Cytokines News and Research RSS Feed - Cytokines News and Research

Cytokine is a substance that is made by cells of the immune system. Some cytokines can boost the immune response and others can suppress it. Cytokines can also be made in the laboratory by recombinant DNA technology and used in the treatment of various diseases, including cancer.
New research identifies key enzyme linked to age-related increases in cancer and inflammation

New research identifies key enzyme linked to age-related increases in cancer and inflammation

For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania. [More]
Research: Adenosine deaminase may help activate immune system against HIV

Research: Adenosine deaminase may help activate immune system against HIV

New research findings published in the February 2016 issue of the Journal of Leukocyte Biology, suggest that a new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug. [More]
Research points to potential use of radiotherapy in treating systemic cancer

Research points to potential use of radiotherapy in treating systemic cancer

An international team of researchers lead by the University of Granada has proven that mesenchymal stem cells (MSC) may be used as enhancer agents of local and systemic effects of radiotherapy, that is to say, those which affect the irradiated tumour and tumour cells located at a certain distance of the irradiated ones. [More]
Certain viral infections during pregnancy could cause behavioral changes in offspring

Certain viral infections during pregnancy could cause behavioral changes in offspring

A study published in the journal Science found that activation in pregnant mice of a particular immune response, similar to what may occur with certain viral infections during pregnancy, alters the brain structure of the mouse offspring and causes behavioral changes, reminiscent of those observed in humans with autism spectrum disorder (ASD). [More]
UAB discovery may offer new therapeutic approaches to asthma

UAB discovery may offer new therapeutic approaches to asthma

University of Alabama at Birmingham researchers have found a previously unknown step in the pathway that leads to asthma, a discovery that may offer new therapeutic approaches to this incurable disease. Asthma affects more than 25 million people in the United States, including about 7 million children. [More]
Study identifies potential therapeutic targets for treatment of multiple sclerosis

Study identifies potential therapeutic targets for treatment of multiple sclerosis

Treatment of multiple sclerosis (MS) and other inflammatory diseases may benefit by new findings from a study that identified potential therapeutic targets for a devastating disease striking some 2.3 million people worldwide. [More]
Shire announces resubmission of lifitegrast NDA to FDA for treatment of dry eye disease in adults

Shire announces resubmission of lifitegrast NDA to FDA for treatment of dry eye disease in adults

Shire plc today announced it has resubmitted the New Drug Application (NDA) to the U.S. Food and Drug Administration for its investigational candidate, lifitegrast, for the treatment of signs and symptoms of dry eye disease in adults. Shire resubmitted the NDA in response to the complete response letter (CRL) the company received from the FDA on October 16, 2015. [More]
Researchers use ASC secreted factors to create therapeutic factor concentrate for critical limb ischemia

Researchers use ASC secreted factors to create therapeutic factor concentrate for critical limb ischemia

"Critical limb ischemia" (CLI) describes an advanced stage of peripheral artery disease characterized by obstruction of the arteries and a markedly reduced blood flow to the extremities. CLI identifies patients at high-risk for major amputation. The estimated annual incidence of CLI ranges between 500 and 1000 new cases out of one million people per year, with the highest rates among the elderly, smokers, and those with diabetes. CLI is considered to be a critical public health issue. Attempts at revascularization are often unsuccessful. [More]
Selenium supplementation may have positive and negative effects on immune system

Selenium supplementation may have positive and negative effects on immune system

A more thorough evaluation of selenium supplementation is needed, to better understand its benefits to our immune system, and the risks. [More]
Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Pre-existing nutritional deficits, immune dysfunction may increase hepatitis E risk during pregnancy

Researchers from the Johns Hopkins Bloomberg School of Public Health have found a link between pre-existing nutritional deficits and immune dysfunction and the risk of hepatitis E infection during pregnancy. [More]
Vagus nerve stimulation effective in inhibiting cortical spreading depression

Vagus nerve stimulation effective in inhibiting cortical spreading depression

According to a study led by scientists at Massachusetts General Hospital, Harvard Medical School published in the journal Pain, vagus nerve stimulation (VNS) was found to suppress cortical spreading depression (CSD). [More]
Salk Institute scientists find new target for glioblastoma multiforme treatment

Salk Institute scientists find new target for glioblastoma multiforme treatment

Glioblastoma multiforme is a particularly deadly cancer. A person diagnosed with this type of brain tumor typically survives 15 months, if given the best care. The late Senator Ted Kennedy succumbed to this disease in just over a year. [More]
New, personalized approach to detecting low back pain

New, personalized approach to detecting low back pain

Scientists at The Feinstein Institute for Medical Research have discovered a new, personalized approach to diagnosing low back pain. The findings from a clinical study show that serum levels of the proinflammatory cytokine interleukin-6 (IL-6) vary in individuals with lumbar intervertebral disc disease and that biochemical profiling of circulating cytokines may assist in refining personalized diagnoses of disc diseases. [More]
Does cancer affect memory? An interview with Associate Professor Janette Vardy

Does cancer affect memory? An interview with Associate Professor Janette Vardy

The study evaluated cognitive function in patients with colorectal cancer. It characterized the incidence and severity of cognitive impairment in people with colorectal cancer (CRC) compared to healthy controls. [More]
Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

My laboratory’s long standing interest is the study of the signaling capabilities of stem cells, both under homeostatic conditions [More]
New study describes STING protein's role in potential suppression of colorectal cancer

New study describes STING protein's role in potential suppression of colorectal cancer

A new study published today by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine reports on a key finding about the immune system's response to tumor development following studies on colorectal cancer. [More]
Findings show promising evidence for creating broad-spectrum antiviral

Findings show promising evidence for creating broad-spectrum antiviral

UW researchers working in collaboration with Kineta Inc. and the University of Texas at Galveston have shown that making a drug-like molecule to turn on innate immunity can induce genes to control infection in several -known viruses. [More]
Scientists reveal major players in severe muscle damage caused by sepsis

Scientists reveal major players in severe muscle damage caused by sepsis

Scientists from the Institut Pasteur, Paris Descartes University, Sainte-Anne Hospital and the CNRS have recently published a paper in Nature Communications in which they reveal major players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery. [More]
Human-gut-on-a-chip model offers hope for patients suffering from IBD

Human-gut-on-a-chip model offers hope for patients suffering from IBD

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst can lead to life-threatening complications. [More]
CytoSorbents partners with Hoang Long Pharma to bring CytoSorb to Vietnam

CytoSorbents partners with Hoang Long Pharma to bring CytoSorb to Vietnam

CytoSorbents Corporation, a leader in critical care immunotherapy commercializing its CytoSorb extracorporeal cytokine adsorber to control deadly inflammation using blood purification, today announced an exclusive multi-year distribution agreement with Hoang Long Pharma, a medical distributor in Vietnam specializing in the distribution of innovative pharmaceuticals, biologics, and devices to treat patients suffering from critical illnesses, immunologic disorders and deficiencies, and infections. [More]
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