Coronary Artery Disease News and Research RSS Feed - Coronary Artery Disease News and Research

Coronary artery disease is the most common type of heart disease and the leading cause of death worldwide. It occurs when the arteries that supply blood to the heart become narrowed or blocked by a buildup of "plaque" - cholesterol or other fatty deposits that build on the inner wall of the artery. Over time, this plaque build up results in a reduction of blood flow to the heart, which can cause chest pain. If the artery becomes completely blocked, usually by a blood clot, oxygen is prevented from reaching the heart which can result in a heart attack and/or damage to the heart tissue.
FDA approves CryoLife's next generation HeRO device

FDA approves CryoLife's next generation HeRO device

CryoLife, Inc., a leading tissue processing and medical device company focused on cardiac and vascular surgery, announced today that it has received U.S. Food and Drug Administration 510(k) clearance for a next generation HeRO (Hemodialysis Reliable Outflow) device. [More]
Weight loss and heart damage: an interview with Dr Lili Barouch, Johns Hopkins University School of Medicine

Weight loss and heart damage: an interview with Dr Lili Barouch, Johns Hopkins University School of Medicine

Obesity causes an increase in the stiffness of the heart, making it hard for the heart muscle to relax and fill with blood in between heartbeats. This abnormal stiffness can lead to congestive heart failure and other problems as it becomes more severe. [More]
Integrated advanced cardiovascular imaging modalities can change cardiac care

Integrated advanced cardiovascular imaging modalities can change cardiac care

Focusing on problem solving clinical approach, places the emphasis firmly on identifying the best test to answer each specific question in the most efficient way. [More]
POZEN announces submission of NDA for marketing approval of PA32540/PA8140

POZEN announces submission of NDA for marketing approval of PA32540/PA8140

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, today announced the submission of a New Drug Application to the U.S. Food and Drug Administration for the marketing approval of PA32540/PA8140. [More]

Pregnancy-associated plasma protein A predicts cardiovascular events: Study

Higher levels of pregnancy-associated plasma protein A were associated with an increased risk of cardiovascular events in people with cardiac chest pain that developed as a result of heart disease/coronary artery disease, according to a study published in CMAJ. [More]
New insights on differences in cardiovascular pathophysiology between women and men

New insights on differences in cardiovascular pathophysiology between women and men

Groundbreaking new insights on the differences in cardiovascular pathophysiology between women and men will be presented by Marianne Legato, MD, a globally recognized expert in gender specific medicine, and consultant to the Women's Heart Foundation in her keynote address at the 98th Annual American Medical Women's Association Conference in New York City, on March 15-17, 2013. [More]
ASTRONAUT trial finds no beneficial effects of aliskiren in recently hospitalized heart failure patients

ASTRONAUT trial finds no beneficial effects of aliskiren in recently hospitalized heart failure patients

Despite high hopes that a blood pressure-lowering medication called aliskiren would help people following hospitalization for heart failure, no beneficial effects were found, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session. [More]
DKCRUSH-III trial results show differences in technically challenging bifurcation lesions

DKCRUSH-III trial results show differences in technically challenging bifurcation lesions

Patients with a type of coronary lesion linked with poor prognosis fared significantly better with the stent technique known as double kissing crush than with culotte stenting, according to data from the DKCRUSH-III trial presented today at the American College of Cardiology's 62nd Annual Scientific Session. [More]
Trial evaluates ranolazine in patients with diabetes, coronary artery disease and angina

Trial evaluates ranolazine in patients with diabetes, coronary artery disease and angina

A commonly used anti-anginal drug reduces chest pain in patients with type 2 diabetes and appears to have a more pronounced effect in those with poorer glucose control, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session. [More]

Women with atrial fibrilation have more symptoms and lower quality of life than men

Women with atrial fibrilation have more symptoms and lower quality of life than men with the same heart condition, according to an analysis of patients in a large national registry compiled by the Duke Clinical Research Institute. [More]

Cangrelor more effective than clopidogrel in preventing blood clots

A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent procedures. [More]
Addition of niacin to statin does not improve HDL function

Addition of niacin to statin does not improve HDL function

While two large clinical trials recently showed that adding niacin to statin therapy failed to improve clinical outcomes despite a significant increase in HDL-C levels, little is known about exactly why the increased HDL-C levels did not reduce the risk of cardiovascular events, including heart attack and stroke. [More]

Abbott announces data from MitraClip system study on mitral regurgitation

Abbott today announced data from the EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy) High Surgical Risk cohort evaluating the company's first-in-class catheter-based MitraClip System for the treatment of mitral regurgitation (MR). [More]
Cardiac rehab program may reduce death rate in women with coronary artery disease

Cardiac rehab program may reduce death rate in women with coronary artery disease

Women with coronary artery disease who completed a 12-week cardiac rehabilitation program were two-thirds less likely to die compared to those who were not referred to the program. [More]

Failure to use aspirin before angioplasty increases death rate

Despite recommendations from leading medical groups, a surprising number of patients are not given aspirin before artery-clearing coronary angioplasty and stenting, and those patients have a significantly higher in-hospital death rate, according to research from a Michigan network being presented at the American College of Cardiology's 62nd Annual Scientific Session. [More]
Patients with PTSD more likely to develop insulin resistance, metabolic syndrome and heart disease

Patients with PTSD more likely to develop insulin resistance, metabolic syndrome and heart disease

Patients diagnosed with post-traumatic stress disorder (PTSD) have a significantly higher risk of developing insulin resistance and metabolic syndrome, placing them at greater risk for heart disease and diabetes, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. Researchers say public health interventions are urgently needed to prevent PTSD-related metabolic disorder at its early, reversible stage. [More]
Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Even minor weight loss is associated with worse health outcomes among patients implanted with a certain type of defibrillator known as cardiac resynchronization therapy with defibrillator (CRT-D), according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. [More]
New Orleans residents continue to face increased risk of heart attack post-Katrina

New Orleans residents continue to face increased risk of heart attack post-Katrina

New Orleans residents continue to face a three-fold increased risk of heart attack post-Katrina-a trend that has remained unchanged since the storm hit in 2005, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. [More]
Study evaluates patients with regional myocardial wall thinning

Study evaluates patients with regional myocardial wall thinning

Among patients with coronary artery disease referred for cardiovascular magnetic resonance and found to have regional myocardial wall thinning (of the heart muscle), limited scar burden was associated with improved contraction of the heart and reversal of wall thinning after revascularization, suggesting that myocardial thinning is potentially reversible, according to a study appearing in the March 6 issue of JAMA. [More]
Endocrine Society issues position statement on estradiol measurement

Endocrine Society issues position statement on estradiol measurement

In a Position Statement unveiled today, The Endocrine Society advocates that all methods for measuring estrogens, which play a crucial role in human biology, be made traceable to a common standard. [More]