Colorectal Cancer

Colorectal Cancer is cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus). In the United States, it is the fourth most common cancer in men and women. Caught early, it is often curable.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Colorectal Cancer Pathogenesis

Microbial Dysbiosis and Colorectal Cancer

Colorectal Cancer and Organ Preservation

Latest Colorectal Cancer News and Research

Roasted green tea boosts mental task performance, study finds

Study examines how the consumption of green tea and roasted green tea affects human responses during mental tasks, demonstrating that roasted green tea can enhance performance and reduce fatigue.

15 Apr 2024

New cancer projections show increased prostate cases by 25% in 2050, despite prevention efforts

The reduction in prevalence that could be accomplished by rigorously applying all known preventive measures against cancer.

15 Apr 2024

Linking lifestyle to longevity: How diet and hypertension sway risks for heart disease and cancer

Study reviews epidemiological evidence linking modifiable risk factors like diet and hypertension to both cardiovascular disease (CVD) and cancer, suggesting a shared pathophysiology and potential strategies for simultaneous prevention and management.

11 Apr 2024

Study provides reassurance regarding the safety of using hormone therapy after age 65 years

After the Women's Health Initiative (WHI) in 2002, many women have resisted taking hormone therapy (HT), especially after age 65 years, because of fears of increased risks for various cancers and heart disease.

10 Apr 2024

Deciphering cancer plasticity:Insights from MSK research

About 90% of deaths from cancer are a result of metastasis -; that is, from cancer's ability to spread from an initial primary tumor to seed new tumors throughout the body, often in the lungs, liver, and brain.

10 Apr 2024

New protein-based micromaterials developed for targeted cancer therapy

Researchers at the Universitat Autònoma de Barcelona (UAB), in collaboration with the Sant Pau Research Institute and the CIBER-BBN, have developed micromaterials made up only of proteins, capable of delivering over an extended period of time nanoparticles that attack specific cancer cells and destroy them.

5 Apr 2024

Study identifies microbiota signatures associated with KRAS mutations in colorectal cancer patients

For about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those mutations have been linked to shorter survival and more aggressive forms of disease.

4 Apr 2024

The whey to go: Researchers unlock the potential of whey-derived proteins for cancer prevention

The current evidence regarding the significance of whey protein for cancer prevention and treatment.

4 Apr 2024

Tuberculosis linked to increased risk of cancer, study finds

A population-wide observational study to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows an association between tuberculosis (TB) and cancer, with those with current or previous TB more likely to have a diagnosis of a variety of cancers, including lung, blood, gynaecological and colorectal cancers.

1 Apr 2024

Drug combination could hold new promise for treating colorectal cancers and other solid tumors

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published today in Science Advances.

27 Mar 2024

Review explains lesser-known yet vital components of the Mediterranean diet

A comprehensive overview of the Mediterranean diet's underappreciated components, revealing new dietary factors beyond the well-studied fruits, vegetables, and olive oil, including eggs, dairy, nuts, seeds, herbs, spices, and red wine, to better define and benefit from this diet.

25 Mar 2024

COVID-19 pandemic considerably disrupted colorectal cancer surgery, study shows

While the COVID-19 pandemic is no longer considered a public health emergency, pandemic-related stressors continue to impact cancer care across the board.

25 Mar 2024

MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

25 Mar 2024

Enhanced screening could significantly decrease cervical cancer cases and deaths

Getting screened for cervical cancer isn't fun. And getting an alert that your initial exam showed a potential sign of trouble, and that you need to go back for a test or procedure to rule out cancer, is even less fun.

20 Mar 2024

Researchers discover link between FBXW7 mutations and EGFR signaling in colorectal cancer

The Organoid group at the Hubrecht Institute have identified a new link between FBXW7 mutations and EGFR signaling activity.

18 Mar 2024

Study shows AI tool's high accuracy in answering genetic counseling questions

An artificial intelligence tool correctly answered 83 percent of common genetic counseling questions, including those about genetic testing and genetic syndromes, a new study found.

18 Mar 2024

Non-invasive blood test shows 83% sensitivity in detecting colorectal cancer, offering hope for early diagnosis

The performance of a blood-based testing method that uses cell-free deoxyribonucleic acid (DNA) to screen for colorectal cancer.

18 Mar 2024

Ultra-processed foods: The new silent killer

From fizzy drinks to cereals and packaged snacks to processed meat, ultra-processed foods are packed with additives.

14 Mar 2024

ACS urges people to be on the lookout for five potential warning signs of colorectal cancer

In the recent Cancer Facts & Figures 2024 report from the American Cancer Society (ACS), researchers revealed a stark increase in colorectal cancer (CRC) incidence among Americans under the age of 55.

14 Mar 2024

Blood test shows 83% accuracy in detecting colorectal cancer

A blood test intended for screening for colorectal cancer in people who are of average risk and not experiencing symptoms correctly detected colorectal cancer in 83% of people confirmed to have the disease, according to a study published March 14 in the New England Journal of Medicine.

13 Mar 2024