DNA Methylation News and Research

RSS

DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Study links air pollution to increased colorectal cancer risk through DNA changes

Researchers reveal how air pollution increases colorectal cancer (CRC) risk through epigenetic changes, using a large-scale study and Mendelian randomization to demonstrate ambient pollution’s impact on CRC mortality and incidence in China.

21 Apr 2024

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

A new study conducted by researchers at Tampere University and Tampere University Hospital revealed how aberrant epigenetic regulation contributes to the development of atypical teratoid/rhabdoid (AT/RT) tumors, which are aggressive brain tumors that mainly affect young children.

15 Apr 2024

Pregnancy speeds up biological aging in women, study suggests

Pregnancy may carry a cost, reports a new study from the Columbia University Mailman School of Public Health.

8 Apr 2024

Predicting treatment response in common blood cancer with DNA methylation profiling

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the patient will respond to treatment.

28 Mar 2024

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

Unraveling epigenetic contributions to autoimmune skin diseases

The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein.

25 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

E-cigarette users experience similar DNA changes to specific cheek cells as smokers

E-cigarette users with a limited smoking history experience similar DNA changes to specific cheek cells as smokers, finds a new study led by researchers at UCL (University College London) and University of Innsbruck.

20 Mar 2024

Non-invasive blood test shows 83% sensitivity in detecting colorectal cancer, offering hope for early diagnosis

The performance of a blood-based testing method that uses cell-free deoxyribonucleic acid (DNA) to screen for colorectal cancer.

18 Mar 2024

Understanding the genetic and cellular impact of smoking

It's no secret that smoking is extremely detrimental to health. Tobacco smoke contains thousands of chemicals, including carcinogens, increasing the risk of cancer, cardiovascular and respiratory diseases.

14 Mar 2024

New insights into the evolution of genomic imprinting

Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father.

6 Mar 2024

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses.

1 Mar 2024

Educational attainment linked to slower aging and increased longevity

Participants in the Framingham Heart Study who achieved higher levels of education tended to age more slowly and went on to live longer lives as compared to those who did not achieve upward educational mobility, according to a new study at Columbia University Mailman School of Public Health and The Robert N. Butler Columbia Aging Center.

1 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

Study reveals distinct molecular features of proximal and distal colon cancers

The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers.

27 Feb 2024

Link between gut microbiome and premature aging unveiled in chronic HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., has demonstrated, with his lab and collaborators, a connection between viral damage to the gut and premature biological aging.

22 Feb 2024

Mediterranean diet linked to better semen quality, study finds

A systematic review reveals that adherence to the Mediterranean diet improves semen quality in men of reproductive age, suggesting a positive impact on male reproductive health.

19 Feb 2024

New epigenetic clocks distinguish aging causes and effects

What causes us to age? New "clocks" developed by researchers may help point to the answers. Investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, unveil a new form of epigenetic clock – a machine learning model designed to predict biological age from DNA structure.

14 Feb 2024

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

14 Feb 2024

Study reveals the long-term effects of smoking on immunity

Like other factors such as age, sex and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scientists at the Institut Pasteur using the Milieu Intérieur cohort of 1,000 healthy volunteers, established to understand variability in immune responses.

14 Feb 2024

DNA Methylation News and Research

Further Reading

Study links air pollution to increased colorectal cancer risk through DNA changes

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

Pregnancy speeds up biological aging in women, study suggests

Predicting treatment response in common blood cancer with DNA methylation profiling

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Unraveling epigenetic contributions to autoimmune skin diseases

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

E-cigarette users experience similar DNA changes to specific cheek cells as smokers

Non-invasive blood test shows 83% sensitivity in detecting colorectal cancer, offering hope for early diagnosis

Understanding the genetic and cellular impact of smoking

New insights into the evolution of genomic imprinting

Exploring the epigenetic impact of smoking across racial and ethnic groups

Educational attainment linked to slower aging and increased longevity

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Study reveals distinct molecular features of proximal and distal colon cancers

Link between gut microbiome and premature aging unveiled in chronic HIV patients

Mediterranean diet linked to better semen quality, study finds

New epigenetic clocks distinguish aging causes and effects

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals the long-term effects of smoking on immunity

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest Life Science News