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New brain pathway links reward and learning centers

New findings published in the journal Nature Neuroscience have shed light on a mysterious pathway between the reward center of the brain that is key to how we form habits, known as the basal ganglia, and another anatomically distinct region where nearly three-quarters of the brain's neurons reside and assist in motor learning, known as the cerebellum.

25 Jan 2024

New technique helps track the brain's "off switches"

For decades, scientists have studied the intricate activity patterns in human and animal brains by observing when different groups of brain cells turn on.

23 Jan 2024

Thinning brain tissue predicts dementia up to a decade before symptoms

A ribbon of brain tissue called cortical gray matter grows thinner in people who go on to develop dementia, and this appears to be an accurate biomarker of the disease five to 10 years before symptoms appear, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported.

22 Jan 2024

Study provides new insights into aging process of the human mind

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has demonstrated that communication among memory-coding neurons - nerve cells in the brain responsible for maintaining working memory - is disrupted with aging and that this can begin in middle age.

22 Jan 2024

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

Researchers performed a randomized clinical trial to compare resting-state functional magnetic resonance imaging connectivity-guided intermittent theta burst stimulation vs. repetitive transcranial magnetic stimulation for therapy-resistant depression.

19 Jan 2024

MIT study reveals consistent oscillation patterns across brain cortex layers

Throughout the brain's cortex, neurons are arranged in six distinctive layers, which can be readily seen with a microscope.

18 Jan 2024

Unlocking the anti-inflammatory secrets of bergamot byproducts

The positive effect of bergamot derivatives.

17 Jan 2024

Revolutionary transparent graphene microelectrodes enhance brain imaging and stimulation

The decoding of single-cell and average neural activities from surface potentials.

15 Jan 2024

FDA-approved drug may help to decrease pain after surgery, study finds

Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.

12 Jan 2024

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the blood for easy detection.

12 Jan 2024

Revolutionary blood test monitors gene expression dynamics in the brain

The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels.

11 Jan 2024

Research reveals COVID-19's lasting impact on brain function and structure

Study investigates post-COVID-19 cognitive defects, finding that SARS-CoV-2 infections are linked to brain injury markers and reduced cingulate cortex volume, with corticosteroids offering some cognitive protection.

10 Jan 2024

Nicotine beliefs elicit dose-response reactions in human brains

Researchers investigate whether nicotine-related beliefs may influence brain processes in a dose-dependent manner similar to pharmaceutical effects.

10 Jan 2024

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Researchers developed an advanced prime editor-engineered virus-like particle (PE-eVLP) system, significantly enhancing gene editing efficiency in human cells and showing potential for treating genetic diseases.

9 Jan 2024

Study opens doors for more effective OCD treatment based on individual brain profiles

Marking a substantial advancement in understanding OCD, researchers from Zhejiang University School of Medicine have revealed key connections between clinical characteristics, neuroimaging and treatment, heralding new opportunities for improved diagnostic and therapeutic strategies.

9 Jan 2024

Photobiomodulation alleviates Aβ deposition and cognitive decline in mice with Alzheimer’s disease

Alzheimer's disease (AD) is an age-related neurodegenerative disorder. β-amyloid (Aβ) deposition in the brain is a crucial contributor to the pathogenesis of AD, mitigating excessive cerebral Aβ burden has been considered as a possible therapeutic strategy for AD.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Does being physically fit improve your attention span?

Better physical fitness is associated with better attention and concentration.

8 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

How deeply someone can be hypnotized -; known as hypnotizability -; appears to be a stable trait that changes little throughout adulthood, much like personality and IQ.

4 Jan 2024

Cortex News and Research

New brain pathway links reward and learning centers

New technique helps track the brain's "off switches"

Thinning brain tissue predicts dementia up to a decade before symptoms

Study provides new insights into aging process of the human mind

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

MIT study reveals consistent oscillation patterns across brain cortex layers

Unlocking the anti-inflammatory secrets of bergamot byproducts

Revolutionary transparent graphene microelectrodes enhance brain imaging and stimulation

FDA-approved drug may help to decrease pain after surgery, study finds

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

Revolutionary blood test monitors gene expression dynamics in the brain

Research reveals COVID-19's lasting impact on brain function and structure

Nicotine beliefs elicit dose-response reactions in human brains

Breakthrough in gene editing: Enhanced virus-like particles promise new era in genetic disease treatment

Study opens doors for more effective OCD treatment based on individual brain profiles

Photobiomodulation alleviates Aβ deposition and cognitive decline in mice with Alzheimer’s disease

Engineered virus-like particles power up gene editing, correcting blindness in mice

Does being physically fit improve your attention span?

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Stanford Medicine researchers demonstrate new way to temporarily heighten hypnotizablity

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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