement with GeneNews (TSX: GEN), of Toronto, Canada, for exclusive rights to market GeneNews’ ColonSentry™, a proprietary blood test for colorectal cancer, in the states of New York and New Jersey. [More]

Updated clinical data from Poniard Pharmaceuticals' picoplatin Phase 2 trial announced

18. November 2009 04:36
Poniard Pharmaceuticals, Inc. today announced updated clinical data from its randomized, controlled Phase 2 trial of picoplatin in patients with metastatic colorectal cancer (CRC). [More]

Study examines link between folic acid and cancer incidence

18. November 2009 03:40
Patients with heart disease in Norway, a country with no fortification of foods with folic acid, had an associated increased risk of cancer and death from any cause if they had received treatment with folic acid and vitamin B12, according to a study in the November 18 issue of JAMA. [More]
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