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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Broad Institute purchases 30 additional Genome Analyzers from Illumina

6. November 2009 03:23
Illumina, Inc. today announced that the Broad Institute has purchased 30 additional Genome Analyzers, increasing its total installed base of Illumina systems to 89. [More]

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Scientists identify molecular disparity between iPS cells and embryonic stem cells

5. November 2009 03:21
The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult cells, according to new research from Johns Hopkins and Harvard. [More]

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Enzo Biochem to release a new catalog dealing with epigenetics and chromatin modification

15. October 2009 09:02
Enzo Biochem, Inc. today said that its Life Sciences subsidiary will release a new catalog dealing with “Epigenetics & Chromatin Modification” at the Society for Neuroscience’s, Neuroscience 2009 conference, beginning October 17, 2009, in Chicago, Illinois. [More]

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Orion Genomics enters collaboration and license agreement with Novartis Pharma

12. October 2009 08:40
Orion Genomics today announced that it has entered into a multi-year collaboration and license agreement with the molecular diagnostics unit of Novartis Pharma AG. Under the collaboration, the parties seek to discover novel epigenetic biomarkers, and both parties have rights to independently develop and commercialize diagnostic products in their respective fields. [More]

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NIH awards $1.9 million grant to Pacific Biosciences

8. October 2009 08:04
Pacific Biosciences, a private company developing a disruptive technology platform for real-time detection of biological events at single molecule resolution, today announced that it has received grants totaling more than $1.9 million from the National Institutes of Health (NIH) as part of the American Recovery & Reinvestment Act of 2009 Research and Research Infrastructure “Grand Opportunities” grants program. [More]

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Researchers identify tumor-suppressing genes to diagnose the phase of laryngeal cancer

8. October 2009 02:27
Researchers at Henry Ford Hospital have identified tumor-suppressing genes that may provide a more accurate diagnosis of disease stage and survival for laryngeal cancer patients than current standards. [More]

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Clinical Genomics extends collaboration with CSIRO

7. October 2009 02:58
Sydney-based Clinical Genomics Pty Ltd and CSIRO have entered into a new phase in their collaboration to develop improved diagnostics for cancers of the colon and rectum (bowel cancer). [More]

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Researchers show that DNA methylation plays a crucial role for cancer stem cells

7. October 2009 02:56
During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation. [More]

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JCA-Mauvernay Award presented to Dr Toshikazu Ushijima for his research in oncology

5. October 2009 04:17
Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, and the Japanese Cancer Association (JCA) presented 'The JCA-Mauvernay Award' to Dr Toshikazu Ushijima from the National Cancer Center Research Institute in Tokyo, for his outstanding and innovative research in basic science in the "epigenetic field for cancerization". [More]

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Study identifies new genes associated with head and neck cancer

5. October 2009 02:05
A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States. [More]

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Epigentek Group releases SuperSense Methylated DNA Quantification kit

1. October 2009 09:17
Epigentek Group Inc. today announced that it released the SuperSense(TM) Methylated DNA Quantification Kit to complete its line of methylated DNA quantification products. The SuperSense(TM) kit fluorometrically measures global DNA methylation shifts. [More]

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Rush University receives grants to study how epigenomic changes define cognitive decline

1. October 2009 05:34
The National Institutes of Health has awarded Rush University Medical Center approximately $5.5 million in grants to study how epigenetic changes - chemical modifications to genes that result from diet, aging, stress, or environmental exposures - define and contribute to memory formation and cognitive decline. Results from the studies could profoundly alter the way the medical community understands, diagnoses, and treats Alzheimer's disease, according to the researchers. [More]

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Austrian Institute of Technology adopts Arrayit's Microarray Platform for detecting dangerous pathogens

28. September 2009 07:48
Arrayit Corporation, a proprietary life sciences and technology leader, disclosed that its Microarray Platform has been adopted by Austrian Institute of Technology. [More]

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Study on how epigenetic changes contribute to congnitive decline

28. September 2009 07:18
The National Institutes of Health has awarded Rush University Medical Center approximately $5.5 million in grants to study how epigenetic changes - chemical modifications to genes that result from diet, aging, stress, or environmental exposures - define and contribute to memory formation and cognitive decline. Results from the studies could profoundly alter the way the medical community understands, diagnoses, and treats Alzheimer's disease, according to the researchers. [More]

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GI cancer detection simpler and cost-effective with new blood tests

21. September 2009 04:47
Berlin, Germany: Promising results from two new blood tests that can aid in the early identification of patients with gastrointestinal (GI) cancers will be presented at Europe's largest cancer congress, ECCO 15 - ESMO 34 [1], in Berlin today (Monday September 21). The tests will make GI cancer detection simpler, cost-effective, and more acceptable to patients than current methods, the researchers say. [More]

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