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Rare variants in the YKT6 gene cause new neurological disorder, study finds

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

1 Apr 2024

Research highlights health risks posed by 2,6-DHNPs in drinking water

2,6-DHNPs, a group of disinfection byproducts (DBPs), are raising alarm bells for public health. These bad actors in the water world are tougher and more toxic than many other pollutants, making it hard for typical water cleaning methods to get rid of them.

29 Mar 2024

Revolutionizing cysteine-rich peptide production for drug discovery

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.

22 Mar 2024

Unlocking quinoa's power: Beyond nutrition to drug development

Existing data on the bioactive constituents of quinoa and their health benefits.

18 Mar 2024

Black garlic may have anti-cancer and anti-inflammatory properties

The anti-inflammatory and anti-cancer properties of black garlic (BG).

5 Feb 2024

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Over 700 million people were infected and almost seven million died, making SARS-CoV-2 the most devastating pandemic of the 21st century.

25 Jan 2024

Natural compounds show promise in modulating heme breakdown, offering new therapeutic avenues

Study explores the impact of natural compounds on bilirubin production and heme catabolic pathway modulation, highlighting their potential in treating neurodegenerative and cardiovascular diseases.

3 Jan 2024

Deciphering how amino acids control cell growth and autophagy in yeast

Amino acids are the building blocks of life. We obtain them from the food we eat, and the body uses them to make proteins, which in turn are used for growth, development, and a multitude of other functions.

21 Dec 2023

New insights into the structures formed during antibody aggregation through 3D domain swapping

Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development.

8 Dec 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

The effectiveness of herbs and alternative medicines in preventing liver injury induced by anti-tuberculosis (anti-TB) drugs.

16 Nov 2023

Moringa-infused gluten-free sourdough offers health boost for all, especially celiacs

Researchers have developed a gluten-free sourdough bread fortified with Moringa oleifera, an unconventional crop known for its health benefits. The study found that this novel bread formulation offers enhanced nutritional content, including higher levels of protein and essential minerals, making it a viable option for people with celiac disease and those seeking healthier bread alternatives.

30 Oct 2023

Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Is hemp the superfood vegetarians have been waiting for?

This recent study in the journal Nutrients delves into the nutritional power of hemp seeds, highlighting their potential as a rich source of proteins, essential fatty acids, and dietary fiber—particularly valuable for vegetarians. The paper also suggests that hemp could offer numerous health benefits, from antioxidant activity to potentially aiding in metabolic and cardiovascular diseases, paving the way for more focused research.

22 Sep 2023

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

AlphaMissense, an adaptation of AlphaFold, offers a highly accurate model for predicting the pathogenicity of human proteome-wide missense variants at the single amino acid level. The model outperforms existing methods, providing valuable insights for diagnosing rare diseases and developing targeted therapies.

20 Sep 2023

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Researchers explore the distinguishing features of MIS-C as compared to other inflammatory-infectious syndromes in children.

4 Aug 2023