Crohn's Disease News and Research RSS Feed - Crohn's Disease News and Research

Crohn’s disease is a chronic inflammatory disease of the bowel affecting at least 115,000 people in the UK. The condition usually develops in teenagers and young adults, but can be diagnosed at any age and is equally common in men and women.

The condition can affect any part of the digestive tract between the mouth and the anus, although inflammation in the last section of the small bowel (ileum) or the first part of the large bowel (colon) is most common.

Crohn's disease is a ‘relapsing and remitting’ condition characterized by symptom-free periods followed by episodes of “flare-ups,” during which symptoms such as diarrhoea, abdominal pain, fever and fatigue may become particularly bothersome.

Long term, severe inflammation can damage sections of the digestive system, resulting in additional complications, such as a tear in the wall of the anus (fissure), narrowing of the intestine (stricture) or the formation of an abnormal connection between the bowel and another body part such as the bladder, vagina or skin (fistula). Such problems usually require surgical treatment to correct. Crohn's disease also increases the risk of developing bowel cancer.

The exact cause of Crohn's disease is not clear but experts believe a combination of factors may be at work including genetics, immune responses to certain bacteria or viruses and lifestyle factors such as diet or smoking status.
New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

New review provides insights on rates, predictors of relapse after surgery in Crohn's disease patients

Some patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition and many patients relapse after surgery. [More]
Cornell researchers develop chemical probe activated by UV light to control inflammation

Cornell researchers develop chemical probe activated by UV light to control inflammation

Black light does more than make posters glow. Cornell researchers have developed a chemical tool to control inflammation that is activated by ultraviolet (UV) light. [More]
Early life history and genetics may play crucial role in shaping gut microbiome

Early life history and genetics may play crucial role in shaping gut microbiome

Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28. in the journal Nature Microbiology. [More]
DNA changes in blood samples could pave way for simple tests to diagnose IBD

DNA changes in blood samples could pave way for simple tests to diagnose IBD

Scientists have identified chemical changes in the DNA of patients with inflammatory bowel diseases that could improve screening for the conditions. [More]
New research shows immune paralysis in sepsis patients can be reversed

New research shows immune paralysis in sepsis patients can be reversed

Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar. [More]
Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease. [More]
FDA approves new assay for diagnosis of IBD

FDA approves new assay for diagnosis of IBD

Inova Diagnostics, a worldwide leader in autoimmune diagnostic reagents and systems for the clinical laboratory, is pleased to announce the US Food and Drug Administration clearance of QUANTA Lite Calprotectin Extended Range, an assay which aids in the diagnosis of Inflammatory Bowel Disease (IBD), and can help differentiate IBD from Irritable Bowel Syndrome (IBS). [More]
CannaCure Florida offers medical cannabis educational conference following legalization of marijuana

CannaCure Florida offers medical cannabis educational conference following legalization of marijuana

CannaCure Florida is proudly offering the most comprehensive medical cannabis educational conference following passage of Florida Amendment 2 legalizing medical marijuana. [More]
Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study. [More]
Researchers create new culture model of human intestine to study inflammatory bowel disease

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk. [More]
Many ulcerative colitis patients with anemia do not receive testing and treatment, study reports

Many ulcerative colitis patients with anemia do not receive testing and treatment, study reports

Many patients with ulcerative colitis don't receive recommended testing and treatment for the common problem of iron deficiency anemia, reports a study in the October issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Wolters Kluwer. [More]
Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit The Cell Factory in collaboration with Women's and Children's Health Department of the University of Padua and the Padua University Hospital are developing therapies for inflammatory bowel disease (IBD) using extracellular vesicles (EVs). [More]
Researchers identify genomic regions linked to ulcerative colitis in African-Americans

Researchers identify genomic regions linked to ulcerative colitis in African-Americans

In the first genome-wide association study of genetic risk factors for inflammatory bowel disease in African Americans, a research team has identified two regions of the genome (loci) associated with ulcerative colitis only in people of African descent. [More]
IBD diagnosis in childhood does not affect educational achievements and lifestyle, study finds

IBD diagnosis in childhood does not affect educational achievements and lifestyle, study finds

Twenty-five percent of inflammatory bowel disease (IBD) patients are diagnosed as children or adolescents -- at the peak of their social and educational development. [More]
Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some cases of depression, concludes a review led by the University of Cambridge, which further implicates our immune system in mental health disorders. [More]
Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Scientists at the National Institutes of Health and Emory University have experimentally induced sustained remission of SIV, the simian form of HIV, in infected monkeys. [More]
Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient's quality of life and is notoriously hard to treat successfully, in part because its course and severity vary so much from one case to the next. [More]
Common food-poisoning bacteria linked to increased risk of Crohn's disease

Common food-poisoning bacteria linked to increased risk of Crohn's disease

People who retain a particular bacterium in their gut after a bout of food poisoning may be at an increased risk of developing Crohn's disease later in life, according to a new study led by researchers at McMaster University. [More]
Researchers to investigate similarities between Crohn's and Johne's disease that affects cattle

Researchers to investigate similarities between Crohn's and Johne's disease that affects cattle

Researchers still have a lot to learn about Crohn's disease, a chronic form of inflammatory bowel disorder that affects as many as 700,000 Americans. [More]
Scientists reveal molecular elements that bridge anxiety and metabolism

Scientists reveal molecular elements that bridge anxiety and metabolism

Metabolic and anxiety-related disorders both pose a significant healthcare burden, and are in the spotlight of contemporary research and therapeutic efforts. Although intuitively we assume that these two phenomena overlap, the link has not been proven scientifically. [More]
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