DNA Polymerase News and Research

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A DNA polymerase is an enzyme that catalyzes the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are most well-known for their role in DNA replication, in which the polymerase "reads" an intact DNA strand as a template and uses it to synthesize the new strand. The newly-polymerized molecule is complementary to the template strand and identical to the template's original partner strand. DNA polymerases use a magnesium ion for catalytic activity.

Breakthrough technique unveils secrets of "backtracking" in gene regulation

A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.

9 Feb 2024

Rare bacterial strain yields groundbreaking compounds to combat hepatitis B

Scientists have discovered new antiviral compounds from a rare bacterial strain, offering a novel approach to target hepatitis B virus. These compounds work by altering membrane permeability in infected cells, leading to the release of immature viral particles, a mechanism distinct from current HBV treatments.

28 Nov 2023

Researchers identify key factors involved in DNA repair mechanism

Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies.

12 Nov 2023

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

An online resource for studying the relationship between mutational signatures and topographical characteristics across human cancer.

28 Aug 2023

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing.

25 Aug 2023

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Research investigates the potential health benefits of grape consumption by examining its impact on the human microbiome. By analyzing microbiome composition and metabolites, the study provides insights into the relationship between grapes and human health.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

Researchers pioneer a new method for fast miRNA amplification and detection

In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes.

24 Apr 2023

Mediterranean diet and the modulation of mitochondrial function

Researchers reviewed the current knowledge related to the Mediterranean diet (MedDiet) and the role of mitochondria concerning health outcomes.

7 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Researchers from Nigeria and the United Kingdom (U.K.) analyzed mpox virus genomes and found that divergent lineages of the mpox virus exhibiting human-to-human transmission existed in the Nigerian population before the 2022 spread of the virus outside of the endemic regions.

10 Jan 2023

New research on DNA-repair enzyme could help enhance cancer drug development

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could help make a particular enzyme a promising target for precision cancer therapy.

6 Jan 2023

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Researchers provided an overview of existing molecular methods for mpox virus detection.

13 Dec 2022

Specific mutations in the monkeypox virus contribute to its continued infectiousness

Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and -; similar to COVID-19 -; mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more people.

4 Nov 2022

DNA Polymerase News and Research

Further Reading

Breakthrough technique unveils secrets of "backtracking" in gene regulation

Rare bacterial strain yields groundbreaking compounds to combat hepatitis B

Researchers identify key factors involved in DNA repair mechanism

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Molecular mechanism behind a DNA repair pathway revealed

Researchers pioneer a new method for fast miRNA amplification and detection

Mediterranean diet and the modulation of mitochondrial function

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

New research on DNA-repair enzyme could help enhance cancer drug development

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Specific mutations in the monkeypox virus contribute to its continued infectiousness

How smallpox and monkeypox viruses affect the nervous system

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

Würzburg scientists are working on the development of new drugs to combat monkeypox

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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