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Constipation is a condition in which stool becomes hard, dry, and difficult to pass, and bowel movements don’t happen very often. Other symptoms may include painful bowel movements, and feeling bloated, uncomfortable, and sluggish.
Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

A naturally-occurring compound has been found to block a molecular process thought to underlie Parkinson's Disease, and to suppress its toxic products, scientists have reported. [More]
Mediplus develops new silicone pessaries that eliminate clinical risks associated with surgical mesh

Mediplus develops new silicone pessaries that eliminate clinical risks associated with surgical mesh

Women who suffer from incontinence or pelvic organ prolapse from obesity, heavy lifting, smoking, chronic constipation or childbirth don’t always need surgery according to a pioneering British medical device manufacturer. [More]
Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers identify new biological target for treating spinal muscular atrophy

Johns Hopkins researchers along with academic and drug industry investigators say they have identified a new biological target for treating spinal muscular atrophy. [More]
Women with IBS experience worse quality of life than men, new research shows

Women with IBS experience worse quality of life than men, new research shows

Double work and a high embarrassment factor can lead to the quality of life being affected more among women than men by irritable bowel syndrome (IBS), a very common gastrointestinal disease. [More]
Ardelyx initiates two clinical trials to evaluate new treatment for hyperkalemia

Ardelyx initiates two clinical trials to evaluate new treatment for hyperkalemia

Ardelyx, Inc., a clinical-stage company focused on enhancing the treatment of patients with gastrointestinal and cardiorenal diseases, today announced the initiation of a Phase 3 clinical trial and an onset-of-action clinical trial evaluating RDX7675 in patients with hyperkalemia, a potentially life-threatening condition common in patients with cardiorenal disease. [More]
Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration has approved SPINRAZATM (nusinersen) under Priority Review for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients. [More]
FDA approves first drug to treat children and adults with spinal muscular atrophy

FDA approves first drug to treat children and adults with spinal muscular atrophy

The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement. [More]
FDA awards accelerated approval to new ovarian cancer drug

FDA awards accelerated approval to new ovarian cancer drug

The U.S. Food and Drug Administration today granted accelerated approval to Rubraca (rucaparib) to treat women with a certain type of ovarian cancer. [More]
Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine. [More]
New study shows link between defective sucrase-isomaltase gene variants and IBS

New study shows link between defective sucrase-isomaltase gene variants and IBS

Irritable bowel syndrome (IBS) affects a large portion of the general population. New research coordinated by Karolinska Institutet now shows a link between defective sucrase-isomaltase gene variants and IBS. [More]
Tips and tricks to get children through pains of teething

Tips and tricks to get children through pains of teething

Your baby is growing up so fast. It seems like just yesterday you were welcoming them home, listening to their first coos and, unfortunately, getting used to some sleepless nights. [More]
Identifying foods that trigger IBS: an interview with Dr Bill Chey

Identifying foods that trigger IBS: an interview with Dr Bill Chey

IBS is a common medical condition which is diagnosed in the presence of characteristic gastrointestinal symptoms including recurring bouts of abdominal pain and diarrhea and/or constipation. IBS patients also commonly report bloating and abdominal distension or swelling. [More]
Diagnosis and management of constipation may help protect kidney health

Diagnosis and management of constipation may help protect kidney health

Researchers have discovered a link between constipation and poor kidney health. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, suggest that the diagnosis and management of constipation might be helpful for preventing or treating kidney disease. [More]
Many back pain patients taking opioids get limited relief and worry about side effects, study finds

Many back pain patients taking opioids get limited relief and worry about side effects, study finds

Millions of people take opioids for chronic back pain, but many of them get limited relief while experiencing side effects and worrying about the stigma associated with taking them, suggests research presented at the ANESTHESIOLOGY 2016 annual meeting. [More]
Clinical study reveals safety and efficacy of novel investigational colonoscopy prep

Clinical study reveals safety and efficacy of novel investigational colonoscopy prep

Detailed results from a Phase 2 study of a novel colonoscopy prep (ECP) under development by ColonaryConcepts, LLC show the investigational treatment to be at least as effective and safe as two currently available colonoscopy prep formulations, while offering a much higher level of patient satisfaction and preference than standard preps. [More]
Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

Patients with hypothyroidism have nagging symptoms despite normal TSH tests, medication use

About 15 percent of the 10-12 million people in the U.S. with hypothyroidism, or an underactive thyroid, continue to feel sick despite following the standard of care recommended by the American Thyroid Association. [More]
Alternative therapies appear to be effective in ameliorating IBS symptoms

Alternative therapies appear to be effective in ameliorating IBS symptoms

A new review looks at the evidence behind the effectiveness of complementary or alternative therapies-including probiotics, prebiotics, synbiotics, fiber, and herbal medicinal products-for the treatment of bowel disorders such as irritable bowel syndrome (IBS), functional constipation, and ulcerative colitis. [More]
FDA recommends consumers to stop using homeopathic teething tablets and gels

FDA recommends consumers to stop using homeopathic teething tablets and gels

The U.S. Food and Drug Administration is warning consumers that homeopathic teething tablets and gels may pose a risk to infants and children. The FDA recommends that consumers stop using these products and dispose of any in their possession. [More]
Headache disorders may increase risk of thyroid condition

Headache disorders may increase risk of thyroid condition

Sufferers of migraines, cluster headaches, tension headaches or other headache disorders are at greater risk of developing a thyroid condition called hypothyroidism, according to a study by University of Cincinnati College of Medicine researchers. [More]
Bile acid transporter inhibitors can prevent NASH in mice, study shows

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown. [More]
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