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CorMedix submits IND application to FDA for Neutrolin

CorMedix submits IND application to FDA for Neutrolin

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiac, renal and infectious disease, is pleased to announce that an Investigational New Drug application (IND) for Neutrolin was submitted to the United States Food and Drug Administration on Wednesday, September 24, 2014. [More]
RDT receives FDA clearance for Tempus Pro advanced medical monitor

RDT receives FDA clearance for Tempus Pro advanced medical monitor

RDT is pleased to announce that, following CE and other market approvals, it has received 510k clearance by the US Food and Drug Administration for the addition to the Tempus Pro medical monitor of: 12 Lead ECG recording interpretation, real-time arrhythmia detection, ST and QT monitoring and alarming (unique to a fully-featured pre-hospital transport monitor) an additional two channels of invasive blood pressure (four in total), Masimo rainbow SET co-oximetry, video laryngoscope and ultrasound. [More]
MediValve successfully completes post-market clinical evaluation of acWire Guidewire

MediValve successfully completes post-market clinical evaluation of acWire Guidewire

MediValve, Ltd., a Trendlines portfolio company, today announced that it has successfully completed the first two cases of post-market clinical evaluation of its acWire Guidewire. [More]
New evidence-based guidelines for prevention, treatment of POAF

New evidence-based guidelines for prevention, treatment of POAF

The American Association for Thoracic Surgery has released new evidence-based guidelines for the prevention and treatment of perioperative and postoperative atrial fibrillation (POAF) and flutter for thoracic surgical procedures. [More]
Yale University researchers study potential new treatment to reverse effects of pulmonary fibrosis

Yale University researchers study potential new treatment to reverse effects of pulmonary fibrosis

Yale University researchers are studying a potential new treatment that reverses the effects of pulmonary fibrosis, a respiratory disease in which scars develop in the lungs and severely hamper breathing. [More]
Avalon Ventures, GSK jointly launch two new early-stage life science companies

Avalon Ventures, GSK jointly launch two new early-stage life science companies

Avalon Ventures today announced the launch of two new companies formed through its collaboration with GlaxoSmithKline to fund and launch up to 10 early-stage life science companies. [More]
Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

Researchers at UT-Southwestern Medical Center have found that the most common variant of the circulating protein apolipoprotein E, called apoE3, helps repair the lining of blood vessels. Individuals with another variant, called apoE4, do not get the benefit of this repair, putting them at higher risk for cardiovascular disease. [More]

Medicone Medical Response selected as one of fastest growing companies in the US

MedicOne Medical Response, a leading provider emergency and non-emergency ambulance transport services, has been selected by Inc. Magazine as one of the fastest growing private companies in America. [More]
Instrumentation Laboratory announces launch of HemosIL Direct Thrombin Inhibitor Assay in Europe

Instrumentation Laboratory announces launch of HemosIL Direct Thrombin Inhibitor Assay in Europe

Instrumentation Laboratory today announced the commercialization in Europe of their HemosIL Direct Thrombin Inhibitor (DTI) Assay. When used in conjunction with HemosIL Dabigatran Calibrators and Controls, this test offers an automated solution for the measurement of dabigatran, a direct oral anticoagulant (DOAC). [More]
Study: High-dose prescribing increases by 23% in Canada

Study: High-dose prescribing increases by 23% in Canada

High-dose opioid prescribing increased by 23 per cent in Canada between 2006 and 2011, despite clinical guidelines recommending that most patients should avoid high-doses of these drugs, according to new research. [More]
Peer pressure influences adherence to hand hygiene

Peer pressure influences adherence to hand hygiene

Nationally, hand hygiene adherence by healthcare workers remains staggeringly low despite its critical importance in infection control. [More]
Most prevalent form of discrimination is due to mental illness and homelessness

Most prevalent form of discrimination is due to mental illness and homelessness

Vulnerable populations in ethnically diverse Toronto reported more discrimination by health care workers based on their housing status, mental health or substance abuse issues than race, a new study has found. [More]
Treatment with xenon gas after head injury reduces extent of brain damage

Treatment with xenon gas after head injury reduces extent of brain damage

Treatment with xenon gas after a head injury reduces the extent of brain damage, according to a study in mice. [More]
New potential therapeutic targets for treatment of pulmonary arterial hypertension

New potential therapeutic targets for treatment of pulmonary arterial hypertension

Two new potential therapeutic targets for the treatment of pulmonary arterial hypertension, a deadly disease marked by high blood pressure in the lungs, have been identified by researchers at the University of Illinois at Chicago. [More]
Sepsis patients more likely to survive when treated at hospital with higher volume of cases

Sepsis patients more likely to survive when treated at hospital with higher volume of cases

Patients with sepsis, one of the most time-sensitive and hard-to-detect illnesses in medicine, are more likely to survive the life-threatening condition when treated at a hospital that sees a higher volume of sepsis cases. [More]
New paper highlights ways to improve outcomes of Ebola virus infection

New paper highlights ways to improve outcomes of Ebola virus infection

The largest-ever Ebola virus disease outbreak is ravaging West Africa, but with more personnel, basic monitoring, and supportive treatment, many of the sickest patients with Ebola virus disease do not need to die, note the authors of a new paper published ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. [More]
Research roundup: Benefits of hip surgery; preventing surgical infections; assessing ACOs' predecessors

Research roundup: Benefits of hip surgery; preventing surgical infections; assessing ACOs' predecessors

Surgical treatment of hip fractures can achieve better survival and functional outcomes than nonoperative treatment, but less is known about its economic benefits. ... We estimated the effects of surgical treatment for displaced hip fractures through a Markov cohort analysis of patients 65 years and older. ... Estimated average lifetime societal benefits per patient exceeded the direct medical costs of hip fracture surgery by $65,000 to $68,000 for displaced hip fractures. With the exception of the assumption of nursing home use, the sensitivity analyses show that surgery produces positive net societal savings (Gu, Koenig, Mather and Tongue, 8/5). [More]
CHLA ECMO program honored with prestigious Award for Excellence in Life Support

CHLA ECMO program honored with prestigious Award for Excellence in Life Support

The Extracorporeal Membrane Oxygenation program at Children's Hospital Los Angeles has been honored for the third time with the prestigious Award for Excellence in Life Support by the Extracorporeal Life Support Organization, an international group of health care professionals and scientists who evaluate hospital treatment therapies for patients fighting complex cardiac disease and respiratory failure. [More]
International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

International consortium to accelerate collaborative multi-site trials of potential Ebola vaccine

A candidate Ebola vaccine could be given to healthy volunteers in the UK, The Gambia and Mali as early as September, as part of an series of safety trials of potential vaccines aimed at preventing the disease that has killed more than 1,400 people in the current outbreak in West Africa. [More]
New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

Oxidized lipids are known to play a key role in inflaming blood vessels and hardening arteries, which causes diseases like atherosclerosis. A new study at UCLA demonstrates that they may also contribute to pulmonary hypertension, a serious lung disease that narrows the small blood vessels in the lungs. [More]