Deep Brain Stimulation News and Research

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Deep brain stimulation (DBS) is a surgical procedure used to treat a variety of disabling neurological symptoms—most commonly the debilitating symptoms of Parkinson’s disease (PD), such as tremor, rigidity, stiffness, slowed movement, and walking problems. The procedure is also used to treat essential tremor, a common neurological movement disorder. At present, the procedure is used only for patients whose symptoms cannot be adequately controlled with medications.

New method provides valuable insights into the brain's noradrenaline system

An international team of researchers has provided valuable insights into the brain's noradrenaline (NA) system, which has been a longtime target for medications to treat attention-deficit/hyperactivity disorder, depression, and anxiety.

24 Oct 2023

Researchers receive $3.6 million to test novel diagnosis and treatment combination for diabetic neuropathy

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24 Oct 2023

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

A recent study from the lab of Dr. Jianrong Tang, associate professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital shows that deep brain stimulation (DBS) of a specific brain region results in a significant and sustained improvement of memory in Rett mice.

13 Oct 2023

Can deep brain stimulation unlock the cure for severe depression?

A multidisciplinary team of clinicians, engineers, and neuroscientists has identified a unique biomarker in the brain that indicates recovery from treatment-resistant depression, utilizing deep brain stimulation (DBS) and artificial intelligence. The discovery, which allows for real-time monitoring and tailoring of treatment, could revolutionize the approach to managing severe forms of depression.

21 Sep 2023

New brain biomarker predicts recovery from treatment-resistant depression

Using a novel deep brain stimulation (DBS) device capable of recording brain signals, researchers have identified a pattern of brain activity or "biomarker" related to clinical signs of recovery from treatment-resistant depression.

20 Sep 2023

Brain circuitry repair offers hope for new Parkinson's disease treatments

Van Andel Institute scientists have identified a series of processes that help the brain adapt to damage caused by breakdowns in circuits that govern movement, cognition and sensory perception.

24 Aug 2023

Phase I trial shows promise: Brain stimulation spurs upper-extremity recovery in stroke patients

Researchers performed an open-label phase I trial.

18 Aug 2023

Deep brain stimulation shows promise for post-stroke rehabilitation

A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients by Cleveland Clinic researchers has shown that using DBS to target the dentate nucleus – which regulates fine-control of voluntary movements, cognition, language, and sensory functions in the brain – is safe and feasible.

14 Aug 2023

Similarities in gene expression between post-mortem and living human brains

Researchers compare human prefrontal cortex gene expression between living and post-mortem samples.

7 Aug 2023

Lesion network mapping identifies new brain circuit linked to epilepsy

Focal epilepsy affects over 30 million patients worldwide and is commonly caused by brain lesions, such as stroke.

3 Jul 2023

New study may help improve diagnosis of cognitive disability in Parkinson's disease

A few minutes of data recorded from a single electrode placed on top of the head may be sufficient to predict thinking problems, including dementia, in patients with Parkinson's disease (PD).

12 Jun 2023

Researchers identify brain signatures for chronic pain in a small group of individuals

For the first time, researchers have recorded pain-related data from inside the brain of individuals with chronic pain disorders caused by stroke or amputation (phantom limb pain).

22 May 2023

Pioneering focused ultrasound trial shows promising results for patients with Parkinson’s disease

The findings of a major international trial to test a high-tech, scalpel-free approach to treating movement problems caused by Parkinson’s disease have been published in the prestigious New England Journal of Medicine.

13 May 2023

Activation of adult-born neurons restores cognitive, affective function in Alzheimer’s mouse models

People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression.

6 Apr 2023

Mapping neural connections in OCD patients can predict improvements after deep brain stimulation

Deep brain stimulation (DBS) is a promising therapy for treatment-resistant obsessive-compulsive disorder (OCD).

29 Mar 2023

Spectroscopy probe could make deep brain stimulation safer and improve success rates

Deep brain stimulation (DBS) has become an increasingly common treatment for patients with advanced Parkinson's disease, but the procedure still carries significant risks.

23 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

Minimally invasive focused ultrasound treatment improves symptoms in patients with Parkinson's disease

Patients with Parkinson's disease achieved a significant improvement in their tremors, mobility, and other physical symptoms after having a minimally invasive procedure involving focused ultrasound, according to a new study today published in the New England Journal of Medicine.

23 Feb 2023

Study finds distinct differences in how the brain releases dopamine in patients with alcohol use disorder

Dopamine is a neurotransmitter that's made in the brain and acts as a chemical messenger, communicating between nerve cells in the brain and the rest of the body.

7 Feb 2023

Data-driven algorithm predicts deep brain stimulation parameters for Parkinson’s treatment

Researchers assesses the effects of stimulation parameters suggested by a recently published data-driven algorithm (StimFit) based on neuroimaging data.

31 Jan 2023