Degenerative Disease News and Research

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Nanopore sequencing unveils novel telomere length patterns

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Research provides first evidence for a possible cause of familial ALS

Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement begin to die and muscle control is progressively lost, leading to a fatal outcome.

22 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

UniSA researchers seek solutions for chronic pain in Parkinson's disease

Parkinson’s disease is the second most common neurological disease in Australia.

7 Feb 2024

AI shows the same accuracy as a cardiologist in detecting rheumatic heart disease

Artificial intelligence (AI) has the potential to detect rheumatic heart disease (RHD) with the same accuracy as a cardiologist, according to new research demonstrating how sophisticated deep learning technology can be applied to this disease of inequity.

16 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

Unveiling the role of EBV in the onset and progression of multiple sclerosis

Recent evidence strongly implicates infection by the Epstein-Barr virus (EBV) as the trigger for development of multiple sclerosis (MS). An international research team is now gathering to unveil the role of EBV in the onset and progression of the MS disease.

20 Sep 2023

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

17 Jul 2023

Alarming rise: New cases of dementia surging in elderly population of Wales, UK

Dementia cases are increasing among the elderly population, with a rise in new diagnoses and a growing number of people living with the disease. This trend poses challenges for healthcare systems as the aging population with dementia continues to grow.

20 Jun 2023

Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

Study examines whether alcohol-associated burn injuries impair cognitive function

The relationship between alcohol use and burn injuries is a negative one in multiple ways. Not only are about 50% of adults who sustain burn injuries intoxicated at the time of injury, suggesting that alcohol use may have contributed to the incident, but alcohol use among burn-injured patients is associated with more severe complications, delayed recovery, and increased morbidity and mortality.

10 Apr 2023

Playing tackle football at an early age increases risk for brain decline later

The degenerative brain disease known as CTE, or chronic traumatic encephalopathy, has become a specter haunting football.

20 Mar 2023

Researchers fabricate first wearable sensor to detect and monitor muscle atrophy

Researchers at The Ohio State University have fabricated the first wearable sensor designed to detect and monitor muscle atrophy.

17 Mar 2023

How does dietary intervention affect aging?

Aging is a process that includes multiple interwoven mechanisms that interact with lifestyle factors. A new review seeks to encapsulate the available information on the effect of diet on aging at the cellular level in humans.

14 Mar 2023

UB researchers develop new tool to assess the presence and severity of sarcopenia

Sarcopenia is a degenerative disease characterized by a pathological decrease in muscle strength that particularly affects older people.

13 Mar 2023

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Genetic discovery may pave the way to new diagnostic approaches, treatments for motor neurone diseases

A new genetic discovery adds weight to a theory that motor neurone degenerative diseases are caused by abnormal lipid (fat) processing pathways inside brain cells.

20 Jun 2022

Dietary supplements can slow progression of age-related macular degeneration, NIH study confirms

The Age-Related Eye Disease Studies (AREDS and AREDS2) established that dietary supplements can slow progression of age-related macular degeneration (AMD), the most common cause of blindness in older Americans. In a new report, scientists analyzed 10 years of AREDS2 data.

2 Jun 2022

Topical ocular administration of progesterone could be viable treatment for retinitis pigmentosa

Retinitis pigmentosa is a degenerative disease affecting the photoreceptor cells in the retina, known as cones and rods.

30 May 2022