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Single-step fermentative method may facilitate industrial-scale statin drug production

Single-step fermentative method may facilitate industrial-scale statin drug production

University of Manchester researchers, together with industrial partner DSM, have developed a single-step fermentative method for the production of leading cholesterol-lowering drug, pravastatin, which will facilitate industrial-scale statin drug production. [More]
New research finds that synthetic flame retardants can cause metabolic and liver problems

New research finds that synthetic flame retardants can cause metabolic and liver problems

Chemicals used as synthetic flame retardants that are found in common household items such as couches, carpet padding, and electronics have been found to cause metabolic and liver problems that can lead to insulin resistance, which is a major cause of obesity, according to new research from the University of New Hampshire. [More]
Vanderbilt's Stacey Kendrick suggests nine simple steps for healthier heart

Vanderbilt's Stacey Kendrick suggests nine simple steps for healthier heart

In observance of Heart Month in February, Vanderbilt health educator Stacey Kendrick has compiled a list of steps everyone can take for a healthier heart. [More]
Blood pressure-lowering treatment lowers CVD, heart disease risks among type 2 diabetes patients

Blood pressure-lowering treatment lowers CVD, heart disease risks among type 2 diabetes patients

Blood pressure-lowering treatment among patients with type 2 diabetes is associated with a lower risk of cardiovascular disease (CVD) and heart disease events and improved mortality, according to a study in the February 10 issue of JAMA. [More]
Cardiologist promotes the importance of controlling high blood pressure

Cardiologist promotes the importance of controlling high blood pressure

During Heart Month, the Cardiovascular Institute of New Jersey at Rutgers Robert Wood Johnson Medical School is promoting the importance of controlling high blood pressure, also called hypertension, in order to reduce the risk of coronary heart disease and other related chronic disorders in adults. [More]
Twitter can indicate community's psychological well being, predict rates of heart disease

Twitter can indicate community's psychological well being, predict rates of heart disease

Twitter has broken news stories, launched and ended careers, started social movements and toppled governments, all by being an easy, direct and immediate way for people to share what's on their minds. Researchers from the University of Pennsylvania have now shown that the social media platform has another use: Twitter can serve as a dashboard indicator of a community's psychological well being and can predict rates of heart disease. [More]
Regular outdoor walking in groups boosts health, reduces life-threatening conditions

Regular outdoor walking in groups boosts health, reduces life-threatening conditions

Risk of stroke, coronary heart disease, depression and other life-threatening conditions can be reduced through regular outdoor walking in groups, according to research from the University of East Anglia. [More]
Cold 'sensor' hold key to new therapeutic target for treatment of frostbite and hypothermia

Cold 'sensor' hold key to new therapeutic target for treatment of frostbite and hypothermia

A cold 'sensor' which triggers the skin's vascular response to the cold could represent an exciting new therapeutic target for the treatment of frostbite and hypothermia, according to scientists at King's College London. [More]
Disease-associated malnutrition imposes economic burden on society

Disease-associated malnutrition imposes economic burden on society

Even in food-abundant industrialized countries like the U.S., an alarming number of people, particularly seniors, are in a state of diseased-associated malnutrition. Because of the impact on patient health, disease-associated malnutrition imposes a significant economic burden on society of $157 billion per year, according to new research published in a supplemental issue of the Journal of Parenteral and Enteral Nutrition and supported by Abbott. [More]
Researchers uncover easily detectable, 'pre-malignant' state in the blood

Researchers uncover easily detectable, 'pre-malignant' state in the blood

Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and Harvard-affiliated hospitals have uncovered an easily detectable, "pre-malignant" state in the blood that significantly increases the likelihood that an individual will go on to develop blood cancers such as leukemia, lymphoma, or myelodysplastic syndrome. [More]
Presence of certain proteins in HDL can lead to cardiovascular risk

Presence of certain proteins in HDL can lead to cardiovascular risk

A current study by the MedUni Vienna has shown that changes to the "good cholesterol" HDL (High-Density Lipoprotein) can be associated with cardiovascular diseases: by developing a new laboratory test, scientists at the Institute of Medical Genetics and the Department of Nephrology & Dialysis (University Department of Internal Medicine III) at the MedUni Vienna have demonstrated for the first time that the presence of certain proteins in the HDL can lead to an increased risk of cardiovascular disease and mortality. [More]
Changes in one gene can influence person's cholesterol levels from midlife through late life

Changes in one gene can influence person's cholesterol levels from midlife through late life

It's known that cholesterol levels typically rise as people age and that high cholesterol levels are associated with increased risk of cardiovascular disease. What's less known is that cholesterol levels begin to decline the more a person ages. Recently, researchers from the University of Texas Medical Branch at Galveston and the University of Kentucky found that differences in one gene can influence a person's cholesterol levels from midlife to late life. [More]
Scientists identify defects in colossal heart protein which leads to stroke, heart failure

Scientists identify defects in colossal heart protein which leads to stroke, heart failure

The landmark discovery of a tiny defect in a vital heart protein has for the first time enabled heart specialists to accurately pinpoint a therapeutic target for future efforts in developing a drug-based cure for cardiovascular diseases. [More]
A single gene mutation can halve the risk of heart disease

A single gene mutation can halve the risk of heart disease

Recent research has shown that inactivation of a single gene reduces the risk of heart attack by 50%. [More]
Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare mutations that shut down a single gene are linked to lower cholesterol levels and a 50 percent reduction in the risk of heart attack, according to new research from Washington University School of Medicine in St. Louis, the Broad Institute at Massachusetts Institute of Technology and Harvard, and other institutions. [More]
FDA accepts Amgen's evolocumab BLA for review

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol. [More]
Moderate alcohol consumption can protect against coronary heart disease, but only for some people

Moderate alcohol consumption can protect against coronary heart disease, but only for some people

A new study at Sahlgrenska Academy, University of Gothenburg, confirms that moderate alcohol consumption can protect against coronary heart disease. [More]
Oats play important role in human health

Oats play important role in human health

According to a new, wide-reaching collection of scientific reviews published in the October 2014 supplement issue of the British Journal of Nutrition, oats may play an important role in improving satiety, diet quality and digestive, cardiovascular and general metabolic health. [More]
Study: Certain prostate cancer medications linked to cardiac death risk

Study: Certain prostate cancer medications linked to cardiac death risk

A new study has found that certain prostate cancer medications are linked with an increased risk of dying from heart-related causes in men with congestive heart failure or prior heart attacks. Published in BJU International, the findings will help doctors and patients weigh the benefits and risks of the drugs. [More]
Dietary linoleic acid lowers risk of coronary heart disease

Dietary linoleic acid lowers risk of coronary heart disease

People who swap 5% of the calories they consume from saturated fat sources such as red meat and butter with foods containing linoleic acid—the main polyunsaturated fat found in vegetable oil, nuts, and seeds—lowered their risk of coronary heart disease (CHD) events by 9% and their risk of death from CHD by 13%, according to a new study led by Harvard School of Public Health researchers. [More]